Thin Body Research Articles

Well-Being and Performance of Nursery Pigs Subjected to Different Commercial Vaccines Against Porcine Circovirus Type 2, Mycoplasma hyopneumoniae and Lawsonia intracellularis

Background/Objectives: Vaccination is a strategy in pig farming for the control of several pathogens, but commercial vaccines may have detrimental side effects. This study aimed to evaluate the effects of commercial vaccines on the control of porcine circovirus type 2 (PCV2), Mycoplasma hyopneumoniae (Mhp), and Lawsonia intracellularis (L. intracellularis) and their potential side effects on welfare, behavior, acute inflammation biomarkers (C-reactive protein and haptoglobin), and the performance of piglets during the nursery phase. Methods: A total of 240 piglets, both female and castrated males, with an average weight of 6.3 ± 0.9 kg were subjected to four treatments: T1-FLEXcombo® (Ingelvac®CircoFLEX and Ingelvac®MycoFLEX) + Enterisol® Ileitis; T2-FLEXCombo® + Porcilis® Ileitis; T3-Porcilis® PCV M HYO + Porcilis® Ileitis; and T4-FLEXCombo® + 0.9% saline solution. This study measured therapeutic interventions, body condition score, behavioral changes, rectal temperature, and inflammation biomarkers post-vaccination. Results: The T3 group required more therapeutic interventions and exhibited a 23.1% higher incidence of thin body condition (p < 0.05) and 10 times more animals with depressed behavior than T1 (p < 0.05). The piglets vaccinated for L. intracellularis (T2 and T3) had rectal temperatures exceeding 39.7 °C post-vaccination, significantly higher than in T1 (p < 0.05). The T1 animals showed five times more positive behavior traits 24 h after vaccination (p < 0.05). Touch response was 29% lower in the T2 and T3 groups, and the lying down behavior was higher in these groups compared to T1. Additionally, 41.7% of the T3 animals exhibited a sitting posture 48 h after vaccination. Higher serum C-reactive protein and haptoglobin levels were observed in T3 (p < 0.05) at 24 and 48 h post-vaccination. Feed intake was higher in T1 compared to T3 between 29 and 35 days of age. It is important to note that this study did not measure immune responses to the pathogens and did not include challenge tests, and therefore, it does not assess which vaccine is superior in pathogen control. Conclusions: The vaccine programs resulted in similar zootechnical performance. However, T1, T2, and T4 showed better effects on piglet welfare and behavior compared to T3.

Numerical Simulation on the Impact of Back Gate Voltage in Thin Body and Thin Buried Oxide of Silicon on Insulator (SOI) MOSFETs

Silicon-on-Insulator (SOI) technology provides a solution for controlling Short-Channel Effects (SCEs) and enhancing the performance of Metal-Oxide-Semiconductor Field-Effect Transistors (MOSFETs). However, scaling down SOI MOSFETs to a nanometer scale does not necessarily yield further scaling benefits. Introducing multiple gates, such as a double gate configuration, can effectively mitigate SCEs. Nonetheless, fabricating a flawless double gate structure is an exceedingly challenging endeavor that remains unrealized. The adoption of a back gate bias, with an asymmetrical thickness arrangement between the front and back gates, mimicking the behavior of a double gate, offers an alternative approach. This approach has the potential to modify the electrical characteristics of the device, thus potentially leading to improved control over SCEs. In this study, we employed 2D simulations using Atlas to investigate the influence of back gate biases, namely, -2.0 V, 0 V, and 2.0 V on a 10 nm silicon thickness at the top and a 20 nm buried oxide thickness for n-channel MOSFETs. We focused on key parameters, including threshold voltage (VTh), Drain Induced Barrier Lowering (DIBL), and Subthreshold Swing (SS). The results demonstrate that a negative back gate bias is the most favorable configuration, as it yields superior performance. This translates into more effectively controlled SCEs across all the parameters of interest.

