Sublayer Thickness Research Articles

Joining of SiC ceramics by iridium: The interfacial phenomena and joint strength

A methodology for joining SiC ceramic parts using iridium foil was devised. The connecting layer was formed via a solid-state reaction at 1350 °C or via a transient liquid phase (TLP) at temperatures exceeding 1417 °C. The microstructure of the connecting layer formed via solid-state reaction exhibits temporal changes. The overall thickness of the layer remains approximately constant over time; however, the thickness of the carbon-free central part, composed of Ir and iridium silicides, decreases with time. The thicknesses of the porous carbon-containing sublayers located on either side of the central region demonstrate an increase. The greatest average flexural strength value was found to be 110 ± 6 MPa. The flexural strength values decrease with an increase in the holding time. This behavior can be attributed to the growth of a porous carbon-containing layer. The connecting layer, obtained via a transient liquid phase, is composed of IrSi and C. The layers on either side of the central dense IrSi part contain a number of pores and carbon inclusions. The SiC/SiC joints formed at 1425 °C and 1500 °C exhibit bending strengths of 66 ± 4 and 29 ± 4 MPa, respectively. These findings illustrate the potential of iridium to join monolithic SiC ceramic parts at relatively low temperatures.

Macular exudate in idiopathic intracranial hypertension affects outer retina and visual acuity

BackgroundOptical coherence tomography (OCT) is suggested as a potential tool for retinal biomarkers in idiopathic intracranial hypertension (IIH). We explored how macular exudate (ME) affects retinal structure in IIH and...

Phase transition kinetics and sublayer optimization of HfO2/ZrO2 superlattice ferroelectric thin films

The sublayer thickness of superlattices, as a key factor affecting lattice integrity, interface defects, and strain, deserves in-depth studies about its impact on improving ferroelectric properties. This study described and analyzed the performance of HfO2/ZrO2 superlattices with various sublayer thicknesses. It can be concluded that the structure of the thicker layers will guide the trend of the phase composition of the entire device: when ZrO2 layers are thicker, the superlattices will exhibit antiferroelectricity due to the higher content of the tetragonal phase (t-phase); when HfO2 layers become thicker, the fraction of the monoclinic phase (m-phase) will increase, leading to a decrease in ferroelectricity and an increase in leakage current. In this way, the device with a 1:1 HfO2/ZrO2 thickness ratio was optimized to have the largest remanent polarization and the lowest leakage current. Maintaining the same thickness ratio of the HfO2/ZrO2 superlattices, it was found that HfO2/ZrO2 superlattices with thinner sublayers exhibited a larger remanent polarization (Pr) value due to increased interlayer distortion. On the contrary, the thicker sublayers reduced leakage current, which was beneficial for improving the device lifespan.

Modification of magnetoelectric properties of thin film composite multiferroics of Fe10Ni90/PVDF type with using nanostructured Fe10Ni90 layer

In this work, we study the effectiveness of using nanostructuring of a magnetostrictive Fe10Ni90 layer in a film composite multiferroic of the [Fe10Ni90/Cu]p/Fe10Ni90/PVDF type in order to obtain the maximum magnetoelectric effect (ME) while maintaining the high magnetosensitivity characteristic of thin Fe10Ni90 films. In this case, such nanostructuring parameters as the number of periods p and the thickness LFeNi of the Fe–Ni sublayers were varied. The analysis of the dependences of the ME coefficient αE on the indicated parameters carried out in this work made it possible to identify the optimal configuration of the multiferroic. Thus, the work shows that in the non-resonant mode the highest ME coupling coefficient (αE = 4.2 V/cm∙Oe) is achieved for a structure with p = 4 and LFeNi = 200 nm in a saturation field of ∼50 Oe, and a close to linear change in αE is realized in the field range 6–15 Oe. At the same time, this structure retains a low coercive field Hc ∼ 4–5 Oe and pronounced uniaxial magnetic anisotropy in the film plane. These facts indicate the absence in the magnetic component of the multiferroic structure of an undesirable “supercritical” magnetic state, which appears in unstructured Fe10Ni90 films with equivalent thicknesses of the ferromagnetic layer and sharply worsens its magnetosensitivity. Thus, in the case of a homogeneous magnetic layer, the thickness of which is equivalent to the total thickness of the magnetic phase of a nanostructured multiferroic (1000 nm), a significantly lower value of αE = 1.6 V/cm∙Oe is achieved. The totality of the data obtained indicates the validity of using the nanostructuring method when optimizing the properties of film composite multiferroics. A detailed analysis of the dependences αE(p) and αE (LFeNi) together with the results of computer modeling made it possible to determine the main factors influencing the value of αE. In particular, it is shown that an increase in αE is primarily caused by an increase in the total volume of the magnetostrictive phase in the composite, as well as a weakening of the damping effect of the substrate, which occurs with an increase in the number of periods and the thickness of individual sublayers in the structure.

