AbstractIn the study, the focus was on evaluating the second law efficiency of a heat exchanger tube operating under continuous heat flux and turbulent flow conditions. The evaluation involved the use of a hybrid GnP and Fe3O4 and modified coiled wire as passive heat transfer enhancement techniques. The primary objective was to investigate the impact of these combined techniques on thermal and hydraulic performance, entropy generation number, Bejan number and second law efficiency. To achieve this, different mass fractions of GnP and Fe3O4 nanoparticles were used in the hybrid nanofluid, along with two forms of modified coiled wire: barrel type and hourglass type. The experimental results indicated that the utilization of hybrid nanofluids and modified helical inserts led to a noticeable improvement in the second law efficiency of the heat exchanger tube. However, it was observed that the differences in entropy generation number and Bejan number between the barrel and hourglass types were not significant, mainly due to higher frictional losses associated with the latter. The highest recorded second law efficiency was 0.416, while the lowest entropy generation number was 0.118. These values were achieved through the combined use of GnP and Fe3O4 with a mass fraction of 0.4% and a barrel-type coiled wire insert with a pitch ratio of 0.5.