Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a useful modality when the target is a lymph node located in the mediastinum, perigastric area or perirectum. Although it is difficult to carry out EUS-FNA of the colon using an oblique view linear scope, we report two cases of successful EUS-FNA of the lesions via the proximal sigmoid colon using a recently available new convex type EUS scope. Case 1 was a 77-year-old Japanese woman noted to have multiple lymph node swelling in the para-aortic area and in the pelvis. Case 2 was a 60-year-old Japanese woman noted to have a large mass in the left lower abdomen. In case 1, oral EUS showed no lymph node swelling. In both cases, EUS with forward-viewing radial echoendoscope was carried out via the anus, and multiple lymph-node swelling or a large mass was observed near the proximal sigmoid colon. In the EUS-FNA for these cases, we used a new convex-type EUS scope that has an oblique view, but with a wide-angled optical device giving a view similar to a forward one. EUS-FNA was successfully carried out on the lesions. The pathological specimen revealed diffuse large B-cell lymphoma in case 1 and gastrointestinal stromal tumor (GIST) in case 2.