Integrating Machine Learning in Geotechnical Engineering: A Novel Approach for Railway Track Layer Design Based on Cone Penetration Test Data

The cone penetration test (CPT) has emerged as a cost-effective and time-efficient method for assessing soil conditions relevant to railway track infrastructure. The geotechnical data obtained from the CPT serve as crucial input for asset managers in designing optimal sublayers and form layers for track renewal works. To properly assess the condition of soil layers, various soil behavior type charts and machine learning models based on CPT data have been published to help engineers classify soils into groups with similar properties. By understanding the properties of the soils, an optimal substructure can be designed to minimize extensive maintenance and reduce the risk of derailment. However, when analyzing multiple CPTs, the diversity and non-uniformity of subsoil characteristics pose challenges in designing a new optimal trackbed. This study presents an automated approach for recommending thicknesses of sublayers and form layers in railway tracks based on CPT data, employing machine learning algorithms. The proposed approach was tested using CPT data from the Belgian railway network and showed very good agreement with results from traditional soil investigation interpretations and layer design. A Random Forest classifier, fine-tuned through Bayesian optimization with a cross-validation technique and trained on 80% of the datasets, achieved an overall accuracy of 83% on the remaining 20%. Based on these results, we can conclude that the proposed model is highly effective at accurately designing sub-ballast layers using CPT data.

Retinal sub-layer thicknesses, presence of lacunes, and their interaction with cognitive performance in recent single subcortical infarction.

Retinal sub-layer thicknesses, presence of lacunes, and their interaction with cognitive performance in recent single subcortical infarction.

Conjugate heat transfer analysis of helium–xenon gas mixture in tight rod bundles

Helium-xenon gas mixture (He-Xe) and tight rod bundles are widely used in gas-cooled space nuclear reactors. However, few studies have been conducted on the effects of pitch-to-diameter ratio (P/D) on thermal–hydraulic characteristics while considering conjugate heat transfer. This paper numerically investigated He-Xe heat transfer in a fuel-gas gap-cladding-coolant structure of tight rod bundles. The numerical model is validated using experimental data and the maximum error of wall temperature is less than 5 %. The results show that conjugate heat transfer significantly affects the heat transfer. The heat transfer coefficient without conjugate heat transfer is only 8.85 % of that with conjugate heat transfer in the quasi-triangular pipe. The decrease in P/D enhances the convective heat transfer and causes larger pressure drops. A new performance evaluation criterion (PEC) is presented considering the effects of heat transfer, pressure drop and volume. PEC first increases and then decreases with the increase in P/D and the best comprehensive performance occurs at P/D = 1.113. The analysis of the temperature difference in the viscous sublayer (y+ < 5) shows that the decrease in P/D enhances the turbulent effect of He-Xe and reduces the thickness of the viscous sublayer, resulting in the heat transfer enhancement. This study contributes to the optimal design of advanced space reactors.

A Multilayer Doyle-Fuller-Newman Model to Optimise the Rate Performance of Bilayer Cathodes in Li Ion Batteries

Bilayer cathodes comprising two active materials are explored for their ability to improve lithium-ion battery charging performance. Electrodes are manufactured with various arrangements of lithium nickel manganese cobalt oxide Li[Ni0.6Co0.2Mn0.2]O2 (NMC622) and lithium iron phosphate LiFePO4 (LFP) active particles, including in two different discrete sub-layers. We present experimental data on the sensitivity of the electrode C rate performance to the electrode design. To understand the complex bilayer electrode performance, and to identify an optimal design for fast charging, we develop an extension to the Doyle-Fuller-Newman (DFN) model of electrode dynamics that accommodates different active materials in any number of sub-layers, termed the multilayer DFN (M-DFN) model. The M-DFN model is validated against experimental data and then used to explain the performance differences between the electrode arrangements. We show how the different open circuit potential functions of NMC and LFP can be exploited synergistically through electrode design. Manipulating the Li electrolyte concentration increases achievable capacity. Finally the M-DFN model is used to further optimize the best performing bilayer electrode arrangement by adjusting the ratio of the LFP and NMC sub-layer thickness.

