Disappearance Time Of Symptoms Research Articles

Effect of Cluster Nursing in Preventing Urinary Tract Infection in Postoperative Patients with Indwelling Urinary Catheter

Objective: This paper expounds and analyzes the effect of cluster nursing in preventing urinary tract infection in postoperative patients with indwelling urinary catheter. Methods: A total of 400 postoperative patients with indwelling urinary catheter, treated in Yancheng No. 1 People’s Hospital in recent two years, were recruited as research subjects. The patients were equally divided into group A and group B, with 200 patients in each group, and all received routine anti-infectives. The patients in group A (200 cases) received routine nursing. On the basis of group A, cluster nursing was implemented for patients in group B (200 cases). Results: The indwelling time of urinary catheter, the disappearance time of bladder irritation symptoms, and the probability of urinary tract infection were compared between both groups, which showed that the nursing effect of group B was better than that of group A (P < 0.05). Conclusion: The implementation of cluster nursing in postoperative patients with indwelling urinary catheter can improve the deficiency of routine nursing, consolidate the treatment effect, and reduce the complication rate of urinary tract infection.

Effect Evaluation of Artificial Intelligence-Based Electronic Health PDCA Nursing Model in the Treatment of Mycoplasma Pneumonia in Children.

The PDCA cycle, also known as Deming's cycle, mainly includes four stages: planning, implementation, inspection, and processing. As a kind of atypical pneumonia with fever and cough, mycoplasma pneumonia harms the health of many children. The purpose of this study is to investigate the anti-inflammatory and antimycoplasma effects and safety of artificial intelligence e-health PDCA nursing mode on pediatric MPP, to investigate its clinical efficacy, to observe the changes of serum cytokines (IL-10, IL-2, IL-4, IFN-γ), and to explore the mechanism of action and possible targets for the treatment of MPP, to provide a new basis for clinical treatment of MPP. The experimental results show that in the experimental group using PDCA nursing mode, the total satisfaction is 97.22%, higher than the control group of 94.44%; in the experimental group, the hospital stay and symptom disappearance time were significantly shortened by four hours. The satisfaction of nursing staff was significantly increased in statistical significance (P < 0.05). Therefore, in a statistical sense, the artificial intelligence e-health PDCA nursing mode can significantly improve the clinical symptoms of MPP children with wind-heat stagnation of lung syndrome and phlegm-heat closure of lung syndrome, improve the treatment effect of childhood mycoplasma pneumonia epidemic, shorten the time of hospitalization and symptom disappeared, and play a great auxiliary role in the treatment of childhood mycoplasma pneumonia.

Effect of Tiaojingzhixue Fang on the expression of sex hormone and endometrial tissue mRNA in perimenopausal patients with abnormal uterine bleeding.

This study aimed to investigate the effect of Tiaojingzhixue decoction on the expression of sex hormone and endometrial mRNA in perimenopausal patients with abnormal uterine bleeding. For this purpose, 84 patients with perimenopausal abnormal uterine bleeding who were treated in our hospital from January 2018 to January 2019 were divided into study group and control group, the control group was treated with mifepristone for six months, the clinical efficacy, time of symptom relief and disappearance, endometrial thickness, menstrual volume, adverse events, expression of sex hormone (ER), Progesterone receptor (PR), Lutropin (LH), Follicle-stimulating hormone (FSH), Estradiol (e2) and Vascular endothelial growth factor in endometrial tissue were compared between the two groups. The results showed that the clinical efficacy of the study group (97.61%) was significantly higher than the control group (80.95%) (P<0.05). There was no significant difference in endometrial thickness between the two groups before treatment, but after treatment for 1 month, 3 months and 6 months, endometrial thickness was thinner in the study group (P<0.05). There was no significant difference in menstrual volume between the two groups before treatment (P <0.05), but it was lower in the study group (P <0.05). The incidence of adverse reactions in the study group was 11.90% lower than in the control group (26.19%). The expression levels of ER, PR, LH, FSH and E2 were almost the same before treatment and there was no significant difference between the two groups (P>0.05), but they were lower in the study group after treatment (P<0.05). Before treatment, there was no significant difference in the level of VEGF between the two groups (P>0.05); after treatment, the level of Vegf in the study group was lower than the control group (P<0.05). After treatment, the level of Vegf in both groups was significantly higher than before treatment (P<0.05). In general, Tiaojingzhixue decoction can decrease the level of sex hormone and increase the expression of VEGF in patients with perimenopausal abnormal uterine bleeding.

