Thiocyanate Compounds Research Articles

Octahedral nickel(II) complexes with the tripod ligand tris(2-dimethylarsionethyl)amine

Nickel(II) complexes with the tripod tetradentate ligand tris(2-dimethylarsinoethyl)amine (Me 6nas 3) having the general formula [NiX 2(Me 6nas 3)], X = Cl, Br, I, NCS, were prepared and characterized. All the complexes have octahedral geometry: the chloride and bromide derivatives are monomeric; the iodide and thiocyanate compounds have a polymeric chain structure in which the ligand Me 6nas 3 is bridging between two nickel atoms.

Use of x-ray k-absorption spectroscopy for the determination of bonding in thiocyanate compounds

X-ray K-absorption edges of sulfur in metal complexes with a thiocyanate group have been investigated in order to find out the mode of coordination of the thiocyanate group in metal complexes. The shapes of the absorption edges revealed that the formation of M-S bonds leads to a characteristic absorption maximum on the low energy side of the edge. The intensity of this band is markedly lowered in thiocyanate complexes containing a mixture of linkage isomers.

The azo coupling of active methylene thiocyanate compounds. A convenient synthesis of 5-imino-4-aryl-2-benzoyl-Δ 2-1,3,4-thiadiazolines

The azo coupling of active methylene thiocyanate compounds. A convenient synthesis of 5-imino-4-aryl-2-benzoyl-Δ 2-1,3,4-thiadiazolines

Complexes of organometallic compounds : XXXI. Studies on organolead(IV) thiocyanate compounds

The configurations of (CH 3) 3PbNCS, (C 6H 5) 3PbNCS, (C 6H 5) 2Pb(NCS) 2, (C 6H 5) 3Pb(NCS) 2 − and (C 6H 5) 2Pb(NCS) 4 2− have been investigated in the solid and (except for the insoluble diphenyl derivative) in solution. From infrared spectroscopy it is deduced that the compounds are isothiocyanates in both states, and there is evidence for a polymeric nature of the solid neutral species involving bridging through NCS. PMR and osmometric investigations show that five-coordinate species (CH 3) 3Pb(NCS)·(CH 3) 2CO are present in acetone solution. Possible configurations are discussed.

Studies on chemotherapeutics. VI. On the antimicrobial activity and syntheses of halogen-substituted-arylthiocyanate compounds

1) Acetylation of the thiocyanate compounds (I and II) with acetic anhydride in pyridine afforded the monoacetyl (III) and diacetyl (IV) compounds. 2) Halogenated arylthiocyanate compounds (V to XXVIII) were prepared by dissolving 3-chloro-4-thiocyanatoaniline, 1-amino-4-thiocyanatonaphthalene, 8-amino-6-chloroquinoline, or 8-amino-6-chloro-5-thiocyanatoquinoline in xylene, added with haloacetyl chloride, and heated under reflux for 1 hour. 3) An acid amide compound (XXIX) was prepared by the application of hydrogen peroxide to 5-cyano-1, 6-naphthyridine in acetone. 4) The compounds so synthesized (III to XXIX) were tested for their antibacterial activity in vitvo.

2-Chloro-4-amino-5-(p-halogenophenoxy)phenylthiocyanate類の合成およびその抗菌性について(第1報)

1) Application of 2, 4-dichloronitrobenzene to the potassium salts 2, 5-dichloro-, 2, 4, 5-trichloro-, p-fluoro-, and p-iodophenols, and p-chlorothiophenol, in the presence of copper powder, afforded (2-phenoxy-5-chloro)nitrobenzenes (III to VI) and [2-(4-chloro-phenylthio)-5-chloro] nitrobenzene (VII). These nitre compounds were reduced to the amino compounds (XI to XVIII) with stannous chloride and hydrochloric acid. Thiocyanation of these compounds, 2-amino-4-chlorophenol, and XIX, by treatment with ammonium thiocyanate and bromine in acetic acid afforded the thiocyano compounds (XXI to XXX). 2) Reaction of the potassium salts of p-chloro- and p-bromophenols with 2-chloro-, 4-bromo-, 2-chloro-4-fluoro-, and 2-chloro-4-iodo-nitrobenzenes, in the presence of copper powder, afforded the nitro compounds (XXXI to XXXVI), which were reduced with stannous chloride and hydrochloric acid to the amino compounds (XXXVII to XLII), and further derived to the thiocyano compounds (XLIII to XLVII) by treatment with ammonium thiocyanate and bromine. 3) All these thiocyanate compounds were submitted to antifungal tests against Candida and Trichophyton. None of the compounds showed much activity against Candida but some of the compounds had activity against Trichophyton comparable to or better than that of I.

