The fractional powers of generators for analytic operator semigroups are used for the proof of the existence and uniqueness of a solution of the Cauchy problem to a first order semilinear equation in a Banach space. Here, we use an analogous construction of fractional powers Aγ for an operator A such that −A generates analytic resolving families of operators for a fractional order equation. Under the condition of local Lipschitz continuity with respect to the graph norm of Aγ for some γ∈(0,1) of a nonlinear operator, we prove the local unique solvability of the Cauchy problem to a fractional order quasilinear equation in a Banach space with several Gerasimov–Caputo fractional derivatives in the nonlinear part. An analogous nonlocal Lipschitz condition is used to obtain a theorem of the nonlocal unique solvability of the Cauchy problem. Abstract results are applied to study an initial-boundary value problem for a time-fractional order nonlinear diffusion equation.