Structural correlations between brain magnetic resonance image-derived phenotypes and retinal neuroanatomy.

The eye is a well-established model of brain structure and function, yet region-specific structural correlations between the retina and the brain remain underexplored. Therefore, we aim to explore and describe the relationships between the retinal layer thicknesses and brain magnetic resonance image (MRI)-derived phenotypes in UK Biobank. Participants with both quality-controlled optical coherence tomography (OCT) and brain MRI were included in this study. Retinal sublayer thicknesses and total macular thickness were derived from OCT scans. Brain image-derived phenotypes (IDPs) of 153 cortical and subcortical regions were processed from MRI scans. We utilized multivariable linear regression models to examine the association between retinal thickness and brain regional volumes. All analyses were corrected for multiple testing and adjusted for confounders. Data from 6446 participants were included in this study. We identified significant associations between volumetric brain MRI measures of subregions in the occipital lobe (intracalcarine cortex), parietal lobe (postcentral gyrus), cerebellum (lobules VI, VIIb, VIIIa, VIIIb, and IX), and deep brain structures (thalamus, hippocampus, caudate, putamen, pallidum, and accumbens) and the thickness of the innermost retinal sublayers and total macular thickness (all p < 3.3 × 10-5). We did not observe statistically significant associations between brain IDPs and the thickness of the outer retinal sublayers. Thinner inner and total retinal thicknesses are associated with smaller volumes of specific brain regions. Notably, these relationships extend beyond anatomically established retina-brain connections.

Plasma-enhanced atomic-layer-deposited HfO2–SiO2 nanolaminates for broadband antireflection coatings

The ever-increasing demand for broadband antireflection (AR) coatings has led to a growing interest in nanolaminates (NLs) with tunable properties. However, achieving excellent optical performance in NLs can be challenging due to multiple interfaces and a rather thin sublayer. In this study, we systematically investigated the factor that deteriorates the optical performance, focusing on the sublayer thickness deviation, sublayer n deviation, and interfacial diffusion, to correct the n-profiles of NLs. A pre-correction strategy for the AR coating design is proposed and experimentally demonstrated via plasma-enhanced atomic layer deposition. The excellent fit of the spectrum demonstrates that the proposed design strategy can benefit structure-sensitive NL-based coatings.

Reduced contrast sensitivity function is correlated with changes to cone photoreceptors in simple high myopia.

To investigate the contrast sensitivity function (CSF) changes in simple high myopia (SHM) and evaluate the correlations between these changes with the early changes in the retinal microstructure. This prospective study comprised 81 subjects, 20 with emmetropia (EM), 26 with low myopia and moderate myopia (LM/MM), and 35 with SHM. The area under the log CSF curve (AULCSF) and the cut-off spatial frequency (Cut-off SF) were employed as measures of CSF. Adaptive optics (AO) was employed to quantify the cone density, spacing, and regularity. The thickness and blood flow of the retinal sublayers were determined from vertical and horizontal optical coherence tomography angiography (OCTA) A-scans. Swept-source optical coherence tomography (SS-OCT) was employed to analyze the choroidal thickness (CT) and choroidal vascularity using a custom algorithm. Differences in the retinal and choroidal parameters, cone distribution, AULCSF, and Cut-off SF were compared among the three groups. Multivariate linear mixed models were used to elucidate the associations between photoreceptor morphological alterations, retinal and choroidal parameters, and AULCSF. The AULCSF and Cut-off SF were significantly lower in the SHM group compared to the EM and LM groups (p < 0.05). The SHM group had less cone density, larger cone spacing, and lower cone regularity than the EM and LM/MM groups (p < 0.05). Moreover, the thickness of the inner segment of photoreceptors (IS), retinal pigment epithelium (RPE) layer and choroid were reduced, and the outer segment of photoreceptors (OS) was thicker in the SHM group compared to the EM and LM/MM groups (all p < 0.05). A longer axial length (AL) was correlated with decreased AULCSF, cone density, and cone spacing (r = -0.800 to 0.752, all p < 0.050). Additionally, decreased CSF was correlated with lower cone density (r = 0.338, p = 0.035). Decreased contrast sensitivity was observed in patients with SHM and cone density was significantly correlated with reduced AUCSF.

