In order to improve the energy efficiency, environmental protection and safety of the tank, a tank car body was designed as a prototype for the design of foam aluminum sandwich tank body. And then the static performance and Crash-worthiness of the prototype tank body were analyzed by finite element method. The mass, energy abosorption and acceleration of the main parameters of tank strength were analyzed by the MOGA method in Workbench goal-driven optimization, with the results of analysis as constraint conditions. Finally, by confirmed the optimized tank, and the results showed that the static performance and crash-worthiness of foam aluminum sandwich tank body are significantly improved and the mass is reduced, compared with the prototype structure tanker tank. which prove that foam aluminum sandwich tank body in improving the energy efficiency of tankers, environmental protection, especially the effectiveness of security.