Recently, designers have started using digital fabrication to create new solutions to meet global challenges. However, many technology projects in the humanitarian and development sector have been criticised for failing to deliver sustainable solutions. This study responds to these concerns by investigating the sustainability of digital fabrication projects in the humanitarian and development sector. A systems approach is used to synthesise knowledge from 14 digital fabrication projects in healthcare, education and water and sanitation. Causal loop diagrams are created to investigate the relationships between the drivers and barriers to sustainability. Several systems archetypes are also identified revealing potential leverage points for driving more sustainable solutions. The paper contextualises these findings by drawing on theories from participatory development and cosmopolitan localism. It concludes that digital fabrication presents an opportunity for more local and participatory design; however, sustainability is being undermined by a tendency to seek short-term solutions.