Therapy In Internal Medicine Research Articles

Systemic Ozone Therapy as a complementary treatment in Internal Medicine [abstract

Systemic Ozone Therapy as a complementary treatment in Internal Medicine [abstract

Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis.

Continuous veno-venous hemofiltration (CVVH) in the treatment of severe acute pancreatitis (SAP) was investigated. A total of 60 patients with SAP treated in Affiliated Dongtai Hospital of Nantong University from October 2015 to October 2017 were enrolled in this retrospective study. Among them, 32 patients received CVVH and routine internal medicine therapy (the CVVH group), and 28 received routine internal medicine therapy (the control group). Then biochemical indexes and severity of SAP after treatment were detected to investigate the roles of CVVH and routine internal medicine therapy in treating SAP. Inflammatory factors in both the CVVH and control groups were significantly decreased after treatment (P<0.05), and CVVH could eliminate more factors. Comparison of blood biochemical indexes between the CVVH and control groups were carried out. Significant improvement was found (P<0.05) after CVVH and routine internal medicine therapy. Besides, Acute Physiology and Chronic Health Evaluation (APACHE)-II grade was significantly decreased in the CVVH group compared with that in the control group after 7 days. CVVH therapy can effectively reduce the levels of inflammatory factors in SAP patients, improve their biochemical and physiological indicators, and have high clinical application value.

Sialoblastoma in chin and management of treatment

ObjectiveSialoblastoma is a rare salivary gland tumor mainly located in parotid. In this article, we aimed to review the clinical manifestations and treatments of sialoblastoma, especially to provide effective chemotherapy regimens to instruct internal medicine therapy for unresectable or recurrent tumors. MethodWe reported a 1-year old girl who presented a left-sided firm facial mass and subsequently diagnosed as sialoblastoma. Afterwards, we reviewed and analyzed relevant literatures. ResultsSixty-four cases of pediatric sialoblastoma were reviewed. Of them, surgical excision was the basic treatment, 17 cases received chemotherapy, and 15 cases got good response. Lung metastasis was reported in six patients, all of whom had good response to chemotherapy. ConclusionChemotherapy may play an important role in residual, extensive, metastatic and relapsed cases. In addition, lung metastasis was unlikely to exert a significant effect on prognosis.

The effects of maitland orthopedic manual therapy on improving constipation.

[Purpose] This study aimed to examine the effects of interventions on constipation and to provide basic data for physical therapy in internal medicine. [Subjects and Methods] The colon transit times of 30 subjects were measured and after the interventions. Fifteen subjects were assigned to a Maitland orthopedic manual therapy group, and 15 subjects were assigned to a dietary fiber group. [Results] The analysis of changes in colon transit time showed statistically significant differences in left colon transit time, rectosigmoid colon transit time, and total colon transit time for the Maitland orthopedic manual therapy group and statistically significant differences in rectosigmoid colon transit time and total colon transit time for the dietary fiber group. An analysis of group differences in the effects of Maitland orthopedic manual therapy and dietary fiber showed that the Maitland orthopedic manual therapy group achieved statistically significantly larger declines in rectosigmoid colon transit time and total colon transit time compared with the dietary fiber group. [Conclusion] This study confirmed that Maitland orthopedic manual therapy can be an effective treatment method for internal conditions such as functional constipation by almost normalizing the colon transit time, not only by improving the symptoms of constipation but also by facilitating intestinal movements.

Status on Heart Transplantation in China.

Status on Heart Transplantation in China.

Bedeutung und Evidenz der körperlichen Aktivität zur Prävention und Therapie von Erkrankungen

A sedentary lifestyle has been shown to have negative effects on morbidity and mortality. In contrast, a large number of prospective cohort studies on the effects of regular physical activity demonstrated positive effects. Therefore, physical training is today an essential part of prevention and therapy in internal medicine. This review is based on literature research in meta-analysis and review papers. Regular physical exercise or training is a significant and evidence-based part of prevention and therapy of diseases such as heart, cardiovascular and lung diseases, diabetes mellitus, renal disease and cancer. Evidence of training effects is mostly high grade. Physical activity or exercise training is indicated in many diseases as medicine--similar as a drug. It is applied after acute treatment as a component of the standard drug therapy. There is a non-linear dose-response effect, psychological aspects and some side-effects need to be considered.In conclusion, physical exercise acts as a highly efficient drug, and should be used in many diseases. Training recommendations refer to the kind, the duration, the intensity, the frequency and the increase of training.