Clinical Symptoms and Quality of Life Improvement Value of Ornidazole Mixture in Auxiliary Filling Treatment of Patients with Endodontic Disease

To evaluate the clinical effect of ornidazole mixture in auxiliary filling of patients with endodontic disease. A total of 124 patients with endodontic diseases admitted to our hospital from January 2020 to December 2021 were included and divided into two groups according to the random number table. The observation group (n = 62) was given ornidazole mixture-assisted filling, while the control group (n = 62) was given pulp mummification filling to evaluate its application effect. Compared with the control group, the disappearance time of tooth hyperesthesia, gingival redness, and pain symptoms in the observation group were significantly shorter and the difference had statistical significance (P < 0.05); the excellent and good rate of the observation group was 96.77% and 85.48%, respectively, and the difference had statistical significance (P < 0.05); the masticatory efficiency, occlusal force, and oral health-related quality of life scores in the observation group were higher than those in the control group after treatment, and the difference had statistical significance (P < 0.05). Ornidazole mixture can promote the curative effect, shorten the time of symptom disappearance, and effectively improve the masticatory function and quality of life in patients with endodontic diseases.

Analysis of Clinical Efficacy of Erythromycin Combined with Oseltamivir Phosphate Granules in the Treatment of Mycoplasma Pneumonia in Children

We attempt to discuss the improvement of clinical efficacy of erythromycin combined with oseltamivir phosphate granules in children with mycoplasma pneumonia and its influence on lung function and infection indicators. We selected 60 patients with mycoplasma pneumonia in children from February 2019 to June 2020 and randomly divided them into observation group (30 cases of erythromycin combined with oseltamivir phosphate granules) and control group (oseltamivir phosphate) Wei granule treatment (30 cases), compare the clinical effective rate, changes in various indicators of lung function, disappearance time of clinical symptoms and changes in serum procalcitonin, C-reactive protein and interleukin 6 concentration levels in both groups before and after treatment. Observation group possessed remarkably higher ratio of time to peak tidal expiratory flow to total expiratory time, ratio of instantaneous velocity to tidal peak expiratory velocity at 75 % tidal volume and tidal volume than control group (p<0.05); and it had remarkably lower antipyretic time, rales disappearance time, throat and tonsil hyperemia disappearance time than control group (p<0.05); observation group possessed remarkably lower length of stay than control group (p<0.05) and procalcitonin, interleukin 6 and C-reactive protein concentration in serum of observation group declined more than control group (p<0.05). The total clinical effective rate of observation group (93.4 %) was remarkably higher than control group (80 %) (p<0.05). Erythromycin combined with oseltamivir phosphate particles can remarkably improve the clinical effectiveness of mycoplasma pneumonia in children, improve lung signs and clinical effectiveness and reduce procalcitonin, C-reactive protein and interleukin 6 concentration in serum. Effective treatment of pneumonia provides clinical guidance value.

Effects of health education based on mobile platform on cognitive function and quality of life of children with pneumonia

Objective: To explore the effects of health education based on mobile platform on cognitive function and quality of life of children with pneumonia. Methods: Eighty parents with pneumonia admitted to our hospital from March 2018 to March 2020 were selected as the research subjects. The parents of the control group received routine nursing intervention, and the parents of the observation group received health education intervention based on the mobile platform. After nursing, the nursing effect of the two groups was compared. The cognitive function and quality of life of the two groups were compared after nursing. The time of cough, dyspnea, shortness of breath and lung rales were compared between the two groups. The incidence of rash, abdominal pain, dizziness and headache and parents' satisfaction with nursing were compared between the two groups. Results: Compared with the control group, the nursing effective rate of the observation group was significantly increased (P&lt;0.05). The scores of cognitive function and quality of life in observation group were significantly higher than those in control group (P&lt;0.05). Compared with the control group, the disappearance time of clinical symptoms in the observation group was significantly decreased (P&lt;0.05). The satisfaction of parents in the observation group was significantly higher than that in the control group (P&lt;0.05). Conclusion: Health education based on mobile platform can effectively improve the cognitive function and quality of life of children with pneumonia, contribute to the early recovery of children, and has high clinical application value.

