The aerospace and defense industries could benefit from magnesium matrix composites because of their favorable mechanical and physical characteristics, in addition to their low density. Magnesium-based alloys and composites are also recognized for their biodegradability and biocompatibility, making them suitable for orthopedic implants. The addition of reinforcing elements significantly improves high specific strength to stiffness, wear resistance, damping, resistance to deformation under constant load, and resilience to repeated stress. Additionally, machinability is equally important during fitment in any such application. In this study, drilling experiments were conducted on Mg/B4C composites with two different volume reinforcement percentages (5% and 10%), and the results were compared under various cutting conditions. During the drilling process under different cutting conditions, the thrust force and torque were analyzed using a dynamometer and the surface roughness of the hole surface and chip formation were also analyzed for different conditions.