Thermal Conditions Research Articles

Effects of pH-varying thermal modification on sewage sludge: A focus on releasing nitrogen- and phosphorus-containing substances

Sewage sludge is promising for the recovery and utilisation of nutrient components, but its complex nature hinders the release of these components. The combination of pH and thermal modifications shows promise for the release of nutrient components from sludge. However, comprehensive studies on the full spectrum of pH levels and corresponding mechanisms of pH-varying thermal modification are lacking. In this study, the main nutrient components, physicochemical properties, molecular structure, and noncovalent interactions of sludge were comprehensively investigated through pH-varying thermal modification (within a pH range of 2.0 to 12.0 under the same thermal condition). The experimental results showed that the release of main organics, particularly nitrogen (N)-containing organics, was well-fitted, with a tick-like function (R2: 0.74–0.96). The thermal protons exhibited a notable accumulative mutagenic effect on the N-containing organics release, while the thermal hydroxyl ions had a more direct effect, as revealed by the changes in multivalent metals and molecular structures with the protonation–deprotonation of carboxyl groups. The driving force for the release of N-containing organics was identified as the fluctuation of electrostatic interactions at the solid–liquid interface of the sludge. However, the release of phosphorus (P)-containing substances exhibited a contrasting response to that of N-containing substances with varying pH, likely because the reaction sites of thermal protons and thermal hydroxyl ions for P-containing substances were different. Moreover, high concentrations of thermal protons and hydroxyl ions collapsed the Lifshitz–van der Waals interactions of sludge, resulting in a decrease in viscoelasticity and binding strength. These propositions were further confirmed through statistical analyses of the main indicators of the main nutrient components, physicochemical properties, and noncovalent interactions of sludge. These findings can provide a basis for optimising characteristic-specific methods to recovery nutrient components (N/P) from sludge.

Understanding the fracture mechanisms of Ni–Co–Cr-type superalloys: Role of precipitate evolution and strength degradation

Microstructure stability directly affects the performance degradation of hot-end structural parts such as turbine discs. In this research, long-term (10–10000 h) thermal exposure experiments were conducted on a Ni–Co–Cr type superalloy at 800 °C. The mechanical properties were obtained through high-temperature (750 °C) tensile tests. Subsequently, the microstructure evolution process, including intragranular γ′ and μ phases, and the initiation and propagation of defects were systematically and thoroughly studied. The results showed that intragranular γ′ precipitates coarsened under thermal exposure. After 100 h of thermal exposure, μ phases were observed near the intergranular γ′ precipitates and grain boundaries. The size and volume fraction of the μ phase initially increased, and then remained relatively stable. Numerous cracks formed on the plane of the μ phases and intergranular γ′ precipitates. With an increase in tensile stress, these cracks interconnected and propagated along the intergranular γ′ precipitates, leading to the formation of pores. Moreover, because the size of the intragranular γ′ precipitates exceeded 80 nm, the critical resolved shear stress (CRSS) was primarily activated by the Orowan bypassing mechanism. Notably, the CRSS of dislocation motion, such as stacking fault, strong-coupled shearing, and Orowan bypassing, decreased with increasing intragranular γ′ precipitate size. Therefore, the intragranular strength also weakened and the intragranular γ′ precipitates coarsened under continuous thermal conditions. This research on precipitate evolution and failure mechanisms will contribute to a better understanding of failure mechanisms for Ni–Co–Cr-based superalloys.

Identifying physiological indicators of the cognitive, thermal, and combined (cognitive-thermal) stress conditions.

Physiologically based stress detection systems have proven to be effective in identifying different stress conditions in the body to determine the source of stress and be able to counteract it. However, some stress conditions have not been widely studied, including thermal stress, cognitive stress, and combined (thermal-cognitive) stress conditions, which are frequently encountered in work or school environments. In order to develop systems to detect and differentiate these conditions, it is necessary to identify the physiological indicators that characterize each of them. The present research aims to identify which physiological indicators (heart rate, respiratory rate, galvanic skin response, and local temperature) could differentiate different stress conditions (no-stress, cognitive stress, thermal stress, and combined (thermal-cognitive) stress conditions). Thirty participants were exposed to cognitive, thermal, and combined stress sources while recording their physiological signals. The findings indicate that both mean heart rate and mean galvanic skin response identify moderate thermal and cognitive stress conditions as distinct from a no-stress condition, yet they do not differentiate between the two stress conditions. Additionally, heart rate uniquely identifies the cognitive-thermal stress condition, effectively distinguishing this combined stress condition from the singular stress conditions and the no-stress condition. Mean local temperature specifically signals thermal stress conditions, whereas mean respiratory rate accurately identifies cognitive stress conditions, with both indicators effectively separating these conditions from each other and from the no-stress condition. This is the first basis for differentiating thermal and cognitive stress conditions through physiological indicators.