Effects of thickness ratio on phase structures, mechanical properties, and wear behaviors of CrN/ZrB2 bilayer films

CrN/ZrB2 bilayer films leveraging the wear resistance of CrN and the mechanical properties of ZrB2 were successfully produced and characterized. DC magnetron sputtering was used to deposit CrN/ZrB2 bilayer films with a thickness of approximately 1 μm and various ZrB2/CrN sublayer thickness ratios (TZrB2/TCrN = 10.85, 5.78, 4.50, 2.29, and 1.04). The thickness ratio was controlled by adjusting the deposition times of the individual sublayers. The effects of thickness ratio on the films' phase structures, mechanical properties, and wear resistance were investigated. The ZrB2 sublayer initially formed with a nanocrystalline structure; as its thickness increased, its texture became (001). As the thickness of the CrN sublayer increased, the CrN (111) reflection became more dominant, and the hardness of the CrN/ZrB2 bilayer films decreased from 19.8 to 11.6 GPa. In the CrN/ZrB2 bilayer films, the CrN sublayer was softer than the harder ZrB2 sublayer; specifically, the wear rate of the monolithic ZrB2 film was 6.45 × 10−5 mm3/N·m. This hardness enabled the bilayer films to exhibit excellent wear resistance with wear rates of 1.04–1.68 × 10−6 mm3/N·m. The wear behaviors of the CrN/ZrB2 bilayer films were classified into two tribological mechanisms in accordance with wear track observations. For the samples with high TZrB2/TCrN ratios, the shear mechanism dominated the wear behavior and resulted in the formation of a transfer layer on the worn surface. By contrast, the samples with low TZrB2/TCrN ratios had a ploughing mechanism in which a deformed track was generated on the surface.

Tuning mechanical properties of TiAlSiN/TiAlN multilayers by interfacial structure

Multilayer structure as an effective way to tailor the structure and performance of hard coatings has attracted wide attentions. Here, we aim to elucidate the change of the interface, mechanical properties and oxidation resistance for TiAlSiN/TiAlN multilayers by varying modulation ratios from ML (tTiAlSiN/tTiAlN = 1:1) to HML (tTiAlSiN/tTiAlN = 1:2). Increasing TiAlN sublayer thickness stabilizes the cubic growth of TiAlSiN layers, where the HML exhibits coherent epitaxial growth in contrast to the cubic-wurtzite mixed structure of ML. This coherent strengthening effect is responsible for the noteworthy enhancement of the hardness values from ∼30.9 GPa of ML to ∼33.2 GPa of HML. Significantly, the presence of a coherent interface effectively withstands external pressure, thereby endowing HML with exceptional adhesive strength and fracture toughness. Nevertheless, the oxidation resistance of the coating is reliant on the chemical composition, with the multilayers displaying lower oxidation resistance compared to the TiAlSiN monolayer.

Charge-Transfer-Induced Interfacial Ferromagnetism in Ferromagnet-Free Oxide Heterostructures.

Due to the strong interlayer coupling between multiple degrees of freedom, oxide heterostructures have demonstrated exotic properties that are not shown by their bulk counterparts. One of the most interesting properties is ferromagnetism at the interface formed between "nonferromagnetic" compounds. Here we report on the interfacial ferromagnetic phase induced in the superlattices consisting of the two paramagnetic oxides CaRuO3 (CRO) and LaNiO3 (LNO). By varying the sublayer thickness in the superlattice period, we demonstrate that the ferromagnetic order has been established in both CaRuO3 and LaNiO3 sublayers, exhibiting an identical Curie temperature of ∼75 K. The X-ray absorption spectra suggest a strong charge transfer from Ru to Ni at the interface, triggering superexchange interactions between Ru/Ni ions and giving rise to the emergent ferromagnetic phase. Moreover, the X-ray linear dichroism spectra reveal the preferential occupancy of the d3z2-r2 orbital for the Ru ions and the dx2-y2 orbital for the Ni ions in the heterostructure. This leads to different magnetic anisotropy of the superlattices when they are dominated by CRO or LNO sublayers. This work clearly demonstrates a charge-transfer-induced interfacial ferromagnetic phase in the whole ferromagnet-free oxide heterostructures, offering a feasible way to tailor oxide materials for desired functionalities.