Optimizing the Use of Intravenous Therapy in Internal Medicine

BackgroundWe aimed to evaluate the impact of physicians' educational programs in the reduction of inappropriate intravenous lines in internal medicine. MethodsFifty-six French internal medicine units were enrolled in a nationwide, prospective, blinded, randomized controlled trial. Forms describing the patients with an intravenous line and internal medicine department characteristics were filled out on 2 separate days in January and April 2007. Following the first visit, all units were randomly assigned to either a specific education program on the appropriate indications of an intravenous line, during February and March 2007, or no training (control group). The Investigators' Committee then blindly evaluated the clinical relevance of the intravenous line according to pre-established criteria. The primary outcome was the percentage of inappropriate intravenous lines. ResultsDuring January 2007, intravenous lines were used in 475 (24.9%) of the 1910 hospitalized patients. Of these, 80 (16.8%) were considered inappropriate. In April 2007, 416 (22.8%) of the 1823 hospitalized patients received an intravenous line, which was considered in 10.2% (21/205) of patients managed by trained physicians, versus 16.6% (35/211) of patients in the control group (relative difference 39%; 95% confidence interval, −0.6-13.3; P = .05). Reduced intravenous administration of fluids, antibiotics, and analgesics accounted for the observed decrease. ConclusionThe use of a simple education program reduced the rate of inappropriate intravenous lines by almost 40% in an internal medicine setting (NCT01633307).

The impact of early rapid virological response on the outcomes of hepatitis B associated acute on chronic liver failure during antiviral treatment

To investigate the impact of early rapid virological response on the outcomes of hepatitis B associated acute on chronic liver failure during antiviral treatment. 106 acute on chronic liver failure patients in our hospital from January 2008 to July 2010 were enrolled in present study retrospectively. Besides internal medicine therapy, all patients received lamivudine (100 mg/d) or entecavir (0.5 mg/d) treatment. The profile of liver biochemistry, prothrombin time activity and viral load were detected at baseline and week 4, respectively. The patients were divided into HBV DNA negative group and HBV DNA positive group according to the viral load at week 4. The clinical features and treatment outcomes were compared between groups. Frequency variables were compared by x2 test or Fisher's exact test. Continuous variables were compared using independent samples T-test. The factors that impact on the treatment outcomes were determined using stepwise multivariate logistic regression analysis. At the week 4, the TBil and PTA in HBV DNA positive group [(261.6+/-205.6)mumol/L and 44.7%+/-19.7%, respectively] were significantly different from those in HBV DNA negative group [(160.1+/-173.4) mumol/L and 56.8%+/-23.1%, respectively] ( t = 2.190 and -2.077, respectively, P less than 0.05). The non-effective rate of HBVDNA positive group (50%, 9/18) was significantly higher than that of HBV DNA negative group (14.8%, 13/88) (x2 = 9.235, P less than 0.01). By using stepwise multivariate logistic regression analysis, the disease stage and HBV DNA undetectable at week 4 were the independent factor. The OR values of disease stage and HBV DNA undetectable were 6.559 and 0.209, respectively, and 95% CI was 2.316~18.576 and 0.058~0.747, respectively. The rapid suppression of viral load by nucleotide analogue may improve the efficacy of hepatitis B associated acute on chronic liver failure treatment. The early rapid virological response within first 4 weeks may contribute to the prediction of the treatment outcomes.

Application of receptive music therapy in internal medicine and cardiology

To investigate the effects of receptive music therapy in clinical practice. Receptive music therapy was individually applied via musical auditions, including five stages: musical stimulation, sensation, situation, reflection, and behavioral alteration. Following anamnesis and obtainment of consent, patients answered a first questionnaire on health risk evaluation (Q1), and after participating in 16 weekly music therapy sessions, answered a second one (Q2). Two men and 8 women, aged above 18 years, referred to us due to symptoms of stress, emotional suffering, and the need to change lifestyles (health risk behavior) were studied between August 1998 and December 1999. Comparison between answers to Q1 and Q2, showed a trend (P=0.059) for reduction of ingestion of cholesterol-rich foods and for increased prospects in life with a tendency towards improvement, and also of increased intake of fiber-rich food (55.6%), increased levels of personal satisfaction (44.5%), and decreased levels of stress (66.7%). The study demonstrated decreased stress levels and increased personal satisfaction, higher consumption of fiber-rich food, lower cholesterol intake, and a better perspective on life, suggesting that receptive music therapy may be applied in clinical practice as an auxiliary therapeutic intervention for the treatment of behavioral health risks.

