The prospects for the development of Arctic regions are of great interest today for the entire scientific community, in view of the strategic status of these territories. The implementation of large resource projects is impossible without preserving and developing its demographic potential. This article discusses issues related to the state and development of the demographic potential of the Arctic regions of Yakutia. The role of natural growth and migration in the formation of the population of the Arctic regions was revealed. Understanding the reasons for the outflow of the population will allow in the future to form a modern regional policy regarding the spatial development of the Arctic regions of Yakutia. The subject of the study is the demographic potential of the Yan group of districts. Interest in the group of regions under consideration is caused by a historically formed territorial production complex for the extraction of ore minerals (primarily tin and gold), as well as promising plans for the development of new deposits. The creation of energy (PATES) and transport infrastructure (Yana road, Nizhneyansk and Ust7Kuiga ports) allows us to assess the regions of the Yan group as a single promising zone for the growth of the republic’s Arctic economy. Due to the above circumstances, it becomes necessary to assess its demographic potential. The materials for the study were the official data of the territorial body of the Federal State Statistics Service for the Republic of Sakha (Yakutia), presented in annual statistical collections.