A utism is a developmental or personality disorder, not an illness, but autism can coexist with mental illnesses such as schizophrenia and manic-depression. It shows itself in early childhood and is present throughout life; sometimes it becomes milder in old age. Nowadays it is recognised as a wide spectrum of disorders, with classical autism, where the individual is wrapped up in his or her own private world, at one extreme. It is estimated that in the United Kingdom slightly under one percent of the population, about half a million people, have a disorder on the autism spectrum The corresponding figure for other countries is not available, although it is unlikely to be very different. Autism is present in all cultures and, as far as we know, has existed for untold generations. Hans Asperger, a Viennese psychiatrist, found that some of his patients had a mild form of autism, with distinctive symptoms that later became known as Asperger’s syndrome. He was not the first to describe the syndrome but he may have been the first to recognise a connection with mathematical talent. As he observed (see Frith [13]): ‘‘to our own amazement, we have seen that autistic individuals, as long as they are intellectually intact, can almost always achieve professional success, usually in highly specialized academic professions, often in very high positions, with a preference for abstract content. We found a large number of people whose mathematical ability determines their professions.’’ Later he wrote, ‘‘It seems that for success in science or art a dash of autism is essential. For success the necessary ingredient may be an ability to turn away from the everyday world, from the simple practical, an ability to rethink a subject with originality so as to create in new untrodden ways, with all abilities canalised into the one speciality.’’ He went on to describe autistic intelligence—a kind of intelligence untouched by tradition and culture— unconventional, unorthodox, strangely pure and original. The ability to immerse oneself wholeheartedly in work or thought is something that is seen time and time again in the Asperger genius. Asperger syndrome is not the only form of autism with this connection. The Irish psychiatrist Michael Fitzgerald, for example, tells me that virtually all the people he diagnoses as autistic have an interest in mathematics. Their greatest wish, he says, is to bring the world under the control of pure reason, to create order and meaning out of the chaos that they experience around them, particularly in the puzzling social domain. Such people are naturally attracted to science, especially to the mathematical sciences, since mathematicians tend to create order where previously chaos seemed to reign. He attributes this attraction to a feeling of security that they find in the rational world of mathematics, which compensates for their inability to make sense of the mysterious social world. Much has been written about this, and the general public are now more aware of the presence of mildly autistic people in everyday life. Since I first wrote about autism in mathematicians in the Intelligencer [20] some years ago, more has been learnt about the disorder and more has been published. In this follow-up article I begin by describing research that places the link between autism and mathematical talent on a firmer footing. Then I describe some of the more recent case studies of Asperger geniuses in mathematics and associated subjects. Simon Baron-Cohen, director of the Autism Research Centre in Cambridge, has tried to put the connection on a more quantitative basis. For this purpose he devised a selfadministered questionnaire for measuring the degree to which an adult with normal intelligence has the traits associated with the autistic spectrum. From the answers to the questions a number is obtained, which he calls the autistic-spectrum quotient, providing an estimate of where a given individual is situated on the continuum from normality to autism. (Anyone who wishes to take the AQ test will easily find it by googling Simon Baron-Cohen.) When
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