Confirmed Clinical Efficacy of Actovegin®in Elderly Patients with Organic Brain Syndrome

A double-blind randomized clinical trial was performed comparing the therapeutic effects of Actovegin versus placebo in elderly patients with organic brain syndrome. In addition to the necessary basic internal medicine therapy, 40 geriatric patients received dialy intravenous infusions of 250 ml Actovegin 20% p.i., and 20 patients received 250 ml 0.9% saline solution as placebo over a period of four weeks. Of the patient sample, 58% were hospitalized for simple dementia (ICD-9: 290.0) and 42% due to senile dementia with depressive or paranoid symptoms (ICD-9: 290.2). Based on the Syndrome Short Test (SKT) and the Sandoz Clinical Assessment Geriatric Scale (SCAG) score, the patients suffered from mild to moderate dementia. The therapeutic effect on the total SCAG score and the Clinical Global Impression (CGI) were the primary study variables. The scores for the SCAG subscales and the SKT score served as secondary variables. The mean total SCAG score in the drug group decreased from 56.3 at the start of therapy to 36.3 points at the end of therapy, and in the placebo group the total score went from 61.2 to 52.0 (p < 0.01). The CGI showed that with Actovegin, 70% of the patients experienced "distinct improvement" or "improvement" compared to only 35% with such results in the placebo group. The SCAG subscales and the total SKT score also demonstrated the superior effects of Actovegin compared to placebo. Moreover, the therapy group treated with Actovegin showed greater improvements in social behavior and mental performance than did the placebo group.(ABSTRACT TRUNCATED AT 250 WORDS)

Current therapy in internal medicine. 3rd ed. Edited by J.P. Kassirer. Philadelphia: B.C. Decker, Inc., 1991. 1770 pp. $95

Current therapy in internal medicine. 3rd ed. Edited by J.P. Kassirer. Philadelphia: B.C. Decker, Inc., 1991. 1770 pp. $95

Current Therapy in Internal Medicine

I urge sophomore medical students, as they begin their clinical training, to develop an approach to diagnosis. Later in their careers, after making a diagnosis, they can usually up the treatment. This book is a major source of where to look it up. As the title implies, this is not a textbook of internal medicine in competition with Harrison's, Cecil , and others. It is one of 27 titles in the Current Therapy series by the same publisher. Many of the chapters on specific diseases were taken verbatim from the subspecialty books ( Current Therapy in Cardiovascular Disease, Current Therapy in Nephrology and Hypertension , and others) to constitute a volume aimed at the general internist. It is comparable in price to some of the separate subspecialty books. Readers familiar with the second edition (1987, under different editorship) will find that this is a very different and mainly improved book. The number

New Editor Named at New England Journal

THE NEW editor-in-chief of The New England Journal of Medicine (NEJM) is Jerome P. Kassirer, MD, an internist and nephrologist. Kassirer, who is the Sara Murray Jordan Professor of Medicine and Vice Chair of the Department of Medicine at Tufts University School of Medicine, and Associate Physician-in-Chief at the New England Medical Center, both in Boston, Mass, will assume his new position in July. He is the 38th person to head the journal since its start in 1812, succeeding Arnold S. Relman, MD, who announced his retirement last July after 14 years as editor. In addition to being an honored educator—he received the 1989 Alpha Omega Alpha Distinguished Clinical Science Teacher Award at Tufts—the 58-year-old Kassirer has published extensively. He is editor-in-chief of Cur- rent Therapy in Internal Medicine (3rd edition), coeditor of Clinical Problem Solving , coeditor of the Nephrology Fo-. rum , and a former NEJM editorial board member. He

Current therapy in internal medicine

Current therapy in internal medicine

Internal medicine: Current therapy in internal medicine 1984‐1985.

Internal medicine: Current therapy in internal medicine 1984‐1985.

Current Therapy in Internal Medicine, edited by T. M. Bayless, M. C. Brain and R. M. Cherniack, C.V. Mosby Company, St. Louis, 1984

Current Therapy in Internal Medicine, edited by T. M. Bayless, M. C. Brain and R. M. Cherniack, C.V. Mosby Company, St. Louis, 1984

What Is a 'Practical' Clinical Journal?