Chemistry of the cyclopentadienyl metal carbonyls: IV. New Perfluoroalkyl derivatives of cobalt

New compounds of the formula C 5H 5Co(CO)C 3F 7X (X = Br, Cl) can be prepared from sodium bromide or chloride and C 5H 5Co(CO)C 3F 7OClO 3, the latter reagent being prepared in situ from C 5H 5Co(CO)C 3F 7I and AgClO 4 in benzene. A similar reaction with sodium cyanide or sodium thiocyanate did not give the monomeric cyanide or thiocyanate compounds: from the thiocyanate reaction a trimer [C 5H 5CoC 3F 7SCN] 3 was formed, and from the cyanide ion reaction the product obtained was a polymeric species [C 5H 5CoC 3F 7CN] x ( x~4.5). The structures of these two species involve bridging CN and SCN groups. A dimeric halogen bridge species [C 5H 5CoC 3F 7I] 2 is also described; this material is interconvertible with C 5H 5Co(CO)C 3F 7I by the equilibrium: 2 C 5H 5Co(CO)C 3F 7I ⇄ 2 CO + (C 5H 5CoC 3F 7I) 2 Several ionic compounds containing perfluoropropyl groups are formed in reactions of C 5H 5Co(CO)C 3F 7I or [C 5H 5CoC 3F 7I] 2 and (C 4H 9) 4N +I −, KCN, or NH 4 +F −. These compounds contain anions of the general formula C 5H 5CoC 3F 7(X,Y) − [X,Y = I 2, (CN) 2, IF] and arise from displacement of a carbonyl or iodine bridge by the halide or cyanide anion.

多硫化アルカリとの反応による硫シアン化合物の定量及び微量検出 (第2報)

The determination method for benzyl thiocyanate using alkali polysulfide, described in the previous paper, was extended to other thiocyanate compounds and found that the method can be applied generally. A microdetection method for thiocyanate group was also proposed (in which a drop of Na2S3 or Na2S4 is added to one drop of the alcoholic solution of the sample, warmed for 1 minute in a water bath, and 1 drop of 10% H2SO4 is added. After warming the mixture for some time, 1 drop of 1% HCl solution of FeCl3 is added after the mixture has cooled and a red coloration appears in the presence of a thiocyanate compound. Limit of detection is 1 γ, and the limit of concentration is 1:10, 000 to 1:15, 000). The corresponding disulfides were isolated in 80-90% yield from the reaction of phenyl-, 2-carboxyphenyl-, 2, 4-dinitrophenyl-, and 4-methoxynaphthyl thiocyanate and thiocyanoacetanilide with sodium trisulfide. All the disulfides were isolated and identified. For the reaction of a thiocyanate compound and alkali polysulfide, a general formula (1) was forwarded and radical reactions (2-4) were assumed for it.

What is the mode of action of thiocyanate compounds in essential hypertension?

Excerpt INTRODUCTION Although the thiocyanate compounds have been used as remedies for essential hypertension since early in the Twentieth Century, our incomplete knowledge of their mode of action,...

Thiocyanate Compounds in the Urine of Schizophrenics

By thiocyanate compounds is meant a group of salts of thiocyanic acid (HCNS). Together with compounds of glycuronic and sulphuric acids, these salts are products of several detoxication processes. In the urine they are the end-products of the detoxication of substances formed during the breakdown of protein.