Difference between Acyclovir and Ganciclovir in the Treatment of Children with Epstein-Barr Virus-Associated Infectious Mononucleosis.

Objective To investigate the efficacy differences between acyclovir and ganciclovir in the treatment of children with Epstein–Barr virus (EBV)- associated infectious mononucleosis (IM). Methods A total of 128 children with EBV-IM who were admitted to our hospital from February 2019 to February 2021 were selected and randomly divided into the acyclovir group (n = 64) and the ganciclovir group (n = 64) according to the random number table method. All the children were given symptomatic treatments such as protecting the liver and reducing fever. On this basis, the acyclovir group was given an intravenous drip of acyclovir, while the ganciclovir group was given an intravenous drip of ganciclovir. The treatment was continued for 7 days. After the treatment, the clinical efficacy, disappearance time of symptoms and signs, related blood routine indexes, EBV-DNA negative conversion rate, and the incidence of adverse reactions during the treatment were compared between the two groups. Results After treatment, the total effective rate of the ganciclovir group (92.19%) was higher than that of the acyclovir group (73.44%) and the difference was statistically significant (P < 0.05). The disappearance time for the symptoms and signs of angina, fever, lymphadenopathy, hepatomegaly, and splenomegaly in the ganciclovir group was lower than that in the acyclovir group, and the difference was statistically significant (P < 0.05). After treatment, the levels of atypical lymphocyte proportion, lymphocyte proportion, and WBC count in the two groups were lower than those before treatment, the levels in the ganciclovir group were lower than those in the acyclovir group, and the difference was statistically significant (P < 0.05). After treatment, the EBV-DNA negative conversion rate (81.25%) in the ganciclovir group was higher than that in the acyclovir group (60.93%) and the difference was statistically significant (P < 0.05). During treatment, the incidence of adverse reactions in the ganciclovir group was significantly lower than that in the acyclovir group and the difference was statistically significant (P < 0.05). Conclusion In the treatment of children with EBV-IM, the therapeutic effect of ganciclovir is obviously superior to that of acyclovir. Ganciclovir can quickly eliminate the symptoms of angina, fever, enlarged lymph nodes, and other signs in children, can improve abnormal blood indicators, and has a higher negative conversion rate of EBV and less adverse reactions.

The therapeutic effects of naringenin on bronchial pneumonia in children.

Bronchial pneumonia in children is a common infectious disease in toddlers and infants, which may cause hyperpyrexia, pulmonary moist rales, and even respiratory failure. Traditional drugs for bronchial pneumonia in children often lead to drug resistance and side effects. Recently, naringenin has been reported to be a potential treatment for several airway inflammatory diseases due to its anti‐inflammatory and anti‐microbial activities. The current clinical study aimed to evaluate the safety and therapeutic effect of naringenin in treating bronchial pneumonia in children. A total of 180 eligible patients were randomly assigned into naringenin (NAR) group and azithromycin (AZI) group. All participants were required to follow a 5‐day oral administration, and their serum cytokine levels were measured during the clinical intervention. After the treatment, the disappearance time of clinical symptoms, and the incidences of complications and adverse reactions were compared between the two groups. Naringenin was able to inhibit inflammation, shorten the disappearance time of clinical symptoms, reduce the incidences of bronchial pneumonia complications and related adverse reactions, and improve the health conditions of the patients. Our results suggested that naringenin was safe and beneficial to children with bronchial pneumonia, providing new insights into the clinical application of naringenin.

Preventive and therapeutic significance of octreotide combined with lansoprazole on post-ERCP pancreatitis and its effect on serum amylase, inflammatory factors and immune function.

The study aimed to investigate the preventive and therapeutic significance of octreotide combined with lansoprazole on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) and its effects on serum amylase (AMS), inflammatory factors and immune function. A total of 132 patients who underwent ERCP in Shaoxing People's Hospital (Shaoxing, China) were enrolled in the study and allocated into two groups: The study group (octreotide plus lansoprazole, 68 cases) and the control group (octreotide alone, 64 cases). The incidence of PEP and post-ERCP hyperamylasemia (PEH), the concentrations of serum AMS, interleukin-17 (IL-17) and tumor necrosis factor-α (TNF-α), as well as the T-lymphocyte population in peripheral blood were detected. The AMS levels in the study group were significantly lower than those in the control group at 6 and 24 h after treatment (P<0.001). The incidence of PEP and PEH, symptom disappearance time and hospital stay in the study group were significantly lower than those in the control group after treatment (P<0.05). The levels of IL-17 and TNF-α in the study group were significantly lower than those in the control group after treatment (all P<0.05). The percentage of CD3+, CD4+, CD8+ cells and the ratio of CD4+/CD8+ in the study group were significantly higher than those in the control group after treatment (all P<0.05). The results indicated that octreotide combined with lansoprazole reduces AMS levels and the incidence of PEP, alleviates inflammation and improves the immune function.