Acontrolled-circulation periodical that features reviews of diagnosis and therapy in internal medicine recently published an advertisement that declared that journals of clinical investigation offer primarily papers. There is a pejorative ring to the word research, and indeed the advertisement concludes that the practitioner will find little clinical guidance in these reports. Fortunately, not all is lost, continues the enthusiastic self-endorsement by the publishers of this nonresearch periodical, since their articles can provide practical guidance for the busy practitioner! This view is a gross misinterpretation of the functions of journals that publish original clinical studies. Are digests of current research or review articles in diagnosis and therapy the only practical articles in internal medicine? Certainly, we publish special departments with a comparable content such as GRAND ROUNDS, CLINICAL REVIEWS, and brief expositions of therapy. However, it would be a serious error to believe that the clinical investigations that comprise more

Acquired sensitivity to human albumin following albumin treatment of idiopathic hypoproteinemia.

Case Reports1 May 1954ACQUIRED SENSITIVITY TO HUMAN ALBUMIN FOLLOWING ALBUMIN TREATMENT OF IDIOPATHIC HYPOPROTEINEMIATHOMAS C. HALL, M.D., VINCENT DI RAIMONDO, M.D.THOMAS C. HALL, M.D.Search for more papers by this author, VINCENT DI RAIMONDO, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-5-1017 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince concentrated human serum albumin has become available, it has been used extensively as ideal for parenteral protein replacement, and as a plasma volume expander.1It is estimated2that to date, 2,300,000 units of 25 gm. each have been prepared in the United States according to the method of Cohn and his associates.3Although "anaphylactoid,"4pyrogenic and hemodynamic5reactions have been noted to follow intravenous injections of human serum albumin, none due to natural or acquired sensitivity has been reported. Hence the development of sensitivity after repeated administration of albumin, with the appearance of precipitins in the serum of a...Bibliography1. Janeway CA: Clinical use of products of human plasma fractionation, J. A. M. A. 126: 674-680, 1944. CrossrefGoogle Scholar2. Mulford DJ From information obtained from the Commission on Plasma Fractionation and Related Processes and from : Derivatives of blood plasma, Ann. Rev. Physiol. 9: 329-356, 1947. CrossrefGoogle Scholar3. CohnShongHughesMulfordAshworthMelinTaylor EJLEWLDJJNMHL: Preparation and properties of serum and plasma proteins, IV, J. Am. Chem. Soc. 68: 459-475, 1946. CrossrefMedlineGoogle Scholar4. Armstrong SH: Mechanisms of action of serum albumin in therapy in internal medicine, Am. J. Med. 4: 390-397, 1948. CrossrefMedlineGoogle Scholar5. Janeway CA: Plasma fractionation, Advances Int. Med. 3: 295-372, 1949. Google Scholar6. Plasma Proteins, Symposium on Nutrition of the Robert Gould Research Foundation, Volume II, 1950, C. C. Thomas, Springfield, Illinois. Google Scholar7. CohnGurdSurgenorBarnesBrownDerouauxGillespieKahntLeverLiuMittlemanMoutonSchmidUroma EJFRDMBARKGJMFWWFCHDRFKE: A system for the separation of the components of human blood: quantitative procedures for the separation of the protein components of human plasma, J. Am. Chem. Soc. 72: 465-474, 1950. CrossrefGoogle Scholar8. CohnSurgenorTullisBatchelor EJDMJLWH: The biochemistry and biomechanics of the characterization, preservation and analysis of human blood and other tissues, Academic Press, New York (to be published). Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Received for publication August 19, 1953.From the Medical Clinic of the Peter Bent Brigham Hospital and from the Medical Laboratories of the Collis P. Huntington Memorial Hospital of Harvard University at the Massachusetts General Hospital, Boston.This is publication No. 818 of the Cancer Commission of Harvard University. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHypoalbuminemia (with anasarca) due to hypercatabolism, serum protein exudation into the gastrointestinal tract, increased capillary permeability and hypoanabolism 1 May 1954Volume 40, Issue 5Page: 1017-1023KeywordsAlbuminsHospitalsHypoproteinemiaIntravenous injectionsPlasma proteinsPlasma volumeSerum albuminSerum proteins ePublished: 1 December 2008 Issue Published: 1 May 1954 PDF downloadLoading ...