Surface Area Of Nanoparticles Research Articles

Preparation of amino-functionalized polyethylene-silica composite membrane and FDH immobilization

Enzymatic CO2 conversion represents a highly efficient, energy-conserving, and environmentally sustainable approach to mitigating the increasing pressure caused by huge carbon emissions and generating valuable products. However, several challenges associate with the process including the instability and recovery difficulty of free enzyme, as well as low solubility of CO2 in mild conditions. Immobilizing enzyme on the amino-functionalized supports presents a viable solution to these issues. Considering the wide application of polymer hollow fiber membranes in the field of CO2 gas–liquid membrane contactor and the characteristics of hydrophilic, biocompatible, and high specific surface area of silica nanoparticles, the amino-functionalized polyethylene (PE)-silica (APS) composite membranes were fabricated via different routes. The morphologies, the loading rates of modified SiO2 and reusability of APS membranes were characterized for a crude screening. Following that, seven kinds of APS membranes were used as the carriers of formate dehydrogenase (FDH) that could catalyze the reduction of CO2 to formate, and their immobilization efficiency and catalytic performance were compared. The results show that 1# and 2# membranes based on carboxyl-modified PE with a loading rate of 5.5 %∼5.6 % and the reusability of above 99 % were more ideal carriers than others. The enzyme activity recovery rate of APS-immobilized FDH (FDH-APS) was separately 367 % and 256 %, proving the intensification action of carriers on the enzymatic reaction. After 10 cycles of use, the relative activity of two kinds of FDH-APS was around 70 % and 78 %, much higher than corresponding particles or membrane attached FDH (25.3 % and 20.4 %). After storage at 4 °C for 20 days, the relative activity of FDH-APS was 82.7 % and 81.0 %, while it was only 61.4 % for free enzyme.

Reactive mesoporous organosoluble multifunctional hyperbranched polymer nanoparticles: Synthesis, post-polymerization reactions and clickable layer-by-layer coating

Synthesis of reactive organosoluble porous polymers, which can be useful for covalent layer-by-layer coatings, is synthetically challenging and not well known. In this work, we demonstrated a new approach to synthesize indole-decorated mesoporous hyperbranched polymer nanoparticles, which can be easily post-modified via triazolinedione (TAD)-indole click reaction. Importantly, further crosslinking of the polymer nanoparticles in solution leads to formation of insoluble mesoporous polymers, where porosity and surface area of the hyperbranched polymer nanoparticles further improved by ∼40%. Consequently, the nanoparticles are useful in layer-by-layer porous coatings and post-surface modifications. While studying their water repellent properties it was noted that nanoparticles having higher surface area/porosity results better water repellent surface which can be further enhanced via suitable surface functionalization using different long chain alkyl functionalities.

Oxytetracycline degradation and antidermatophytic activity of novel biosynthesized MoS2 photocatalysts

The presence of environmental contamination poses a significant threat to life on our planet. Oxytetracycline, an antibiotic with a broad spectrum of effectiveness, demonstrates resistance to biodegradation, potentially resulting in an ecological hazard. In this study, we synthesized both pure and biosynthesized Molybdenum Disulfide (MoS2) nanoparticles using extracts from the bark of Ficusreligiosa L (FR) and leaves of ZiziphusjujubeL (ZJ). These nanopartices were characterized by various analytical methods to assess their efficiency in photocatalytic degradation of oxytetracycline (OTC) and their antidermatophytic activity. X-ray diffraction patterns revealed that the prepared MoS2 catalysts typically exhibited hexagonal phase structure with crystalline size of approximately 13, 6, and 4 nm. Both pure and biosynthesized MoS2 nanoparticles displayed a nanoflake-like morphology with a spherical size distribution. BET surface area analyses exhibited an increase in surface area for biosynthesized MoS2 nanoparticles from 79 to 121 m2g−1. Optical absorption revealed a red shift in band gap energy, decreasing from 2.37 to 2.03 eV for biosynthesized MoS2 nanoparticles. The biosynthesized MoS2:FR nanoparticles exhibited remarkable OTC degradation with 99 % achieved within 100 min along with strong antifungal activity (Minimum Inhibitory Concentration - MIC of 12.5 µg/mL, Minimum Fungicidal Concentration - MFC of 25 µg/mL). These biosynthesized MoS2 catalysts are promising for water treatment purposes.