Decreasing the energy demand in public buildings using nature-based solutions: case studies from Novi Sad (Republic of Serbia) and Osijek (Republic of Croatia)

BackgroundNature-based solutions (NBS) in urban areas offer an opportunity to improve environmental conditions and to reduce CO2 emissions towards establishing climate-neutral cities in the next few decades. Furthermore, the implementation of NBSs—vertical or horizontal green infrastructures on public facilities—could in particular improve both climate, including outdoor thermal conditions on a micro-scale (especially during the summer season) and the energy demand of buildings as well as save heating energy during the winter period.ResultsOn both selected buildings, extensive green roofs were implemented as an NBS intervention. The analysed data were obtained using the monitoring systems (from 2019 to 2022) installed on two public buildings in Novi Sad (Republic of Serbia) and Osijek (Republic of Croatia), with a focus on climate/bioclimate characteristics and thermal transmission capacities. Four automatic weather stations (AWS) were used for microclimate monitoring, along with the heat flow meter (HFM) method, to measure the alterations in the thermal transmittance (U value) of a flat concrete roof before and after energy refurbishment and the installation of a green roof. The outcomes of this study show that the air temperatures (Ta) and globe temperatures (Tg) near the green roof are lower by 0–3 °C for Ta and by 0–16.5 °C for Tg than the values captured by the AWSs at other locations. An even more interesting fact is that the green roof has a constant cooling potential during tropical nights, and based upon this research, the cooling value is around 2 °C for Tg (the Ta value is not distinct). The thermal transmittance results show that more savings can be achieved by applying a green roof with an 8 cm thick substrate: U values decreased by 50–69%, as measured by two different heat flux sensors.ConclusionsNature-based solutions, such as the implementation of an extensive green roof, have positive effects on diverse aspects of urban environments and building energy savings, which are particularly evident in extreme seasons, both summer and winter. Applying the proposed monitoring and assessment system could help local communities in their efforts to reduce carbon-based emissions. This paper provides a good example of the implementation of NBSs on a local- and a micro-scale.

Influence of building orientation and thermal mass configuration on the prediction of Natural Ventilation Potential (NVP) of various climates of India.

Natural ventilation potential (NVP) of a climate is a theoretical basis, and it gains importance due to the promising need for building energy conservation while conceding required thermal comfort conditions. A modified NVP analytical model is proposed by considering parameters involved in the earlier models (Yang et al., Build Environ 40:738-746, 2005; Luo et al., Build Environ 42:2289-2298, 2007). The effect of the dynamic thermal behavior of the wall/roof and building orientation on the indoor air temperature has been evaluated. The analytical model is applied to 11 major cities of India that belong to composite, hot-dry, temperate, and warm-humid climates. Five different envelope configurations are analyzed to envisage the NVP of concern climate (ED-I to ED-V). The results show that the effect of dynamic thermal response factors on the NVP is significant, and optimization of thermal response factors in addition to the U-value is mandatory. The impact of wind frequency on the selection of building orientation is substantial since it influences the total heat gained by the building envelope. Moreover, it is perceived that the optimum building orientation is independent of the climate and weather conditions. ED-II and ED-III are energy-efficient envelopes for composite, temperate, warm-humid, and hot-dry climates. The results revealed that the Mumbai climate has the highest NVP of 66% while the building is oriented in an E-W direction, and the lowest is observed for Jodhpur, i.e., 44% of the year when the building is in the NE-SW direction. The model helps the building architectural designers envisage the true NVP and assess the suitability of the building for natural ventilation.

Development and Validation of Fast and Sensitive RP-HPLC Stability-Indicating Method for Quantification of Piroxicam in Bulk Drug.