Observation on Shao's five-needle therapy as adjuvant treatment for stroke-associated pneumonia

To compare the therapeutic effect between Shao 's five-needle therapy combined with conventional western medical treatment and the simple conventional western medical treatment on stroke-associated pneumonia. A total of 80 patients were randomized into an observation group and a control group, 40 cases in each group. Conventional western medication treatment i.e. anti-infection combined with rehabilitation swallowing training were adopted in the control group. On the basis of the treatment in the control group, Shao 's five-needle therapy was applied at Feishu (BL 13), Dazhui (GV 14), Fengmen (BL 12), etc. in the observation group, once a day. The treatment was given for 10 days in the both groups. The levels of inflammatory indexes [white blood cell (WBC), C-reactive protein (CRP), percentage of neutrophil (N%)] before and after treatment, the disappearance time of main clinical symptoms and signs, the scores of National Institutes of Health Stroke scale (NIHSS) and the ability of daily living (ADL) were observed, and the clinical therapeutic effect was evaluated in the both groups. Compared before treatment, the levels of WBC, CRP, N% and the NIHSS scores after treatment were decreased (P<0.05), the ADL scores were increased in the both groups (P<0.05), and the improvement of above indexes in the observation group was superior to the control group (P<0.05). The recovery time of temperature and rale, the duration of cough in the observation group were shorter than those in the control group (P<0.05). The effective rate was 97.5% (39/40) in the observation group, which was superior to 85.0% (34/40) in the control group (P<0.05). Shao 's five-needle therapy combined with conventional western medical treatment can effectively improve the clinical symptoms in patients with stroke-associated pneumonia, down-regulate the inflammatory indexes and improve the quality of life, the therapeutic effect is superior to the simple conventional western medical treatment.

Efficacy of inhaled budesonide on serum inflammatory factors and quality of life among children with acute infectious laryngitis

ObjectiveAcute infectious laryngitis is commonly occurred among children. Our study sought to investigate the effect of inhaled budesonide on among children with acute infectious laryngitis. MethodsA total of 92 children with acute infectious laryngitis were randomly allocated to either the study (46 cases, treated with inhaled budesonide) and control group (46 cases, treated with dexamethasone). The disappearance time of symptoms, therapeutic effect and adverse reactions were observed in the two groups. ResultsThe therapeutic effect was significantly better in the study group than in the control group (97.83% vs 82.61%). After 3 days of treatment, the disappearance time of symptoms, such as hoarseness/barking cough, singing sound in the throat, three-concave sign and dyspnea in the study group was significantly less than that in the control group (P < 0.05). The levels of IL-4, IL-17, MMP-9, IL-33, IFN-γ and IgE in the two groups decreased, and evidently lower levels were found in the study group as compared to the control group (P < 0.05). ConclusionInhaled budesonide exerted obvious better effect in terms of reducing serum inflammatory factors and improving the quality of life with safety profile.

Comparison of the efficacy of ambroxol hydrochloride and N -acetylcysteine in the treatment of children with bronchopneumonia and their influence on prognosis.