Effect of calcination temperature of titanium dioxide (TiO2) on adsorption performance of doxycycline hydrochloride

In this work, titanium dioxide (TiO2) was synthesized at different calcination temperatures by sol-gel method using butyl titanate as raw material. The effect of calcination temperature on the crystallinity and adsorption properties of TiO2 were investigated at 300 °C, 450 °C and 600 °C, respectively. The characteristics of TiO2 were analysed by X-ray diffraction, field emission scanning electron microscopy, nitrogen adsorption-desorption analyzer and zeta potential tester. The results showed that the crystal type, specific surface area and zeta potential of TiO2 nanoparticles changed with the increase of calcination temperature and the best performance of anatase crystals happened at the calcination temperature of 300 °C (TiO2@300) for doxycycline hydrochloride (DCH) adsorption. The equilibrium adsorption capacities of DCH was 28.97 mg/g with DCH removal rate of 86.92% at 0.03 g TiO2@300 addition in 100 ml 10 mg/L DCH solution. TiO2@300 could be a promising adsorbent.

Adsorption and photodegradation of organic contaminants by silver nanoparticles: isotherms, kinetics, and computational analysis.

In view of the widespread and distribution of several classes and types of organic contaminants, increased efforts are needed to reduce their spread and subsequent environmental contamination. Although several remediation approaches are available, adsorption and photodegradation technologies are presented in this review as one of the best options because of their environmental friendliness, cost-effectiveness, accessibility, less selectivity, and wider scope of applications among others. The bandgap, particle size, surface area, electrical properties, thermal stability, reusability, chemical stability, and other properties of silver nanoparticles (AgNPS) are highlighted to account for their suitability in adsorption and photocatalytic applications, concerning organic contaminants. Literatures have been reviewed on the application of various AgNPS as adsorbent and photocatalyst in the remediation of several classes of organic contaminants. Theories of adsorption have also been outlined while photocatalysis is seen to have adsorption as the initial mechanism. Challenges facing the application of silver nanoparticles have also been highlighted and possible solutions have been presented. However, current information is dominated by applications on dyes and the view of the authors supports the need to strengthen the usefulness of AgNPS in adsorption and photodegradation of more classes of organic contaminants, especially emerging contaminants. We also encourage the simultaneous applications of adsorption and photodegradation to completely convert toxic wastes to harmless forms.

Successful synthesis of LaFeO3 nanoporous powders with high catalytic and photocatalytic performances: Investigation of precursor effect

Porous LaFeO3 powders with high catalytic and photocatalytic activities were successfully synthesized by sol-gel method using nitrate and chloride precursors. The precursor effect on the crystal structure, morphology, specific surface area and optical properties of the prepared powders was fully determined. Thermogravimetric and X-ray diffraction analyzes showed the formation of the orthorhombic perovskite phase (Pnma, #62) at annealing temperature of 800 and 1000 °C for powder prepared by nitride and chloride salts, respectively. The scanning electron microscopy images revealed a significant effect of precursor type on nanoparticles morphology. It was found that powder prepared from chloride salts is more porous than that prepared with nitrate salts. The estimated surface area of LaFeO3 nanoparticles ranges between 5.94 and 11.56 m2/g and the band gap varies from 2.19 to 2.27 eV. Methylene blue (MB) dye was used to investigate the catalytic and photocatalytic properties of LaFeO3 powders. Both prepared powder types showed good catalytic activity and high photocatalytic performance under visible irradiation in removing MB dye. The adsorption kinetics data of MB molecules on LaFeO3 nanoparticles are well fitted to the pseudo-first order model. Powder synthesized with chloride salts demonstrated high photodegradation efficiency of MB dye compared to that prepared by nitrate salts, which can be attributed to its relatively small band gap and high porosity. These two factors ensure a greater number of photogenerated electrons and more sites for photocatalytic reactions.