A simple, rapid, sensitive, and cost-effective green solvent-assisted reverse-phase high-performance liquid chromatographic technique, coupled with a photodiode array detector, was developed and validated for the estimation of piroxicam (PRXM). The chromatographic separation was achieved by using a C-18 (250 × 4.6) mm, 5-μm stationary phase and a mobile phase consisting of methanol and 0.1% ortho-phosphoric acid in water in a ratio of (80:20) v/v at a flow rate of 1ml/min. The detection was carried out at a wavelength of 254nm with a constant injection volume of 10μL throughout the analysis. The calibration curve was observed to be linear over the optimum concentration range of 50-300μgmL-1, with an R2 value of 0.9995. The developed method was validated as per the International Council for Harmonisation (ICH) Q2 (R1) guideline. Various parameters like selectivity/specificity, accuracy/recovery, linearity, precision, detection limit, quantitation limit, robustness and stability of analyte in solution were performed for the method validation. The PRXM was evaluated under stressed conditions, including acidic, basic, oxidative, thermal and photolytic, as per ICH Q1 (R2) guidelines. Significant degradation was observed in acidic and basic degradation conditions. Conversely, the drug substance showed stability when exposed to oxidative, photolytic and thermal degradation conditions.

High temperature co-polyester thermoplastic elastomer nanocomposites for flexible self-regulating heating devices

Pyroresistive polymer composites are smart materials with great promise in numerous fields of electronic devices, including temperature and strain sensors, self-regulating heating, and over-current/over-temperature protective devices. However, the operational window of these materials is limited by the phase transition temperatures of the polymer matrix and the brittleness of the composites. Herein, a conductive polymer composite based on a co-polyester thermoplastic elastomer reinforced with graphene nanoplatelets (GNPs) was developed, which exhibits a positive temperature coefficient (PTC) switching temperature of 200 °C. This system shows a more gradual increase in resistivity with temperature and a less pronounced drop in resistivity past the critical transition temperature than other PTC composites. Moreover, Joule heating experiments revealed the ability to regulate at a predefined maximum temperature (within 150 – 200 °C), tuneable through parameters such as filler concentration, applied voltage and thermal boundary conditions, as also demonstrated by multiphysics simulations. Due to the more gradual PTC curve, this composite can produce steady state heating far below the PTC peak, unlike almost all other PTC materials: a unique advantage for self-regulating heating devices as the polymer is not in a melt state, reducing polymer degradation, filler mobility and increasing safety margin before onset of NTC behaviour.

Thermal flow of dust particulates-laden fluid in a slanted channel subject to magnetic force, radiant heat flux, and slip and periodic thermal conditions

Thermal flow of dust particulates-laden fluid in a slanted channel subject to magnetic force, radiant heat flux, and slip and periodic thermal conditions

Effect of temperature and spawning agents on wild female asp (Leuciscus aspius) reproductive efficiency under controlled conditions

Artificial reproduction is a bottleneck to produce stocking material for many species of freshwater fish. One of these species is the asp, Leuciscus aspius. Research in the field of artificial reproduction of this species is very scarce and often incomplete. There are no breeding protocols specifying optimal environmental conditions and hormonal stimulation for many species of rheophilic cyprinids, including asp. Since the number of natural asp populations is constantly decreasing, it is important to support natural stocks by restocking with high quality stocking material. For this reason, optimized protocols are needed to breed this species under controlled conditions to produce stocking material with high biodiversity and good health. Such an approach will make it possible to maintain the population of natural asp at a constant level. The aim of this study was to develop the protocol of asp artificial reproduction using optimized thermal conditions and appropriate hormonal stimulation. In experiment I, the influence of constant temperature (10.0, 12.0 and 14.0 °C) on the effectiveness of artificial reproduction of asp. In experiment II, the effectiveness of asp reproduction was checked after the application of spawning agents: Ovopel, Ovaprim or a combination of these two agents The obtained results indicate that for the final maturation of oocytes (FOM) and artificial reproduction of asp in controlled conditions, water temperatures of 10–12 °C are the most useful. Under these thermal conditions, the highest percentages of female’s ovulation and embryo survival, as well as the percentage of hatching, were obtained. Hormone injections are necessary to perform final oocyte maturation (FOM) in female asp in captivity. All spawning agents used were especially useful for artificial reproduction of asp, however, the best values of the studied indices, such as ovulation rate and embryo survival, were obtained after the application of Ovaprim or the combination of Ovopel and Ovaprim in water temperature at a range of 10–12 °C. It was found that the pH of ovarian fluid may be a preliminary indicator of the biological quality of eggs in asps. The optimal pH value is 8.0–8.4. At pH below 7.4, no viable embryos were observed.

