The shunted loudspeaker with a negative impedance converter is a physical system with multiple influencing parameters. In this paper, a fully exhaustive backtracking algorithm was used to optimize these parameters, such as moving mass, total stiffness, damping, coil inductance, force factor, circuit resistance, inductance and capacitance, in order to obtain the best sound absorption in a specific frequency range. Taking the maximum average sound absorption coefficient in the range of 100–450 Hz as the objective function, the optimized parameters of the shunted loudspeaker were analyzed. Simulation results indicated that the force factor and moving mass can be sufficiently reduced in comparison with that of a typical four-inch loudspeaker available on the market. For a given loudspeaker from the market as an example, the four optimized parameters of the shunted loudspeaker were given, and the sound absorption coefficient was measured for verification. The measured results were in good agreement with the predicted results, demonstrating the applicability of the algorithm.