Motion and self-motion of thin bodies in rarefied gas

One of the important tasks of space flight safety is the ability of a wing to maintain stability in an oncoming turbulent flow. In this case, the spacecraft must move the greatest distance. The paper studies the motion of a thin plate near a boundary in an oncoming flow of rarefied gas. At low Reynolds numbers, the effect of the boundary on the plate is studied, and the possibility of self-propulsion is shown.

Application of seismic inversion constrained geological modeling technology in quantitative characterization of thin reservoirs

Abstract With the gradual deepening of petroleum exploration and development, the scale of reservoir research in oil and gas reservoirs is getting smaller and smaller, and the demand for accuracy is getting higher and higher. During the development of clastic reservoirs in the Tarim Basin, the lithology of reservoir sand bodies changes rapidly and the lateral continuity is poor, so it is difficult to effectively identify the space distribution of sand bodies by relying solely on geological logging data. In this study, combined with the advantages of logging curve for vertical identification of sand bodies and seismic data for horizontal distribution identification of reservoirs, the seismic inversion constrained geological modeling technology is proposed to realize the quantitative characterization of thin reservoir sand bodies in developed oil and gas reservoirs :①Through the analysis of sensitive characteristic curve and the extraction of targeted seismic plane attributes, the feasibility evaluation of inversion in the target area is completed, and the seismic inversion results of thin reservoirs are generated. ②Based on the results of seismic inversion simulation, a high-precision 3D lithofacies geological model is constructed by analyzing the applicability of stochastic modeling method. ③ Combined with geological cognition, the physical property characterization of 3D lithofacies geological model is realized by physical property truncated simulation method, and the spatial distribution pattern of effective sand bodies is depicted. Through the application of this method in the study area A, the problem of certain deviation between reservoir inversion driven by conventional frame model and geological cognition is solved. While the spatial recognition ability of sand bodies is further improved, the quantitative characterization of thin reservoir physical properties is realized, which provides effective technical support for the subsequent development of oil and gas reservoirs.

(Invited) Mobility Enhancement Technology of Extremely-Thin Body Ge-on-Insulator Channel Mosfets

An extremely thin body (ETB) channel is mandatory for scaled nano-sheet structures to realize continuous miniaturization of CMOS devices. Here, mobility booster technologies to maintain high channel mobility are strongly needed, because surface roughness scattering significantly reduces mobility in such ETB channels. From this viewpoint, Ge-On-Insulator (GOI) or SiGe-On-Insulator (SGOI) channels are promising because of the low electron and hole effective mass along channel directions. It is theoretically shown that (111) GOI n-MOSFETs can hold high electron mobility even in the body thickness down to 2 nm. Thus, (111) GOI structures and n-MOSFETs are fabricated, and the electrical characteristics are studied. For p-MOSFETs, on the other hand, (110) surface orientation and application of compressive strain are still effective in boosting hole mobility in ETB channels. Here, (110) asymmetric compressive strain SGOI p-MOSFETs are experimentally demonstrated, and the body thickness dependencies of the effective mobility are examined.

Identification and Characterization of Novel Serpentoviruses in Viperid and Elapid Snakes.

Viruses in the subfamily Serpentovirinae (order Nidovirales, family Tobaniviridae) can cause significant morbidity and mortality in captive snakes, but documented infections have been limited to snakes of the Boidae, Colubridae, Homalopsidae, and Pythonidae families. Infections can either be subclinical or associated with oral and/or respiratory disease. Beginning in June 2019, a population of over 150 confiscated snakes was screened for serpentovirus as part of a quarantine disease investigation. Antemortem oropharyngeal swabs or lung tissue collected postmortem were screened for serpentovirus by PCR, and 92/165 (56.0%) of snakes tested were positive for serpentovirus. Serpentoviruses were detected in fourteen species of Viperidae native to Asia, Africa, and South America and a single species of Elapidae native to Australia. When present, clinical signs included thin body condition, abnormal behavior or breathing, stomatitis, and/or mortality. Postmortem findings included variably severe inflammation, necrosis, and/or epithelial proliferation throughout the respiratory and upper gastrointestinal tracts. Genetic characterization of the detected serpentoviruses identified four unique viral clades phylogenetically distinct from recognized serpentovirus genera. Pairwise uncorrected distance analysis supported the phylogenetic analysis and indicated that the viper serpentoviruses likely represent the first members of a novel genus in the subfamily Serpentovirinae. The reported findings represent the first documentation of serpentoviruses in venomous snakes (Viperidae and Elapidae), greatly expanding the susceptible host range for these viruses and highlighting the importance of serpentovirus screening in all captive snake populations.