Effects of geometry on the thermal-fluid dynamics of a transition water flow in a square heated asymmetric cavity channel

Cavity channels candidate as a promising passive cooling configuration in thermal management. The superior performance and the limited scientific investigation regarding cavity channels dictate the need for better understanding of the thermal-fluid dynamics. To the best knowledge of the authors, there are few works investigating the effect of the geometry on the thermal-fluid dynamics of cavity channels with no focus on thermal data and quantification of the recirculation effect which can depend on geometrical parameters. In this work, numerical RANS simulations were performed in ANSYS Fluent with the kT-kL-ω turbulence model for a transitional water flow in an asymmetric square cavity channel with different attachment angles in the range of 20°–90°. The optimal heat transfer performance in terms of uniform and high Nusselt numbers is provided by the configuration with an angle in the range of approximately 30°–40°. Recirculation plays an important role in enhancing heat transfer and its strength is associated with the penetration capacity in the boundary layer. Two regions of strong and weak recirculation are identified along the channel; when the recirculation is weak, other mechanisms such as the thinning of the thermal boundary layer play a more important role. By increasing the attachment angle it is shown the local thinning of the thermal boundary layer, an augmentation of the magnitude of the negative turbulent heat flux peak, and a similarity of the conductive sublayer thickness with the recirculation strength.

Direct numerical simulations of turbulent channel flow with a rib-roughened porous wall

To describe the effects of porous roughness on turbulence, we have carried out direct numerical simulations using the lattice Boltzmann method. The simulated flows are fully developed turbulent flows in channels consisting of a solid smooth top wall and a porous bottom wall with transverse porous ribs whose heights are 10 % of the channel height. The considered ratios of the rib spacing to the rib height are $w/k\simeq 1$ and 9. The Kelvin-cell structure is applied to construct faithfully the porous media whose porosities are $\varphi \ge 0.79$ . Three kinds of porous media having different permeabilities are considered. The most permeable one has an approximately one order higher permeability than that of the least permeable one. The higher permeability case is designed to have a pore scale that is the same as the rib height so that it is the most permeable case for the rib roughness with the designed porosity. In the simulations, the bulk Reynolds number is set to $Re_b=5500$ , and the corresponding permeability Reynolds numbers are $Re_K=2.2\unicode{x2013}7.5$ . The simulated field data and the drag coefficient, which includes both the pressure drag by the ribs and the frictional drag over the porous wall, are analysed to understand the characteristics of the permeable roughness in terms of permeability. The decomposition of the drag coefficient into the integrated laminar, rib-drag, dispersion and turbulence parts elucidates the transition mechanism between the typical d-type to k-type roughness depending on $Re_K$ . By the double (time and space) averaged budget equations for the dispersion and Reynolds stresses, we explain how the energy generated by the roughness transfers to turbulence through dispersion resulting in the k-type characteristics. The nominal roughness sublayer thickness and the characteristic roughness height are introduced with the parameters obtained by fitting the velocity data to Best's and Nikuradse's logarithmic velocity formulae. Along with data in the literature, it is suggested that the ratio of the characteristic roughness height to the nominal roughness sublayer thickness becomes constant irrespective of the rib spacing in the full permeable-wall turbulence at $Re_K&gt; 7$ .

Structure and mechanical properties of TiCN-ZrCN multilayer coatings

The present study is focused on the design, deposition and characterization of nanoscale multilayer TiCN/ZrCN coatings obtained by cathodic-arc PVD technique. The multilayer coatings with the bilayer period’s thickness of 12 nm, 20 nm and 32 nm were deposited on stainless steel and high-speed steel substrates at temperature of 320°C in a mixture of N2 and CH4 gases. Scanning electron microscopy equipped with energy dispersive x-ray spectroscopy, was employed to investigate the top surface morphology, cross-sectional morphology, bilayer thickness and structure of the coatings. Mechanical properties were investigated via Calotester, Nanoindentation tester, Scratch tester and Tribometer. The SEM/EDS cross-sectional analysis revealed a columnar morphology and well expressed multi-layered periodic structure. All the multilayer samples demonstrated an increase in hardness and well fracture resistance ability in comparison to TiCN and ZrCN monolayer coatings. The highest nanohardness of 41GPa and better wear resistance for the coatings with bilayer period of 12 nm was determined. The results of the study show that a reduction in the thickness of the individual sub-layers has a significant impact on the mechanical properties of the coatings.

