A variety of topological structures, including hollow warren structure (cross warren, diamond warren, triangular warren, four layer warren), 2D lattice structure (hexagonal honeycomb, tetragonal honeycomb), closed-cell foam structure (hexagonal foam, tetragonal foam), open-cell foam structure (multi-layer egg box), and three-dimensional lattice structure (pyramid, tetrahedron, X), were fabricated using the Superplastic Forming/Diffusion Bonding (SPF/DB) process. Finite element simulation was employed to investigate the forming process and mechanical behavior of different topological structures. Extensive analysis was carried out on deformation behavior and corresponding gas loading curves. In addition, the efficiency and the load-bearing features of different topological structures were also investigated. The future development of multifunctional topological structure was prospected.