FHOD-1 and profilin protect sarcomeres against contraction-induced deformation in C. elegans.

Formin HOmology Domain 2-containing (FHOD) proteins are a subfamily of actin-organizing formins important for striated muscle development in many animals. We showed previously that absence of the sole FHOD protein, FHOD-1, from Caenorhabditis elegans results in thin body wall muscles with misshapen dense bodies that serve as sarcomere Z-lines. We demonstrate here that mutations predicted to specifically disrupt actin polymerization by FHOD-1 similarly disrupt muscle development, and that FHOD-1 cooperates with profilin PFN-3 for dense body morphogenesis, and with profilins PFN-2 and PFN-3 to promote body wall muscle growth. We further demonstrate that dense bodies in worms lacking FHOD-1 or PFN-2/PFN-3 are less stable than in wild type animals, having a higher proportion of dynamic protein, and becoming distorted by prolonged muscle contraction. We also observe accumulation of actin and actin depolymerization factor/cofilin homolog UNC-60B in body wall muscle of these mutants. Such accumulations may indicate targeted disassembly of thin filaments dislodged from unstable dense bodies, possibly accounting for the abnormally slow growth and reduced body wall muscle strength in fhod-1 mutants. Overall, these results implicate FHOD protein-mediated actin assembly in forming stable sarcomere Z-lines, and identify profilin as a new contributor to FHOD activity in striated muscle development.

Parametric Analysis of Indium Gallium Arsenide Wafer-based Thin Body (5 nm) Double-gate MOSFETs for Hybrid RF Applications.

The electrical behavior of a high-performance Indium Gallium Arsenide (In- GaAs) wafer-based n-type Double-Gate (DG) MOSFET with a gate length (LG1= LG2) of 2 nm was analyzed. The relationship of channel length, gate length, top and bottom gate oxide layer thickness, a gate oxide material, and the rectangular wafer with upgraded structural characteristics and the parameters, such as switch current ratio (ION/IOFF) and transconductance (Gm) was analyzed for hybrid RF applications. This work was carried out at 300 K utilizing a Non-Equilibrium Green Function (NEGF) mechanism for the proposed DG MOSFET architecture with La2O3 (EOT=1 nm) as gate dielectric oxide and source-drain device length (LSD) of 45 nm. It resulted in a maximum drain current (IDmax) of 4.52 mA, where the drain-source voltage (VDS) varied between 0 V and 0.5 V at the fixed gate to source voltage (VGS) = 0.5 V. The ON current(ION), leakage current (IOFF), and (ION/IOFF) switching current ratios of 1.56 mA, 8.49Í10-6 μA, and 18.3Í107 μA were obtained when the gate to source voltage (VGS) varied between 0 and 0.5 V at fixed drain-source voltage (VDS)=0.5V. The simulated result showed the values of maximum current density (Jmax), one and twodimensional electron density (N1D and N2D), electron mobility (μn), transconductance (Gm), and Subthreshold Slope (SS) are 52.4 μA/m2, 3.6Í107 cm-1, 11.36Í1012 cm-2, 1417 cm2V-1S-1, 3140 μS/μm, and 178 mV/dec, respectively. The Fermi-Dirac statistics were employed to limit the charge distribution of holes and electrons at a semiconductor-insulator interface. The flat-band voltage (VFB) of - 0.45 V for the fixed threshold voltage greatly impacted the breakdown voltage. The results were obtained by applying carriers to the channels with the (001) axis perpendicular to the gate oxide. The sub-band energy profile and electron density were well implemented and derived using the Non-Equilibrium Green's Function (NEGF) formalism. Further, a few advantages of the proposed heterostructure-based DG MOSFET structure over the other structures were observed. This proposed patent design, with a reduction in the leakage current characteristics, is mainly suitable for advanced Silicon-based solid-state CMOS devices, Microelectronics, Nanotechnologies, and future-generation device applications.