Periodontitis and Outer Retinal Thickness: a Cross-Sectional Analysis of the United Kingdom Biobank Cohort

PurposePeriodontitis, a ubiquitous severe gum disease affecting the teeth and surrounding alveolar bone can heighten systemic inflammation. We investigated the association between very severe periodontitis and early biomarkers of age-related macular degeneration, in individuals with no eye disease. DesignCross-sectional analysis of the prospective community-based cohort United Kingdom (UK) Biobank. ParticipantsSixty-seven thousand three hundred eleven UK residents aged 40-70 years recruited between 2006-2010 underwent retinal imaging. MethodsMacular-centered optical coherence tomography images acquired at the baseline visit were segmented for retinal sublayer thicknesses. Very severe periodontitis was ascertained through a touchscreen questionnaire. Linear mixed effects regression modeled the association between very severe periodontitis and retinal sublayer thicknesses adjusting for age, sex, ethnicity, socioeconomic status, alcohol consumption, smoking status, diabetes mellitus, hypertension, refractive error, and previous cataract surgery. Main Outcome MeasuresPhotoreceptor layer (PRL) and retinal pigment epithelium-Bruch’s membrane (RPE-BM) thicknesses. ResultsAmong 36,897 participants included in the analysis, 1,571 (4.3%) reported very severe periodontitis. Affected individuals were older, lived in areas of greater socioeconomic deprivation and were more likely to be hypertensive, diabetic and current smokers (all p<0.001). On average, those with very severe periodontitis were myopic (-0.29 ± 2.40 diopters) while those unaffected were hyperopic (0.05 ± 2.27 diopters, p<0.001). Following adjusted analysis, very severe periodontitis was associated with thinner PRL (-0.55 μm, 95% CI: -0.97, -0.12, p=0.022) but there was no difference in RPE-BM thickness (0.00 μm, 95% CI: -0.12, 0.13, p=0.97). The association between PRL thickness and very severe periodontitis was modified by age (p<0.001). Stratifying individuals by age, thinner PRL was seen among those aged 60-69 years with disease (-1.19 μm, 95% CI: -1.85, -0.53, p<0.001) but not among those under 60 years. ConclusionsAmong those with no known eye disease, very severe periodontitis is statistically associated with a thinner PRL, consistent with incipient age-related macular degeneration. Optimizing oral hygiene may hold additional relevance for people at risk of degenerative retinal disease.

Engineering Maxwell–Wagner relaxation and interface carrier confinement in Al2O3/TiO2 subnanometric laminates for high-density energy storage applications

Enhanced interface confined carrier relaxation and transport in an Al2O3/TiO2 nanolaminate, from a suitable combination of sublayer and cap layer thicknesses, is promising for high density energy storage applications.

Anatomical changes in idiopathic epiretinal membrane at 2-year follow-up assessed using spectral domain optical coherence tomography and optical coherence tomographic angiography.

To evaluate anatomical changes in the low-stage partial attachment-type idiopathic epiretinal membrane (iERM) over 2 years. Data from patients with low-stage partial attachment-type iERM (stage 2) were analyzed. The main outcome measures were anatomical changes, including changes in the foveal avascular zone (FAZ) area, vessel density (VD) in the vascular plexus, and thickness of retinal sublayers during the follow-up period. Thirty patients (mean age: 68±12 years) were included in the study. The FAZ area on the superficial vascular plexus (SVP) significantly decreased from baseline (0.12±0.08 mm2) to month 24 (0.10±0.08 mm2, p=0.024). However, the FAZ area on the deep vascular plexus (DVP) did not significantly decrease from baseline (0.15±0.13 mm2) to month 24 (0.14±0.14 mm2, p=0.099). VDs on both the SVP and DVP did not show significant change from baseline (29.51±8.14% vs. 28.35±5.63%) to month 24 (29.79±9.77%, p=0.564 vs. 28.17±5.75%, p=0.417). Parafoveal ganglion cell and inner plexiform layer (GCIPL) thickness decreased from baseline (108.77±13.61 μm) to month 24 (103.03±15.54 μm, p=0.004). The central total retinal layer thickness did not significantly change from baseline (396.07±64.86 μm) to month 24 (392.04±72.72 μm, p=0.570). Even in low-stage ERM, inner retinal changes, including GCIPL thickness, occurred during follow-up periods, which might be owing to degenerative changes or centrifugal movement.