Sissoo (Dalbergia sissoo) is a deciduous tree, native to Nepal and the Indian subcontinent. The tree is traditionally used for making furniture, fodder and herbal medicine. It is also used as shelter-wood, and in conserving soil in degraded areas. This review focuses on the health management practices against pathogenic constraints in sissoo. Literature published till June 2020 was considered to understand the biology of the tree species and associated pathogens apart from understanding the management practices to treat the diseases. Despite the massive significance of this tree, available publications on the pathogenic risks and the strategies to cope with them are unnoticed so far. This article expects to bring together information on sissoo tree’s biology, pathogen attacks and its management. Of various fungal diseases in sissoo, this article deals with only two of the fungal diseases, Fusarium solani and Ganoderma lucidum, which cause dieback and root rot in sissoo, respectively. The findings highlighted can further reinforce the current sissoo management and pathogen control strategies and improve its health to augment high quality timber.