Evaluation of Sensitization Behaviors on the Heat-Affected Zone of Austenitic Stainless Steel Weld by Thermal Cycles of Actual Multi-pass Welding

AbstractThe sensitization behavior of the welding heat affected zone (HAZ) in austenitic stainless steels (SSs) was investigated through simulated thermal cycles emulating actual multi-pass welding processes using the Gleeble simulator. The tests were performed with austenitic SSs, considering carbon contents, heat input, and distance from the fusion line to determine the thermal cycle conditions of the HAZ. Higher carbon content led to increased sensitization (degree of sensitization, DOS) values, while the influence of the thermal cycle in the final weld pass was that even though it was rapidly heated to over 1000 °C and cooled at a rapid rate, the DOS value decreased due to partial carbide dissolution and chromium diffusion. Therefore, effective management of the final thermal cycle in the HAZ contributes to improved intergranular stress corrosion cracking resistance. Even with prolonged exposure of the HAZ to the sensitization region, the discovery that corrosion resistance improves when the final heating cycle reaches 1000 °C underscores the importance of HAZ heat cycle management and provides valuable insights for materials engineering and industrial applications. Graphical abstract

Molecular dynamics supported thermal-moisture aging effects on properties of silicone rubber

Silicone rubber materials are widely used as protective coatings in multiple fields. In this work, accelerated artificial aging tests of silicone rubber under different thermal and hygrothermal conditions were performed to better understand how temperature and humidity affected aging behavior and mechanism. It was noticed that due to the presence of oxygen molecules, the main chain of silicone rubber broke and produced free radicals, while water molecules brought hydrolysis reactions and produced silicone hydroxyl structures. Furthermore, computer aided molecular simulation was carried out to better understand the diffusion of small particles in silicone rubber materials, as well as to study how they affect the chain structure, providing support for the mechanism of aging. Finally, two lifespan prediction models were proposed respectively to determine the usage life of silicone rubber under certain temperature and humidity conditions, which provides guidance value for the use of silicone rubber.

Mixing is easy: New insights for cosmochemical evolution from pre-stellar core collapse

Signposts of early planet formation are ubiquitous in substructured young discs. Dense, hot, and high-pressure regions that formed during the gravitational collapse process, integral to star formation, facilitate dynamical mixing of dust within the protostellar disc. This provides an incentive to constrain the role of gas and dust interaction and resolve potential zones of dust concentration during star and disc formation stages. We explore whether the thermal and dynamical conditions that developed during protostellar disc formation can generate gas flows that efficiently mix and transport the well-coupled gas and dust components. We simulated the collapse of dusty molecular cloud cores with the hydrodynamics code PLUTO augmented with radiation transport and self-gravity. We used a two-dimensional axisymmetric geometry and followed the azimuthal component of the velocity. The dust was treated as Lagrangian particles that are subject to drag from the gas, whose motion is computed on a Eulerian grid. We considered 1, 10, and 100 micron-sized neutral, spherical dust grains. Importantly, the equation of state accurately includes molecular hydrogen dissociation. We focus on molecular cloud core masses of 1 and 3 $M_ odot $ and explore the effects of different initial rotation rates and cloud core sizes. Our study underlines mechanisms for the early transport of dust from the inner hot disc regions via the occurrence of two transient gas motions, namely meridional flow and outflow. The vortical flow fosters dynamical mixing and retention of dust, while the thermal pressure driven outflow replenishes dust in the outer disc. Notably, these phenomena occur regardless of the initial cloud core mass, size, and rotation rate. Young dynamical precursors to planet-forming discs exhibit regions with complex hydrodynamical gas features and high-temperature structures. These can play a crucial role in concentrating dust for subsequent growth into protoplanets. Dust transport, especially, from sub-au scales surrounding the protostar to the outer relatively cooler parts, offers an efficient pathway for thermal reprocessing during pre-stellar core collapse.

