In simple SO(10) SUSY GUTs the top, bottom and tau Yukawa couplings unify at the GUT scale. A naive renormalization group analysis, neglecting weak scale threshold corrections, leads to moderate agreement with the low energy data. However, it is known that intrinsically large threshold corrections proportional to $\mathrm{tan}\ensuremath{\beta}\ensuremath{\sim}{m}_{t}{(M}_{Z}{)/m}_{b}{(M}_{Z})\ensuremath{\sim}50$ can nullify these t, b, \ensuremath{\tau} mass predictions. In this paper we turn the argument around. Instead of predicting fermion masses, we use the constraint of Yukawa unification and the observed values ${M}_{t},$ ${m}_{b}{(m}_{b}),$ ${M}_{\ensuremath{\tau}}$ to constrain SUSY parameter space. We find a narrow region survives for $\ensuremath{\mu}>0$ with $\ensuremath{\mu},$ ${M}_{1/2}\ensuremath{\ll}{m}_{16},$ ${A}_{0}\ensuremath{\approx}\ensuremath{-}1.9{m}_{16}$ and ${m}_{16}>1200 \mathrm{GeV}.$ Demanding Yukawa unification thus makes definite predictions for Higgs boson and sparticle masses. In particular, we find a light Higgs boson with a mass ${m}_{h}^{0}=114\ifmmode\pm\else\textpm\fi{}5\ifmmode\pm\else\textpm\fi{}3 \mathrm{GeV}$ and a light top squark with ${(m}_{{t}_{1}}{)}_{\mathrm{MIN}}\ensuremath{\sim}450 \mathrm{GeV}$ and ${m}_{{t}_{1}}\ensuremath{\ll}{m}_{{b}_{1}}.$ In addition, we find a light chargino and a neutralino LSP. It is also significant that in this region of parameter space the SUSY contribution to the muon anomalous magnetic moment ${a}_{\ensuremath{\mu}}^{\mathrm{SUSY}}<16\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}10}.$
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