Electron Mobility Enhancement of (111)-Oriented Extremely Thin Body Ge-on-Insulator nMOSFETs by Flipped Smart-Cut Substrates

Electron Mobility Enhancement of (111)-Oriented Extremely Thin Body Ge-on-Insulator nMOSFETs by Flipped Smart-Cut Substrates

Effect of Local Heat Supply into Supersonic Incoming Flow Ahead of Thin Body with Disk on Intensity of Weak Far-Field Shock Waves

Effect of Local Heat Supply into Supersonic Incoming Flow Ahead of Thin Body with Disk on Intensity of Weak Far-Field Shock Waves

Seismic sedimentology analysis of meter-scale thin sand bodies in the Jurassic Qigu Formation, Yongjin area, Junggar Basin

Seismic sedimentology is an interdisciplinary field that integrates sedimentary geology and geophysics to accurately characterize the spatial and temporal distributions of sedimentary systems. This paper focuses on the Qigu Formation in the Yongjin area of the Junggar Basin, China. The objectives are to establish a high-resolution sequence stratigraphic framework and to clarify the types of sedimentary systems present. Various technical methods, including 90° phase adjustment, attribute clustering, red-green-blue attribute fusion, stratal slicing, and seismic phase-controlled waveform indication inversion, are employed to restore the vertical evolution history of the sedimentary system and quantitatively characterize the spatial-temporal distribution of the thin sand bodies in the Qigu Formation. The results revealed that the Qigu Formation is divided into a third-order sequence, consisting of a lowstand systems tract and a lacustrine transgressive systems tract. During the lowstand systems tract, a thick channel sand body developed in the delta front, exhibiting a non-muddy, intermittent normal grading structure. The lacustrine transgressive systems tract features thin, discontinuous channel sand bodies with mud layers, also forming an intermittent normal grading structure. Two distinct types of delta fronts are identified: the first, formed during the lowstand systems tract, is characterized by branching subaqueous distributary channels in a shallow-water environment. The second, associated with the lacustrine transgressive systems tract, displays a network-like distribution of subaqueous distributary channels in a relatively deeper-water environment.

HUBUNGAN ANTARA ANEMIA DAN INDEKS MASA TUBUH IBU HAMIL TERHADAP KEJADIAN STUNTING PADA ANAK: LITERATURE REVIEW

There are many factors that cause stunting, including anemia. Pregnant women who experience anemia have a reduced oxygen supply to their body cells and brain. In general, anemia in pregnant women is caused by a lack of nutrition, a lack of iron in the food consumed, poor absorption, and chronic diseases (such as tuberculosis, lung, intestinal worms, and malaria). The body mass index of pregnant women is another cause of stunting. Mothers who are short (height <150 cm) and thin (body mass index <18.5 kg/m2) have a greater risk of birthing stunting babies than mothers who have good nutritional status. In addition to macronutrient problems, micronutrient deficiencies in pregnant women need attention. The objective of this study is to determine the relationship between anaemia and body mass index of pregnant women on the incidence of stunting in children, through a literature review. We used the literature review method with 15 journals, 10 international journals, and 5 national journals. The literature review analysis revealed a correlation between anaemia and body mass index in pregnant women and the incidence of stunting. The condition of anaemia in the mother during pregnancy will affect the metabolism of the foetus to be not optimal because there is a lack of haemoglobin levels to bind oxygen so that the adequacy of nutritional intake while in the womb is low and has an impact on foetal growth, which results in low birth weight and length. There is a relationship between anemia and pregnant women's body mass index in terms of stunting incidence.