Alicyclobacillus spp. in fruit-based products: Isolation, identification, quantitative assessment (SPME/GC–MS) of spoilage compounds and spore's resistance to thermal shocks

Alicyclobacillus spp. is the cause of great concern for the food industry due to their spores' resistance (thermal and chemical) and the spoilage potential of some species. Despite this, not all Alicyclobacillus strains can spoil fruit juices. Thus, this study aimed to identify Alicyclobacillus spp. strains isolated from fruit-based products produced in Argentina, Brazil, and Italy by DNA sequencing. All Alicyclobacillus isolates were tested for guaiacol production by the peroxidase method. Positive strains for guaiacol production were individually inoculated at concentration of 103 CFU/mL in 10 mL of orange (pH 3.90) and apple (pH 3.50) juices adjusted to 11°Brix, following incubation at 45 °C for at least 5 days to induce the production of the following spoilage compounds: Guaiacol, 2,6-dichlorophenol (2,6-DCP) and 2,6-dibromophenol (2,6-DBP). The techniques of micro-solid phase extraction by headspace (HS-SPME) and gas-chromatography with mass spectrometry (GC–MS) were used to identify and quantify the spoilage compounds. All GC–MS data was analyzed by principal component analysis (PCA). The effects of different thermal shock conditions on the recovery of Alicyclobacillus spores inoculated in orange and apple juice (11°Brix) were also tested. A total of 484 strains were isolated from 48 brands, and the species A. acidocaldarius and A. acidoterrestris were the most found among all samples analyzed. In some samples from Argentina, the species A. vulcanalis and A. mali were also identified. The incidence of these two main species of Alicyclobacillus in this study was mainly in products from pear (n = 108; 22.3 %), peach (n = 99; 20.5 %), apple (n = 86; 17.8 %), and tomato (n = 63; 13 %). The results indicated that from the total isolates from Argentina (n = 414), Brazil (n = 54) and Italy (n = 16) were able to produce guaiacol: 107 (25.8 %), 33 (61.1 %) and 13 (81.2 %) isolates from each country, respectively. The PCA score plot indicated that the Argentina and Brazil isolates correlate with higher production of guaiacol and 2,6-DCP/2,6-DBP, respectively. Heatmaps of cell survival after heat shock demonstrated that strains with different levels of guaiacol production present different resistances according to spoilage ability. None of the Alicyclobacillus isolates survived heat shocks at 120 °C for 3 min. This work provides insights into the incidence, spoilage potential, and thermal shock resistance of Alicyclobacillus strains isolated from fruit-based products.

Heating and storage of medium-deep borehole heat exchangers: Analysis of operational characteristics via an optimized analytical solution model

This study focuses on investigating the thermal storage potential of medium-deep borehole heat exchanger (MDBHE) to address the issues of temperature attenuation of thermal reservoir and heating capacity reduction during the one-way heat extraction process in the heating period. By establishing an MDBHE heating system that integrates an external thermal storage source, a comprehensive analysis of the heat transfer progress and operational characteristics of the MDBHE is conducted, including optimizing burial depth, thermal storage scenarios, and aquifer conditions. The calculated solution under the typical thermal storage conditions (S60–30) in this study reveals that the average heat supply capacity increasement of a 1200 m MDBHE is 37.2 % higher than that of a 2000 m MDBHE, and the power consumption of the circulating water pump also can be reduced by 40 % in heating period. Furthermore, the enhancement of storage temperature and flow rate both contribute to a noticeable improvement in the heating performance of the MDBHE during the heating period. The heat transfer power and energy efficiency of MDBHE both increase with the elevation of seepage velocity and aquifer thickness during the energy storage and heating period. The significance of this research lies in its contribution to the enhancement of thermal storage and heat transfer efficiency in MDBHE and offering novel insights for the multi-thermal energy storage systems.

Quantification of Holocene temperatures in the eastern Hunshandake Sandy Land using δ13C of loess organic matter

