In the work, a conjugate thermo-strength analysis was carried out for the ID-7 experimental device (ED) model. The calculation was carried out using bundles of Ansys Fluent and Static Structural programs in the Ansys Workbench environment using the Fluid-Structure-Interaction (FSI) method. The calculation of the thermal state of the ED was carried out taking into account the results of neutron-physical calculations, using the user function UDF (User Defined Function) of the Ansys Fluent program. According to the results of the non-stationary calculation, the temperature values are obtained, which vary in time and in the height of the ED. Based on the results of the thermophysical calculation, a strength calculation was carried out in the Static Structure program. Distributions of the magnitude of thermal expansion and mechanical expansion (von-Mises) in the elements of the ED are obtained.