In order to correctly understand the rock multi-fissure interactions and crack propagation laws, three-point bending fracture tests of the marble semi-circular bend samples (SCB samples) are carried out, and the crack propagation processes are simulated by the Smoothed Particle Hydrodynamics (SPH) method. Results show that: Cracks initiate from the guide fissure tip and propagate vertically in the SCB sample with no obstacle fissures; The overlap positions of crack1 and the obstacle fissure are biased towards the lower left end of the obstacle fissure with the increase of the inclination angle α; With the increase of the eccentric distance d, the overlap positions of crack1 and the obstacle fissure are biased towards the upper right end of the obstacle fissure; The peak load of the samples decreases with the increase of inclination angle α, while increases with the increase of eccentric distance d. The “failure coefficient” η is introduced into the conventional SPH momentum equations, which can simulate the multi-fissure propagations of the SCB samples. The simulation results are consistent with the experimental results, and the mechanisms of the crack propagation morphologies between the guide fissure and the obstacle fissure are discussed. The research results can provide some references for correctly understanding the crack propagation mechanisms of multi-fissure rock masses and the applications of the SPH method into simulating rock multi-fissure interactions.