Relevance. The development of innovative entrepreneurship is becoming increasingly important due to the increased level of competition in the markets of goods, works and services, the importance of solving the problems of maximum satisfaction of the needs of the population in high-quality goods and services. The success of solving these tasks depends on a number of factors, some of them act as barriers to the development of innovative entrepreneurship, some are necessary conditions. As for the first, it is important to develop measures to level and eliminate them, with regard to the second group of factors, it is important to create the conditions necessary for the fullest use of the potential of enterprises in this area.The purpose is to analyze and determine the impact and significance of regional innovative entrepreneurship, as well as to identify the prospects for the development of this sector in the Volgograd region.Objectives: to reveal the essence of the concept of "innovative entrepreneurship"; to give a forecast assessment of promising directions for the development of innovative entrepreneurship in the Volgograd region, including consideration of both the existing base and a set of measures aimed at supporting the development of this area in the region.Methodology. The method of theoretical analysis of the sources of the problem under study, the method of historical and logical analysis and assessment of the current situation, as well as the illustrative and graphic method are used.Results: the author's vision of the concept of "innovative entrepreneurship" is formulated; the key directions and measures to stimulate the development of innovative entrepreneurship in the region are identified; the main functions of the public authorities of the subjects of the Russian Federation for the development of innovative entrepreneurship in the regions are highlighted; the author's forecast assessment of the strategic prospects for the development of innovative entrepreneurship in the Volgograd region is presented; the most preferred directions for the development of innovative entrepreneurship in the Volgograd region, which require special attention from the regional public authorities, are formulated.Conclusion. The development of the Russian innovation potential is actively influenced by such factors as the state of the scientific and technical base of enterprises, sanctions restrictions, the system of state support measures.