The soil organic carbon isotope indicator (δ13Corg) is widely used in paleoecology and paleoclimate reconstruction due to its ability to record the history of paleovegetation change. Although it has been used as a proxy for precipitation reconstruction, increasing evidence suggests that temperature has played a crucial role in influencing the relative abundance of C3/C4 plants in the mid-latitudes during the interglacial period. This opens up the possibility of reconstructing Holocene temperature using δ13Corg. In this study, the variation of δ13Corg values in a Holocene loess profile (GLH profile), located in the eastern Hunshandake Sandy Land, China, was investigated. And we analyzed the correlation between δ13Corg values and modern temperatures for a total of 792 surface soil samples from mid-latitudes of the Northern Hemisphere, which had thermal conditions comparable to the GLH profile. Strong positive correlations were found between δ13Corg values of surface soil samples and both summer temperatures (r = 0.672, p < 0.001) and growing season temperatures (r = 0.669, p < 0.001). Additionally, δ13Corg values showed significant positive correlations with accumulated temperatures above 10 °C (r = 0.641, p < 0.001) and above 0 °C (r = 0.527, p < 0.001). However, the correlation with mean annual temperature was weak (r = 0.280, p < 0.001). The δ13Corg variation in the GLH profile recorded a mixed C3/C4 vegetation composition, with C4 plants comprising between 23.40% and 1.70% of the total abundance during the Holocene. The combined evidence from modern processes and profile variations confirms that warm-season temperature was the main factor driving variations in the δ13Corg values in the GLH profile. Therefore, we used δ13Corg–temperature conversion equations to quantify Holocene seasonal and accumulated temperatures based on the GLH profile. The reconstructed summer temperatures peaked at 9.3 ka, followed by a fluctuating downward trend during the mid- and late-Holocene, which is consistent with variations in summer solar insolation. Mean summer temperatures were relatively high at 23.3 °C and 22.5 °C in the early and mid-Holocene, respectively, while the lowest mean summer temperature of 20.5 °C occurred in the late Holocene. Accumulated temperatures above 10 °C and above 0 °C in the early Holocene were 3722 °C·d and 4641 °C·d, respectively, similar to modern observations in the Beijing area, indicating a southward shift of the temperature zone by nearly three degrees of latitude since the early Holocene. These reconstruction results are supported by modern observations, TraCE21 simulations, and other studies. This study is significant for extending the application of the δ13Corg indicator for quantitative paleoclimate reconstructions. It verifies its effectiveness in quantifying Holocene temperatures in the marginal zone of the East Asian summer monsoon.

On heat transfer in Carreau fluid flow with thermal slip: An artificial intelligence (AI) based decisions integrated with Lie symmetry

It is well accepted that non-Newtonian fluid flow narrating differential systems with thermal slip conditions at the surface plays an important role in instabilities subject to polymer extrusion like stick–slip and gross-melt-fracture instabilities. Therefore, the present article contains the artificial neural networking evaluation of the friction at magnetized porous surface having thermal and velocity slip boundary conditions. The Carrea fluid flow is mathematically formulated at a porous surface. The novelty is enhanced by considering velocity slip boundary condition, thermal slip boundary condition, chemical reaction, magnetic field, and heat generation effects. The flow differential equations are reduced by using Lie symmetry analysis. The reduced equations are solved by using the shooting method. The neural networking model is constructed by engaging 132 values of SFC. 92 (70%) is marked for training, and 20 (15%) each is marked for validation and testing. 10 number of neurons are chosen in the hidden layer. Levenberg-Marquardt algorithm is carried out to train the network. The performance of the constructed neural networking model is evaluated by MSE and R. The developed ANN is the best to predict the friction values at the magnetized porous plate. Owning to predicted values of ANN, SFC shows inciting values towards the magnetic field parameter.

Critical Factors Contributing to the Thermal Runaway of Thiophosphate Solid Electrolytes for All‐Solid‐State Batteries

AbstractAlthough all‐solid‐state batteries are suggested as a means to tackle the safety concerns associated with current Li‐ion batteries, there is presently a lack of comprehensive understanding regarding their thermal safety. In this context, critical factors contributing to the thermal runaway of thiophosphate solid electrolytes with charged Li1‐xNi0.8Co0.1Mn0.1O2 (NCM) under thermal and mechanical abuse conditions are demonstrated, considering parameters such as heating rate under thermal abuse conditions and the hybridization of S atom in structure. In particular, the thermal behavior of various solid electrolytes, including thiophosphates, thioantimonates, and halides, is investigated to clarify critical elements in Li6PS5Cl (LPSCl) contributing to its thermal instability when combined with charged NCM. Various ex situ analyses, along with density functional theory calculations, reveal a correlation between the hybridization of S atoms and the thermal instability of solid electrolytes, suggesting that sulfur acts as a key element triggering the thermal runaway of sulfide‐based solid electrolytes.

