Objective: To explore the current research status and trend of Shenkang injection in the treatment of chronic kidney disease (CKD). Methods: By using CiteSpace6.2.R6 software, we could visually analyze the literature on Shenkang injection in the treatment of chronic kidney disease on CNKI, such as the number of documents issued, authors, institutions, keywords, and emergent word system, in order to better understand the latest research progress in this field. Results: A total of 827 relevant articles were retrieved through analysis and screening, and 663 articles were finally included after screening according to the inclusion and exclusion criteria. Through the systematic analysis, it is concluded that the number of documents issued by relevant research in this research field generally presents a good upward trend, and forms a cooperative team of authors with different numbers of members. According to the author of the document, the top three are Yunhong Wang, Yujie Hao, Yanying Lv, Sudong Tong and so on. According to the number of documents issued, the top three were Qian'an People's Hospital of Hebei Province, Beijing University of Chinese Medicine and Hebei Medical University. After analysis, 342 keywords, 8 keyword clusters, and 14 emergent words were obtained. Through the analysis of emergent words, it is concluded that "renal function", "renal failure", "adverse reactions", "alprostadil", "extracellular matrix" and "therapeutic effect" have become the research hotspots of everyone in the past 5 years. Conclusion: The research hotspots of Shenkang injection mainly focus on improving renal function, clinical therapeutic effect, adverse drug reactions and integrated traditional Chinese and western medicine. Shenkang injection has a good development trend in the treatment of chronic kidney disease, but the cooperation and sharing between different institutions need to be strengthened.
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