Abstract
Objective: To report a case of successful treatment of complete retrograde ejaculation by superovulation and intrauterine insemination (IUI), by collecting spermatozoa from post-ejaculatory urine.Design: Case report.Setting: Private infertility clinic (Harkaar Superspeciality Centre).Patient(s): A couple with primary infertility for 7 years due to male's complete retrograde ejaculation due to the congenital hypoplastic prostate gland. The woman was having subserosal fibroid but otherwise normal menstrual cycles. Intervention(s): Super-ovulation and Intrauterine insemination IUI was done after alkalinizing urine and preparing IUI sample by processing post-ejaculatory urine. IUI was done twice after HCG administration.Result(s): This protocol was used successfully to achieve pregnancy in this couple.
 Conclusion(s): To our knowledge, this is the first reported case of successful management of infertility through this protocol in Kashmir, J & K, India. This method obviates the need for more invasive sperm retrieval techniques. JMS 2016; 19(2):85-87.
Highlights
Retrograde ejaculation is a condition in which no or minimal antegrade ejaculate is produced orgasm is present and all the sensations of ejaculation may have been experienced by the patient[1].Diagnosis is ascertained by absent or intermittent emission of ejaculate, presence of spermatozoa in post-coital urine specimen and ability to empty the bladder during erection and the presence of spermatozoa in the post coital specimen of urine [2].Retrograde ejaculation accounts for 0.3 to 2% of male infertility and is the most common cause of ejaculatory dysfunction .(2)
Without proper processing and pre-treatment, spermatozoa found in post ejaculatory urine centrifugation pellet will be almost dead and of low quality due to effects of acidic pH of urine, osmotic stress and toxicity due to urea .(1) Such spermatozoa are rendered unfit for fertilization when used in assisted reproductive techniques like intrauterine insemination (IUI)
We report a successful case of treatment of infertility due to retrograde ejaculation
Summary
Retrograde ejaculation is a condition in which no or minimal antegrade ejaculate is produced orgasm is present and all the sensations of ejaculation may have been experienced by the patient[1].Diagnosis is ascertained by absent or intermittent emission of ejaculate, presence of spermatozoa in post-coital urine specimen and ability to empty the bladder during erection and the presence of spermatozoa in the post coital specimen of urine [2].Retrograde ejaculation accounts for 0.3 to 2% of male infertility and is the most common cause of ejaculatory dysfunction .(2). Without proper processing and pre-treatment, spermatozoa found in post ejaculatory urine centrifugation pellet will be almost dead and of low quality due to effects of acidic pH of urine, osmotic stress and toxicity due to urea .(1) Such spermatozoa are rendered unfit for fertilization when used in assisted reproductive techniques like IUI
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