Real concrete structures can suffer simultaneously from the alkali-silica reaction (ASR) and delayed ettringite formation (DEF), resulting in expansion of the concrete and surface map cracking. This damage can lead to serious durability problems. The respective effects of ASR and DEF have been studied, but the cracking behavior of concrete when they act together remains unclear. In this study, a three-dimensional rigid body spring model (3D RBSM) is used to simulate the cracking and mechanical property degradation of concrete under coupled ASR and DEF. A parametric study is conducted to understand various combinations of ASR and DEF. In line with previous studies by the authors on independent ASR/DEF damage, expansions caused by ASR and DEF are, respectively, introduced as strains at the mortar-aggregate interface and in mortar elements. Due to a confinement effect, specimens subjected to coupled expansion may suffer less expansion or cracking than when only one of the degradations is acting. The model clearly visualizes the cracking process and stress development as the degree of coupled expansion increases. More importantly, based on the simulated results, the interactions of the two types of expansion are revealed by correlating the degradation in mechanical properties with internal cracking behavior. Further, the confinement effect arising on application of the second type of expansion is quantitatively examined. While there is no significant change in stiffness, compressive strength in some cases increases with expansion as larger cracks close up under the confinement effect. This kind of investigation of coupled effects is difficult to quantitatively analyze through experimentation, but this work demonstrates that it is possible using RBSM simulations.