An anatase-based nanostructured TiO2 thin film paint was sprayed on FTO conducting glass to create dye-sensitized solar cells. Turmeric (Curcuma longa) and CaCO3 were used as natural sensitizers (DSSCs). FTIR and UV-Vis spectrophotometry was used to analyze the functional groups and optical characteristics of the dyes at absorbing photon energy of the semiconductor thin films, respectively. Both the XRD and UV results show that TiO2 has an anatase phase structure that is consistent with its broadband gap nature. The PL spectra of natural dyes were examined to determine their optical properties and the intensity of PL emission reported a bandgap of 4.72 eV and 4.95 eV respectively. The efficiency of the DSSC using Kumkum dye in ethanol is 0.9%, whereas in DI is 0.2%. Curcumin is a flavonoid polyphenol which is a very effective light-harvesting derivative required for the creation of charge carriers and generation of electric current has been found to be present in turmeric extract and is subjected to the coloring of natural sensitizers which enhance the absorption coefficient. Data Availability StatementThe datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.