Objective: To report a case of successful treatment of complete retrograde ejaculation by superovulation and intrauterine insemination (IUI), by collecting spermatozoa from post-ejaculatory urine.Design: Case report.Setting: Private infertility clinic (Harkaar Superspeciality Centre).Patient(s): A couple with primary infertility for 7 years due to male's complete retrograde ejaculation due to the congenital hypoplastic prostate gland. The woman was having subserosal fibroid but otherwise normal menstrual cycles. Intervention(s): Super-ovulation and Intrauterine insemination IUI was done after alkalinizing urine and preparing IUI sample by processing post-ejaculatory urine. IUI was done twice after HCG administration.Result(s): This protocol was used successfully to achieve pregnancy in this couple.
 Conclusion(s): To our knowledge, this is the first reported case of successful management of infertility through this protocol in Kashmir, J & K, India. This method obviates the need for more invasive sperm retrieval techniques. JMS 2016; 19(2):85-87.