The article provides a comparative analysis of the pandemic discourse in such areas of human knowledge as philosophy, theology and academic religious studies. The philosophical discourse associated with the pandemic phenomenon aims to reflect on the relationship between the individual and the social, the personal and the political, freedom and non-freedom. Through the concept of "biopolitics" philosophy considers this concept as a factor of modern power, although at the same time the epidemic becomes the basis for seeing the Other in a special way and helping him in the current crisis situation. It has been established that in a theological context, a pandemic is not only God's punishment for the sins of ignorance, but also one of the potential options for self-improvement. Theological discourse examines not only the causes of pandemics in humanity, but also tries to understand its teleological nature in the life of every person. The situation of the pandemic creates a special direction in theology, which has already been referred to as "quarantine theology", "pandemic theology", "virus theology", or "coronavirus theology" in general. It was revealed that in academic religious studies, the phenomenon of a pandemic is revealed in the threat-challenge binary opposition. Accordingly, within the framework of this discourse, the study of the specifics of the implementation of the activities of religious organizations, the characteristics of state-confessional relations, as well as the possible consequences of epidemics is carried out. Also, religious understanding focuses not so much on the study of the causes of epidemics, diseases, etc., but focuses on highlighting the specifics of the functioning of religious organizations in such a crisis situation, the peculiarities of state-confessional relations during a pandemic, and disclosing potential consequences for the spiritual , and the laity.