1. The current gold-standard method to investigate carotid atherosclerotic plaque stability is performed through histological assessment of plaque features using semi-quantitative classifications. What is the advantage of quantitative image analysis methods over traditional semi-quantitative methods for histological/pathological assessment?1A.More rapid processB.Based solely on visual estimationC.Increased inter-individual variabilityD.Improvement of pathologic interpretation biasE.Does not need manual evaluation