The aim of the present study was to compare the efficacy of ambroxol hydrochloride and N-acetylcysteine in the treatment of children with bronchial pneumonia and their influence on prognosis. A total of 120 children with bronchial pneumonia, admitted to The Affiliated Yantai Yuhuangding Hospital of Qingdao University from July 2015 to August 2018, were enrolled in the study. Among them, 58 children were treated with N-acetylcysteine and comprised the experimental group, and 62 children were treated with ambroxol hydrochloride and comprised the control group. Children's physical signs (such as fever, short breath, cough and pulmonary rales) and the adverse reactions to treatment were observed, and the disappearance time of the signs was recorded. In addition, the cellular immune function indicators and the quality of life after treatment were investigated. There was no significant difference in clinical data between the two groups (P>0.05). The effective rate in the experimental group was significantly higher than that in the control group (P<0.05). The disappearance time of symptoms, such as fever, cough, asthma and rales in the lung, was significantly shorter in the experimental group than that in the control group (P<0.05). The hospitalization time of patients in the experimental group was shorter than that in the control group (P<0.05). After treatment, immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM) and complement C3 were significantly increased in the experimental group (P<0.01), and the IgA and IgG in the experimental group were significantly higher than those in the control group (P<0.01). The incidence of adverse reactions in the experimental group was significantly lower than that in the control group (P<0.05). In conclusion, N-acetylcysteine has a significant effect on the treatment of bronchopneumonia in children providing a quick relief from symptoms, such as lung rales, and therefore is worthy of use in clinic.

Comparison of clinical efficacy of dydrogesterone and progesterone in the treatment of threatened abortion

Objective To compare the clinical effect of dydrogesterone and progesterone in the treatment of threatened abortion. Methods From March 2015 to May 2017, 50 patients with threatened abortion admitted in the Maternal and Child Health Hospital of Ninghai County were selected and randomly divided into two groups according to the digital table, with 25 cases in each group.The control group was treated with progesterone.The observation group was treated with dydrogesterone.The hormone levels, symptom disappearance time, fetal retention and adverse drug reactions were compared between the two groups. Results One week after treatment, the levels of progesterone, estradiol and human chorionic gonadotropin in the observation group were (1 12.65±6.35)nmol/L, (2 137.99±371.22)pmol/L, (4 261.54±245.55)IU/L, respectively, which in the control group were (101.56±5.32)nmol/L, (1 782.12±350.71)pmol/L, (3 642.26±210.20)IU/L, respectively, the differences between the two groups were statistically significant (t=6.694, 3.484, 9.581, all P 0.05). Conclusion The effect of dydrogesterone in the treatment of threatened abortion is better than progesterone. Key words: Abortion, threatened; Progesterone; Dydrogesterone; Receptors, progesterone; Estradiol; Chorionic gonadotropin; Drug therapy; Comparative study

Effect of Xiaoerfeire Kechuan Granule in the treatment of children with bronchopneumonia and its effect on serum APC and IL-1R

Objective To observe the effect of Xiaoerfeire Kechuan Granule in the treatment of bronchopneumonia in children and its effect on serum activating protein(APC) and interleukin-1 receptor(IL-1R). Methods From June 2016 to June 2018, 116 children with pediatric bronchial pneumonia admitted to the Maternal and Child Health Hospital of Lishui were selected as observation subjects.According to the random number table method, the patients were divided into observation group and control group, with 58 cases in each group.Both two groups were given conventional therapy.On the basis of this treatment, the observation group was treated with Xiaoerfeire Kechuan Granule.The therapeutic effects, the disappearance time of clinical symptoms, and the changes of APC and IL-1R levels before and after treatment were observed. Results After treatment, the total effective rate of the observation group was 96.55%, which was higher than that of the control group(81.03%), the difference was statistically significant(χ2=7.017, P=0.008). The defervescence time, lung voice disappeared time, disappearance time of X-ray inflammation and disappearance time of cough in the observation group were shorter than those in the control group, and the differences were statistically significant(t=9.134, 13.157, 3.407, 8.532, all P 0.05). After treatment, the serum ACP levels increased in both two groups(all P<0.05), and the ACP level of the observation group was higher than that of the control group(t=5.209, P<0.05); the serum IL-1R level of the two groups were decreased(all P<0.05), and the IL-1R level of the observation group was lower than that of the control group (t=11.835, P<0.05). Conclusion Xiaoerfeire Kechuan Granule is effective in the treatment of children with bronchopneumonia, which can improve the clinical symptoms of children rapidly, its mechanism may be related to lowering serum IL-1R level and increasing APC level. Key words: Xiaoerfeire Kechuan Granule; Bronchial pneumonia; Integrated Chinese and western medicine therapy; activating protein; IL-1R; Efficacy; Improve symptoms

