In this work, we conduct an extensive study of the asymmetric heat flow, i.e. thermal rectification, present in the two-segment Frenkel Kontorova model with both nearest-neighbor (NN) and next-nearest-neighbor (NNN) interactions. We have considered systems with both high and low asymmetry and determined that, in the weak-coupling limit, thermal rectification is larger when NNN interactions are relevant. The behavior of the heat fluxes as a function of the coupling strength between the two segments is largely consistent with a well-defined rectification for larger system sizes. The local heat fluxes present a very different behavior for systems with high and low asymmetry. The results of this work may help in the design of molecular bridges, which have recently been shown to be able to function as thermal rectification devices.