Hubungan Tingkat Dukungan Keluarga, Pengetahuan Keluarga dan Peran Kader Terhadap Kunjungan Balita Ke Posyandu Tahun 2023

Indonesia still faces nutritional problems, one of which is undernutrition. Undernutrition is a nutritional issue that can affect toddlers. Toddlers, defined as children aged 0–59 months, need close monitoring of their growth and development since they are in the "Golden Age" phase. Toddlers experiencing undernutrition can be identified by their thin body condition, indicated by a weight-for-length or height score falling between -2 to -3 standard deviations, and/or an upper arm circumference of 11.5–12.5 cm in children aged 6–59 months. Research Objective: To determine the relationship between family knowledge, family support, and the role of health cadres in toddler visits to the integrated health post (Posyandu) at Harapan Raya Health Center. Research Contribution: While this study does not generate new theories, it is expected to contribute ideas within the field of public health. Additionally, it aims to provide researchers with insights and experience, broadening their knowledge, and serving as useful information for future studies.

Growth and Mortality Models of Mozambique Tilapia (Oreochromis mossambicus; Peters, 1852) Wildly Enter Inside the Fish Farming Ponds in Tarakan City, North Kalimantan

Graphical Abstract Highlight Research The results of this research showed that allometric growth in males and females had negative allometric growth characteristics. The growth condition index in male and female fish is dominated by thin and fat body shapes.The maximum length growth (L∞) and growth speed of males is higher than that of females. Total mortality and fishing mortality for males is higher than for females, but natural mortality for females is higher than for males. The exploitation rate of males and females is in the Under-exploitation category because the E value is <0.5. Abstract Exploring the length-weight relationship of fish and characterising growth parameters is essential in fisheries as they offer fundamental biology and population dynamics data to establish good management strategies for fisheries resources. This study examines the growth and mortality patterns of Oreochromis mossambicus. Data was collected between September and December 2022 using quantitative descriptive survey sampling. The study involved 20 repeats and deliberate random sampling of 30-50 fish per sample, emphasising total length, weight, and sex parameters. Based on 726 samples of O. mossambicus (352 fish identified as male and 374 fish identified as female). The growth model study revealed the typical negative allometric growth for both sexes (male and female). Male individuals attained a length of 33.449 cm after 37 days has a growth trend ± 0.3265 year-1, and females reached 21.150 cm in 34 days with a growth rate around 0.3135 year-1, as per the von Bertalanffy growth model. There were complex mortality patterns, with males contributing to most total deaths. This study emphasises the complex biology of tilapia and its untapped potential in the aquaculture pond system ecology in Tarakan.

Fragmented acupuncture needle as a linear metallic foreign body near the proximal interphalangeal joint of a horse.

To describe the clinical presentation, diagnosis, and treatment of a fragmented, migrating acupuncture needle near the palmar proximal interphalangeal joint (PIPJ) of a horse. A 9-year-old Warmblood cross mare. The mare presented for evaluation of a linear metallic foreign body on the palmar lateral aspect of the PIPJ following acupuncture treatment. The mare had a pinpoint puncture wound and sensitivity to palpation over the lateral aspect of the PIPJ region. The referring veterinarian performed radiographs and found a linear metallic foreign body near the lateral palmar PIPJ. Ultrasonographic examination demonstrated a hyperechoic lesion consistent with a metallic object in the soft tissues of the palmar lateral aspect of the PIPJ. The horse was anesthetized, and the linear metallic foreign body was removed. The use of intraoperative ultrasound and digital radiographs assisted in determining the location of and surgical approach to remove the foreign body. The linear metallic foreign body was the fragmented segment (body) of an acupuncture needle. The mare recovered from surgery uneventfully and returned to the previous level of activity. This report demonstrates the potential risks of prolonged retention and or delayed removal of acupuncture needles in the form of needle fragmentation and migration. It also demonstrates the use of imaging in determining the location and position of small, thin metallic foreign bodies to aid in surgical approach and removal.