Effects of detail nursing in septic shock patients

Objective To explore the effects of detail nursing in septic shock patients. Methods From January 2017 to June 2018, we selected 70 septic shock patients at West China Hospital of Sichuan University by convenience sampling. All patients were divided into control group (n=35) and observation group (n=35) with the method of random number table. Control group carried out routine nursing. On the basis of that in control group, observation group implemented detail nursing for two weeks. We compared the clinical effects, hemodynamics, health condition and the score of Glasgow coma scale (GCS) of patients between two groups before and after intervention. Results The effective rate of treatment of septic shock patients in observation group was 88.57% higher than that (65.71%) in control group with a statistical difference (P<0.05) . The hospitalization time, time using ventilator, time of consciousness recovery, disappearance time of symptoms and signs of observation group were shorter than those of control group; the serum C-reactive protein of observation group was lower than that of control group; the differences were all statistical (P<0.01) . After intervention, the cardiac index, mean arterial pressure, venous oxygen saturation of patients in observation group were higher than those in control group; the heart rate of patients in observation group was lower than that in control group; the differences were all statistical (P<0.05) . After intervention, the score of health condition of patients in observation group was lower than that in control group; the score of GCS of patients was higher than that in control group; the differences were all statistical (P<0.05) . Conclusions Detail nursing for septic shock patients can improve the quality of life of patients and has a little influence on hemodynamics which is worthy of clinical generalization and application. Key words: Nursing care; Shock, septic; Hemodynamics; Recovery

Value of ambroxol in the treatment of asthmatic bronchitis.

Objective:To investigate the clinical effect of ambroxol in the treatment of asthmatic bronchitis.Methods:One hundred and twenty patients with asthmatic bronchitis who were admitted to our hospital from June 2017 to August 2018 were selected as the research subjects and divided into a control group and an observation group according to random number table method, 60 in each group. The control group was treated with conventional treatment, while the observation group was treated with ambroxol in addition to conventional treatment. The therapeutic effect, disappearance time of symptoms and signs and the recovery of pulmonary function were compared between the two groups.Results:The total effective rate of the observation group was 96.7%, and that of the control group was 73.3%. The control effect of the observation group was significantly better than that of the control group, showing a significant difference (P<0.05). The disappearance time of symptoms of the observation group was shorter than that of the control group, and the recovery of pulmonary function was better; the differences were statistically significant (P<0.05).Conclusion:For asthmatic bronchitis patients, addition of ambroxol to conventional treatment can improve the therapeutic effect, shorten the disappearance time of clinical signs and symptoms, and promote the recovery of patients, which is worth clinical application.

Comparison of azithromycin and erythromycin in the treatment of mycoplasma pneumonia in children.

Objective:To study and compare the clinical effects of azithromycin and erythromycin on children with mycoplasma pneumonia.Methods:Total 132 children with mycoplasma pneumonia who were admitted to our hospital between November 2017 and September 2018 were selected as the research subjects. All the children were divided into an observation group and a control group according to random number table, 66 each. The observation group was treated with azithromycin, while the control group was treated with erythromycin. The therapeutic effect, incidence of adverse reactions and disappearance time of clinical symptoms were compared between the two groups.Results:The total efficacy of the observation group was 98.04%, and that of the control group was 74.51%; there was a significant difference (X2=7.184, P=0.007). The incidence of adverse reactions in the observation group was 15.69%, significantly lower than that in the control group (41.18%) (X2=6.376, P=0.002). The disappearance of fever, cough, rale and X ray shadow of the observation group was significantly earlier than that of the control group, and the difference was statistically significant (P<0.05).Conclusion:Compared with erythromycin, azithromycin is more effective in the treatment of mycoplasma pneumonia in children. Azithromycin can further shorten the improvement time of clinical symptoms and signs and has few adverse reactions and high safety. It is worth clinical application.

Meta-analysis of randomized controlled trials on effect of Tanreqing Injection combined with Western medicine on acute exacerbation of chronic bronchitis

