Locating the fault position is a crucial part of the failure mechanism analysis of integrated circuits. This paper proposes a hard defect locating system based on Thermal Laser Stimulation (TLS) technology. The equation for laser-induced changes in the electrical parameters of semiconductor devices is a good guide to the hardware and software design of the hard defect locating system. The scanning mode of fast total scanning combined with slow point-to-point scanning can quickly locate abnormal areas. A modified median absolute difference (MAD) method is applied to the extraction of anomalous data. The system software can automatically and collaboratively control the 3D mobile station, laser, and signal acquisition unit. It also can intuitively display the distribution of abnormal points on the infrared image. Using a failure MRAM chip and a good one to conduct a comparative test, the abnormal points distributed on the infrared image of the chip indicate that the failure area is in the digital module or eFuse module of the chip, and the Emission Microscopy (EMMI) experiment also verifies the accuracy of the test system.