Integrated assessment of bioaerosol dispersion patterns and infection risk in a typical urban environment: Implications for urban biosecurity management

Exposure to bioaerosols in high-density urban environments will pose a severe threat to human life and health and present significant challenges to the sustainability and resilience of cities. In this study, the aerodynamic dispersion patterns of bioaerosols at two release locations (open and dense areas) under both thermal conditions in Zhongguancun, Beijing, are investigated. By coupling a dose-response model and an improved cellular automaton, the infection risk within exposed populations was assessed, and emergency evacuation strategies for distinct populations in high-risk areas were devised. This study reveals that bioaerosol distribution is notably influenced by factors such as thermal conditions, release locations and pedestrian height. Bioaerosol concentration above the release source decreases with increasing pedestrian height at two release locations. Under the same exposure time, the infection probability of different groups in this area declines with pedestrian height increases, with adult males having the highest and elderly females having the lowest probability. Thermal conditions and building layout near the release source were second only to exposure time in influencing infection probability and evacuation path. Proximity to the release source indicates a high infection probability but a short evacuation distance to safe areas, while downstream areas exhibit lower infection probability but require longer evacuation distances. The layout of buildings near the release source has the most significant effect on evacuation time. Evacuation for high-risk populations should be prioritized upstream or either side of the mainstream. This study aims to mitigate potential biological threats, address challenges in enhancing urban biosecurity management, and enable sustainable urban development.

Fabrication and evaluation of stable amorphous polymer-drug composite particles via a nozzle-free ultrasonic nebulizer

We present a promising method for producing amorphous drug particles using a nozzle-free ultrasonic nebulizer with polymers, specifically polyvinylpyrrolidone (PVP), poly(acrylic acid) (PAA), and Eudragit® S 100 (EUD). Model crystalline phase drugs–Empagliflozin, Furosemide, and Ilaprazole–are selected. This technique efficiently produces spherical polymer-drug composite particles and demonstrates enhanced stability against humidity and thermal conditions, compared to the drug-only amorphous particles. The composite particles exhibit improved water dissolution compared to the original crystalline drugs, indicating potential bioavailability enhancements. While there are challenges, including the need for continuous water supply for ultrasonic component cooling, dependency on the solubility of polymers and drugs in volatile organic solvents, and mildly elevated temperatures for solvent evaporation, our method offers significant advantages over traditional approaches. It provides a straightforward, flexible process adaptable to various drug-polymer combinations and consistently yields spherical amorphous solid dispersion (ASD) particles with a narrow size distribution. These attributes make our method a valuable advancement in pharmaceutical drug formulation and delivery.

Numerical investigation of evaporative cooling strategies on the aero-thermal performance of courtyard buildings in hot-dry climates

In hot and dry urban environments, courtyards help mitigate extreme heat and influence the urban microclimate. These structures not only provide light and private outdoor spaces but also aid in mitigating the urban heat island (UHI) effect through improved airflow and evapotranspiration. Courtyards, being central open-air areas enclosed by buildings, are crucial in creating opportunities for natural ventilation driven by wind and buoyancy-induced forces, thus serving as a microclimatic regulator. This study investigates the role of courtyards in modulating their microclimate and adjacent indoor areas by integrating evaporative cooling strategies to enhance cooling in these spaces. While numerous studies have been conducted on the role of water bodies in evaporative cooling, the aero-thermal impact on adjacent indoor spaces remains less understood. Addressing this gap, the present research explores the effect of an evaporative cooling system on the wind and thermal conditions within a courtyard and examines different natural ventilation modes, namely, single-sided and crossflow ventilation, in indoor spaces. A computational fluid dynamics (CFD) model, validated against wind tunnel experimental data, was employed to simulate various evaporative cooling water spray configurations. The results reveal complex courtyard microclimates with diverse cooling effects influenced by room orientation and floor level. Specifically, in single-sided ventilated courtyards, water sprays significantly improved the indoor thermal environment, with the average temperature across all rooms decreased by 2.06 °C, and humidity increased by 4.29 %. However, in cross-ventilated courtyards, water sprays' cooling and humidifying effects were relatively less effective. This research underscores the potential of evaporative cooling technology in improving the microclimate of courtyards, with practical applications extending to urban design and architecture. By tailoring cooling strategies to specific courtyard configurations, urban planners and architects significantly improve indoor comfort levels and energy efficiency.