Observing zinc oxide nanoparticles suspension stability in various media by using single particle inductively coupled plasma mass spectrometry (SP-ICP-MS)

Zinc oxide (ZnO) nanoparticles are widely used in industry due to their ability to absorb UV light and antibacterial property. The total surface area of ZnO nanoparticles affects its properties and applications. Therefore, the size and stability control of ZnO nanoparticles is very important. We explored the ability of single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) in combination with settling process to analyze ZnO nanoparticles suspended in various media, by which the method allows to detect specific nanoparticles at very low concentration. The settling experiment of ZnO nanoparticles suspended in various media, including deionized water, non-ionic, cationic and anionic surfactants, was carried out to study size, stability and dispersion. The SP-ICP-MS along with settling experiment was set up by suspending different sizes of ZnO nanoparticles in deionized water, Triton X-100, cetyltrimethylammonium bromide and sodium dodecyl sulfate, followed by collecting the sample at various times and vertical distances. Then, the collected samples were diluted and analyzed by SP-ICP-MS to obtain the information on particle size distribution and the particle number concentration. The size and morphology of the ZnO nanoparticles were observed by transmission electron microscopy technique and zeta potential values of particles suspension were measured. The total concentrations of Zn in the suspension were also analyzed by conventional mode ICP-MS to compare with single particle mode ICP-MS. The information obtained in this work allows us to assess the stability of ZnO nanoparticles in various media and shows that the newly developed approach based on SP-ICP-MS with settling experiment can be used as an alternative characterization tool to evaluate the stability of nanoparticles.

Hybridization of cellulose nanocrystals modified ZnO nanoparticles with bio-based hyperbranched waterborne polyurethane sizing agent for superior UV resistance and interfacial properties of CF/PA6 composites

The interface of carbon fiber (CF) reinforced composites has been a long challenging issue that restricts the full utilization of its excellent properties in industrial applications. In present work, a green solvent γ-valerolactone and biogenetic derived gallic acid and tartaric acid were used to prepare a hyperbranched waterborne polyurethane (HWPU) sizing agent. Meanwhile, cellulose nanocrystal modified zinc oxide (CNC–ZnO) nanohybrids were successfully synthesized using a facile one-pot method to improve the dispersibility and specific surface area of ZnO nanoparticles. The hybridization of CNC–ZnO substantially enhanced the thermostability and UV resistance of bio-based HWPU. The mechanical properties of the modified composites were thoroughly examined, revealing remarkable enhancements in flexural strength and interlaminar shear strength, with improvements of 46.5 % and 48.1 % compared to pristine CF. Additionally, the interfacial shear strength test demonstrated a significant increase of 63.6 %. Remarkably, the modified carbon fiber composites retained more than 97 % of their mechanical properties after being subjected to continuous xenon irradiation for a week, highlighting the exceptional ultroviolet resistance derived from the hybrid HWPU sizing agent.

In situ synthesis and stabilization of PVP-coated aluminum nanoparticles by one-step pulsed laser ablation in liquid: Investigation and quantification of PVP coverage effects

