Hybrid Renewable Energy Systems (HRES) are an attractive solution for the supply of electricity in remote areas like islands and communities where grid extension is difficult. Hybrid systems combine renewable energy sources with conventional units and battery storage in order to provide energy in an off-grid or on-grid system. The purpose of this study is to examine the techno-economical feasibility and viability of a hybrid system in Donoussa island, Greece, in different scenarios. A techno-economic analysis was conducted for a hybrid renewable energy system in three scenarios with different percentages of adoption rate (20%, 50% and 100%)and with different system configurations. Using HOMER Pro software the optimal system configuration between the feasible configurations of each scenario was selected, based on lowest Net Present Cost (NPC), minimum Excess Electricity percentage, and Levelized Cost of Energy (LCoE). The results obtained by the simulation could offer some operational references for a practical hybrid system in Donoussa island. The simulation results confirm the application of a hybrid system with 0% of Excess Electricity, reasonable NPC and LCoE and a decent amount of renewable integration.