Accurate forest parameters are crucial for ecological protection, forest resource management and sustainable development. The rapid development of remote sensing can retrieve parameters such as the leaf area index, cluster index, diameter at breast height (DBH) and tree height at different scales (e.g., plots and stands). Although some LiDAR satellites such as GEDI and ICESAT-2 can measure the average tree height in a certain area, there is still a lack of effective means for obtaining individual tree parameters using high-resolution satellite data, especially DBH. The objective of this study is to explore the capability of 2D image-based features (texture and spectrum) in estimating the DBH of individual tree. Firstly, we acquired unmanned aerial vehicle (UAV) LiDAR point cloud data and UAV RGB imagery, from which digital aerial photography (DAP) point cloud data were generated using the structure-from-motion (SfM) method. Next, we performed individual tree segmentation and extracted the individual tree crown boundaries using the DAP and LiDAR point cloud data, respectively. Subsequently, the eight 2D image-based textural and spectral metrics and 3D point-cloud-based metrics (tree height and crown diameters) were extracted from the tree crown boundaries of each tree. Then, the correlation coefficients between each metric and the reference DBH were calculated. Finally, the capabilities of these metrics and different models, including multiple linear regression (MLR), random forest (RF) and support vector machine (SVM), in the DBH estimation were quantitatively evaluated and compared. The results showed that: (1) The 2D image-based textural metrics had the strongest correlation with the DBH. Among them, the highest correlation coefficient of −0.582 was observed between dissimilarity, variance and DBH. When using textural metrics alone, the estimated DBH accuracy was the highest, with a RMSE of only 0.032 and RMSE% of 16.879% using the MLR model; (2) Simply feeding multi-features, such as textural, spectral and structural metrics, into the machine learning models could not have led to optimal results in individual tree DBH estimations; on the contrary, it could even reduce the accuracy. In general, this study indicated that the 2D image-based textural metrics have great potential in individual tree DBH estimations, which could help improve the capability to efficiently and meticulously monitor and manage forests on a large scale.