Evidence of stretching/moving sheet-triggered nonlinear similarity flows: atomization and electrospinning with/without air resistance

PurposeThe purpose of this study is two-fold. First, it aims to differentiate the response of a stretching jet encountering a quadratic air resistance from the classical jet shape formed in a frictionless medium. Second, it investigates how the resulting jet forms with and without air resistance, seeking evidence that supports the similarity flows frequently studied for stretching/moving thin bodies under the boundary layer approximation.Design/methodology/approachThis study extends the established electrohydrodynamic stretching jet theory, used to model electrospinning or jet printing in the absence of air resistance, to encompass the impact of the retarding force on the jet stretching in both the cone and final regimes before it impinges on a substrate.FindingsA close examination of the nonlinear governing equations reveals that the jet rapidly thins near the nozzle because of the combined action of viscous and electrical forces. In this region, the exponentially decaying jet receives further support from the air resistance, resulting in a closer alignment with the observed experimental jet. This exponential decay, accelerated by the inversely quadratic speed of the liquid particles, serves as clear evidence for the existence of a similarity flow over an exponentially stretching sheet. Furthermore, in the final regime, the jet stretching exhibits an algebraic decay in the absence of air friction, while with air resistance, it decays exponentially to reach a limiting speed. In the former case, a square root dependence of the stretching jet speed leads to the emergence of a similarity flow over a thin stretching jet, while in the latter case, a Sakiadis’ similarity flow appears over a continuously moving flat surface.Practical implicationsThe analysis goes beyond jet hydrodynamics, delving into the interplay of electrostatic forces (including Coulomb’s law) and quadratic air drag, drawing upon experimental data on glycerol liquid presented in earlier publications.Originality/valueFinally, the asymptotic behavior of the stretching jet under the combined influence of electrostatic pull and its electric currents because of bulk conduction and surface convection is validated through a comprehensive numerical simulation of the nonlinear system.

“You started working out to get a flat stomach and a fat a$$”: A content analysis of fitspiration videos on TikTok

Fitspiration presents idealised bodies to viewers, emphasising a fit ideal to women and a muscular ideal to men. Previous content analyses have focused on images from Instagram, with research yet to examine video content on TikTok or verify the accuracy of the diet and exercise information posted by fitness influencers. This content analysis examined 200 videos from popular TikTok fitspiration hashtags (fitness, fitspo, gymtok, fittok). Two independent coders used a standardised codebook containing definitions and examples for coding. Overall, 78 % of videos showed only women, and 10 % of videos showed only men. Videos of women included both fit and thin idealised bodies, whole body and specific body part objectification, harmful themes, and promoted appearance-related reasons for exercise more frequently than videos containing men. Videos of men included muscular idealised bodies and objectification through face obscurity (excluding the face from view) more frequently than videos of women. Most videos were posted by fitness influencers, and 60 % of videos presented incorrect or harmful information. Findings suggest that fitspiration TikTok content contains characteristics known to negatively impact body image and highlights gendered differences in content themes. Further investigation is required on the promotion of appearance reasons to exercise, and the credibility of information and content creators.

