Presently, there is a new paradigm for pharmacy practice defined and a concept of the seven- star pharmacistgiven. The establishment of a new pharmacy system is looking for introduction and development of the electronic prescription. The aim of the study: to provide a sound research for individual pharmacies on the bases of discovering necessary financials for introduction of the electronic prescription. Results of the study: Financial aspects of the research have been evaluated by calculating payback time, ROI, NPV, and IRR. On the bases of financial calculations, the primary investment for initial costs for hardware and software has been estimated. Finally, express evaluation model for possible introduction of the electronic prescription at individual pharmacies without additional investment has been created. With the advent of information technology pharmacy has been touched with a new paradigm, which is underpinned by Introductory Handbook (2006). This handbook is devoted to and emphasized pharmacy practice approach that should be carried out by doctors, patients, and pharmacies. Necessity of new paradigm is pointed out on a Foreword of Introductory Handbook and it sounds following: Pharmacists should move from behind the counter and start serving the public by providing care instead of pills only. There is no future in mere act of dispensing. That activity can and will be taken over by the internet, machines, and/or hardly trained technicians. The fact that pharmacists have an academic training and act as health care professionals puts a burden upon them to better serve the community than they currently do. This new approach has named pharmaceutical care. On the basis of given definition International Federation (FIP) gives a key definition of pharmaceutical care. Pharmaceutical care is the responsible provision of drug therapy for the purpose of achieving definite outcomes that improve or maintain a patient's quality of life. Pharmacists, being effective health care team members, may need skills and attitudes enabling them to assume many different functions. The concept of the seven-star was introduced by World Health Organization (WHO) and taken up by FIP in 2000 in its general policy statement on Good Pharmacy Education Practice, which should cover such roles: caregiver, decision-maker, communicator, manager, life-long learner, teacher and leader. According to Introductory Handbook, term researcher is added in it as an eight's function. With the naked eye there can be able to see that, in order to realize this conception or paradigm, it should be necessary to introduce a numerous innovations in practice, which should be entailed by Information and Communications Technologies (ICT). In addition, pharmacist in his everyday work ought to be engage in management, a system, which is complicated to manage.