To systematically review the effectiveness and safety of Tanreqing Injection in treating acute exacerbation of chronic bronchitis( AECB). CNKI,Wan Fang,VIP,CBM,Medline,Cochrane Library,EMbase and Web of Science were retrieved,and randomized controlled trials for the effect of Tanreqing Injection in the treatment of acute exacerbation of chronic bronchitis were screened. The quality of the included studies was evaluated according to the Cochrane Handbook&apos;s evaluation criteria. The data was analyzed by RevMan 5.3. Totally 23 RCTs involving 1 901 patients were included,including 952 in the experimental group and 949 in the control group. The Meta-analysis demonstrated that in terms of the disappearance time of fever,the group of Tanreqing Injection combined with the conventional therapy was superior to conventional therapy group( RR =-1. 03,95%CI[-1. 45,-0. 62],P&lt;0. 000 01); compared with the conventional therapy group,the group of Tanreqing Injection combined with conventional therapy had a higher cure rate for AECB( RR = 1. 17,95% CI[1. 13,1. 23],P &lt; 0. 000 01). The group of Tanreqing Injection combined with levofloxacin had a higher cure rate for AECB than the levofloxacin group( RR = 1. 23,95% CI[1. 08,1. 41],P = 0. 002). The group of Tanreqing Injection combined with cefuroxime had a higher cure rate for AECB than the cefuroxime group( RR = 1. 22,95%CI[1. 05,1. 42],P = 0. 01).The group of Tanreqing Injection combined with cefoperazone sodium and sulbactam sodium had a higher cure rate for AECB than the group of cefoperazone sodium and sulbactam sodium( RR = 1. 22,95% CI[1. 04,1. 44],P = 0. 02). The outcomes of disappearance time of cough and expectoration had a huge heterogeneity,so were used for descriptive analysis. The adverse reactions mainly included skin rash,dizziness,gastrointestinal reactions. Based on the available data and the results of the analysis,the group of Tanreqing Injection combined with Western medicine has a higher cure rate for acute exacerbation of chronic bronchitis,and the effect in reducing symptoms disappearance time. In view of the limited number of included studies,small sample size and low methodological quality,the results of this study need to be confirmed with high-level clinical trials.

Clinical Effect of Qibai Landslide on Jellyfish Injuries in Qinhuangdao City

Objective: To investigate the clinical effects of phlegm and phlegm and magnesium sulfate combined with magnesium sulfate in sea lice in Qinhuangdao City. Methods: A total of 78 patients with sea lice in Qinhuangdao City from June to&#x0D; May 2018 were enrolled. They were randomly divided into control group (n=39 cases) and observation group (n=39 cases). The control group was treated with magnesium sulfate. The observation group was treated with Qibai Colshi Decoction on the basisof the control group. The effect of the patients was evaluated after 5 days of treatment. The disappearance time of symptoms, inflammatory factors and adverse drug reactions were compared. Results: After treatment, the onset, pain time, skin loss, swelling time and course of treatment were shorter in the observation group than in the control group (P&lt;0.05). The levels of inflammatory factors were lower than those before treatment (P&lt;5). The levels of TNF-a, IL-6, HIS and 5-HT in the observation group were lower than those in the control group (P&lt;0.05). The rash, itching, drug allergy, liver and kidney were observed in the observation group and the control group. There was no significant difference in the incidence of dysfunction and blood pressure (P&gt;0.05). Conclusion: The combination of magnesium sulfate and magnesium sulfate in the treatment of sea lice in Qinhuangdao City can shorten the disappearance of symptoms, reduce the level of inflammatory factors, and increase the incidence of adverse drug reactions. It is worthy of popularization and application.

Efficacy of ambroxol hydrochloride in the treatment of exacerbation of chronic obstructive pulmonary disease

Objective To observe the efficacy of ambroxol hydrochloride in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD). Methods From January 2015 to December 2017, 84 patients with COPD exacerbation in Zhuji Central Hospital were selected and randomly divided into two groups according to the digital table, with 42 cases in each group.The control group was treated with routine therapy, the observation group was treated with ambroxol hydrochloride on the basis of routine treatment.The course of treatment in both two groups was 14 days.The clinical efficacy, clinical symptom disappearance time, pulmonary function index, inflammation index and adverse reaction were compared between the two groups. Results The total effective rate in the observation group was 95.24%(40/42), which was higher than that in the control group(78.57%, 33/42), and the difference was statistically significant(χ2=5.126, P 0.05). Conclusion Ambroxol hydrochloride can shorten the time of disappearance of clinical symptoms, improve the clinical efficacy and improve the pulmonary function and inflammation related indicators in the exacerbation period of COPD. Key words: Pulmonary disease, chronic obstructive; Respiratory function tests; Forced expiratory volume; Blood gas monitoring, transcutaneous; C-reactive protein; Neutrophil infiltration; Leukocytes; Ambroxol