These days tumor surgery of maxillofacial region demands not just a radical removal of a tumor with primary or secondary reconstruction. Furthermore, the patient requires the full function and dental rehabilitation. To be a normal member of the society is sometimes more important for the patient than the success of radical tumorectomy and the possibility of the recurrences. Fifty-two cases (52 patients) of mandibular reconstruction using reconstruction A/O plate following composite resection of tumor masses at National Cancer Institute (NCI), Cairo University, between 1991 and 1998 were reviewed. The age of the patients was between 26-63 years. Cases were followed for 1 to 6 years and were classified into 4 groups according to location of reconstruction. Group A: Anterior mandible crossing midline (12 cases). Group B: Body segment of the mandible (14 cases). Group C: Body, ramus and condyle (20 cases). Group D: Whole mandible except both condyles (6 cases). The incidence of revision or removal of plate because of untoward complications was used as an objective measure of outcome and was calculated. The other measures are: Postoperative infection, wound dehiscence and plate exposure, tempromandibular joint pain or limited mouth opening, unsatisfactory facial contour and separation between the screw and the plate. The study concluded that reconstruction plates satisfy essential requirements of bone surgery in terms of functional stability, universal applicability and that reconstruction can provide a significant reduction of morbidity in patients with osseous defects of the mandible.