: The liver and lungs are prone to be the metastatic sites of colorectal cancer. Testicular metastasis is uncommon, as is umbilical metastasis, both of them are associated with advanced disease, when they appear at the same time, it is often associated with multiple metastases and indicates poor prognosis. Here we report a 56-year-old man complained intermittent right testicular mass with scrotal pain initially. In the view of image inspection and pathological examination, he was diagnosed as stage IV transverse colon cancer with widespread metastasis according to the gastrointestinal multidisciplinary team meeting. He had received Oxaliplatin plus Capecitabine for 12 cycles, he failed to use bevacizumab for anti-angiogenesis therapy because of his economic conditions. However, revaluation for the primary and metastatic tumors were partial remission, then he received Capecitabine as maintenance therapy. The coincidence of testicular and umbilical metastasis from colorectal cancer is uncommon, and the prognosis is poor, with appropriate regimen developed by a multidisciplinary medical team used, patients with metastatic colon cancer may achieve significant benefit. We also conduct a review of the literature, the purpose is to summarize the clinical features of colon cancer metastasis to the testis and umbilical area, it is speculate that this case of metastasis may be related to transperitoneal seeding on the basis.