The development of telehealth technology in monitoring systems has been widely used to support applications in the health sector. The aim is to provide easy access for the people. One of the implications is a real-time monitoring system based on the Internet of Things (IoT) platform. Some health vital signs that focus on observation are electrocardiogram (ECG) signal, oxygen saturation, blood pressure, and heart rate, providing heart health information. In this study, an integrated system has been implemented, namely a vital sign distributed monitoring system through the internet network. The implemented system was able to acquire vital signs then send data to the internet cloud to be stored and processed further for real-time monitoring needs by interested parties. An Android-based application called iHealthVitalSign monitor can send, process, and represent data in numerical and graphical forms. The average delay for each packet delivery was 154.73 ms and complied with the ITU-T recommendations for real-time data transfer. Heart rate (HR)detection algorithms have been evaluated on real-time ECG signals. From the test results for more than 2100 beats, the average detection accuracy is 98.78%.With this proposed application, it is hoped that it can increase the penetration of telehealth services.