Error propagation and model update analysis in three-dimensional CSEM inversion

SUMMARY This study examines error propagation from data to model space during 3-D inversion of controlled-source electromagnetic (CSEM) data using a Gauss–Newton-based algorithm. An expression for model parameter correction is obtained using higher order generalized singular value decomposition for various regularization strategies. Inverse modelling is performed for different types of noise employing distinct regularization schemes to investigate the impact of error. Data corrupted with random noise suggest that the random noise mainly propagates when regularization parameters are small, owing to the high-frequency nature of random noise. Furthermore, the random noise predominantly causes artefacts in the shallower part of the inverted model. However, it has little impact on the estimation of major anomalies because the anomaly primarily depends on the smoothly varying parts of data. These observations are valid for both isotropic and anisotropic inversions. Resistive geological anomalies, like vertical dyke or vertical fractures, may pose a significant challenge for isotropic inversion in terms of convergence and data fit, even if the subsurface is isotropic. On the other hand, anisotropic inversion performs remarkably well in such cases, showing faster convergence and better data fit than isotropic inversion. Anisotropic inversion is indispensable in the case of an anisotropic host medium, as isotropic inversion produces significant artefacts and poorer data fit. Numerical experiments suggest that, in general, anisotropic inversion produces relatively better data fit and faster convergence, even in the case of isotropic subsurface. However, due to the varying degree of sensitivity of CSEM data on thin resistive bodies, caution is required in interpreting an anisotropy obtained using anisotropic inversion. An investigation of field data also supports the observations obtained using synthetic experiments.

Seismic Prediction Technology for Channel Sand Body of Fuyu Oil Layer in Xinmin Area, Southern Songliao Basin

The Fuyu reservoir in Xinmin area is a delta plane-front facies deposit, and the channel sand body in this area is the main reservoir of oil and gas. Due to the complex sedimentary environment, the sand body shows great variation in thickness and distribution. In this study, the method of combining well vibration, model forward modeling and stratum slicing are used to predict the sandstone bodies of different thickness successfully. Especially for the thin sand body with a thickness of less than 5 meters, this study found that the GR curve can effectively distinguish sandstone and mudstone through the intersection analysis of logging curves, and applied the GR curve co-simulation inversion technology to perform fine characterization. In addition, the study also reveals that the northeastward twisting fault zone in Xinmin area is a favorable accumulation area of the reservoir, which provides a new direction for oil and gas exploration. This study not only improves the accuracy of sandstone prediction, but also provides a valuable reference for oil and gas exploration under similar complex geological conditions.

Control of blast parameters for high-quality breaking of thin slope ore bodies

Purpose. The research is aimed at substantiation of the effective method for mining thin slope ore bodies occurring in soft unstable host rocks by optimizing the breaking process, while determining the patterns of blast energy impact on the disturbed mass by explosive charges with controllable density, taking into account the geomechanical rock mass state. Methods. The research uses a comprehensive approach, including analysis of literature sources, practical experience of mining the slope ore bodies in difficult mining-geological conditions, modeling of the energy characteristics of blasts and wave action on the mass using software, as well as conducting experimental-industrial tests in the Akbakai mine. Findings. An innovative method for effective and safe ore mining from thin slope ore deposits in masses with weakened host rocks has been substantiated and developed. It implies the use of a new construction and location in the blast-holes of a charge consisting of mixed low-density explosives with widely controllable characteristics and with which the blast-holes are charged in two layers with different densities of explosives and detonated at different delay intervals. The optimum delay intervals have been determined, which improve the conditions for controlling the blast energy by changing the direction of the blast action vector towards the newly outcropped surfaces formed in the rock mass after the blasting the first stage charges. The main factors influencing the ore delivery range when mining thin slope ore bodies with blast delivery system have been revealed and methods for increasing this process efficiency are proposed. Originality. New parameters of drilling and blasting operations have been determined for the conditions of mining thin slope ore bodies of the Akbakai deposit: a rational charge construction with controllable blast characteristics has been deve-loped; the optimum range of blast-hole charging density with mixed low-density explosives and delay intervals have been substantiated; a new exponential dependence of the ore delivery range on the specific blasting agent consumption and the angle of the ore body occurrence has been revealed. Practical implications. Practical significance is in increasing the efficiency of blast breaking of minerals, improving the quality of blast delivery of broken ore to loading sites while maintaining the host rock mass continuity and reducing the ore mass dilution, eliminating the formation of large-sized pieces that complicate the blast delivery of the broken ore.