This study explored the use of one-step pulsed laser ablation (PLA) in liquid process for in situ synthesis of polyvinylpyrrolidone (PVP) coated highly-stabilized Al nanoparticles (NPs). The effect of different process variables such as laser energy, PVP concentration, and PVP chain length on the composition, size, distribution, and stability of the synthesized NPs was investigated. The results showed that adding PVP to the solution led to smaller average size of NPs with a more uniform distribution, and enhanced resistance to aggregation. This study also revealed that while PVP only partially inhibited the reaction between Al NPs and oxygen during NP generation, it could provide excellent blocking performance against hydroxylation to NPs in subsequent aging experiments. The concept of polymer coverage was introduced to quantify the protective effect of PVP polymers on Al NPs. At 0.1 J laser energy and a K-30 PVP concentration of 10 g/L, a polymer coverage value of 6773 was achieved, maximizing the amount of polymer per unit NP surface area. It was verified that Al NPs' reactivity was most efficiently suppressed under this condition. However, it was observed that the critical polymer coverage value required to suppress the reaction of Al NPs with their surroundings depended on process variables such as laser energy and polymer chain length. This study also confirmed that using high molecular weight polymers can further improve the anti-agglomeration performance and ablation efficiency while lowering the required critical polymer coverage value.

Validating Electrochemical Active Surface Area Determination of Nanostructured Electrodes: Surface Oxide Reduction on AuPd Nanoparticles

Accurate normalization of electrochemical active surface area (ECSA) of nanostructured catalysts and nanoparticles is of utmost importance for catalyst activity determination and comparability. AuxPdy nanoparticles are a highly interesting example, as electrocatalysts for selective oxygen reduction reaction and alcohol oxidation. Most techniques used today for ECSA determination lack accurate validation for nanostructured electrodes and instead rely on reference values determined for macroelectrodes. This includes ECSA determination for AuxPdy nanoparticles, most commonly done by potentiodynamic surface oxide reduction. Here we suggest a versatile approach to validate different ECSA determination techniques for nanoparticle-modified or nanostructured electrodes, using surface oxide reduction of AuxPdy as an illustrative example. Combining this with volume determination by anodic stripping, we electrochemically estimate the NP diameter, which serves as an indication of the accuracy of the obtained ECSA values. Showcasing this for different nanoparticle compositions, we provide experimental conditions for determining AuxPdy nanoparticle ECSA using surface oxide reduction and compare those to parameters reported for macroelectrodes. The approach we introduce herein can be readily applied to a number of different alloy systems, thus, providing a widely applicable approach to determine electrochemical surface areas and validate the transferability of existing macroelectrode characterization techniques to nanostructured or nanoparticle-modified electrodes.

On the structural and optical characterization of zinc aluminate nanoparticles synthesized via green microwave route

Zinc aluminate, a widely employed wide bandgap semiconductor, boasts exceptional mechanical and thermal properties, coupled with a high quantum yield. Its versatile applications include photocatalytic pollutant degradation, utilization in displays, and contributions to the medicinal field. However, challenges arise during synthesis processes, where high-temperature annealing reduces nanoparticle surface area, and cation contamination from precursors impacts material purity. In response to these challenges, green synthesis methods incorporating plant extracts as reductants have emerged to yield higher-quality phosphors. In this study, the focus is on microwave synthesis of Zinc Aluminate using Zinc Nitrate and Aluminum Nitrate in varying ratios as precursors. Comprehensive structural and optical characterizations, including X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Diffuse Reflectance Spectroscopy (DRS), and Photoluminescence Spectroscopy (PL), have been conducted to assess the influence of precursor molar ratios on the spinel growth and optimization of the synthesis process.

Synthesis of N-doped TiO2 nanoparticles with enhanced photocatalytic activity for 2,4-dichlorophenol degradation and H2 production

Nitrogen-doped titanium dioxide (N-TiO2) nanoparticles were prepared using a modified sol-gel method. The as-prepared nanoparticles were characterized by state-of-the-art techniques for their optical, structural and morphological properties. The crystallite size, surface area and bandgap energy of reference TiO2 and N-TiO2 nanoparticles were found to be 16.1 and 10.9 nm, 83.6 and 131.8 m2 g−1 and 3.23 and 2.89 eV, respectively. The photocatalytic activities, in terms of 2,4-dichlorophenol (2,4-DCP) degradation, of reference TiO2 and N-TiO2 were found to be 46.9% and 65.4% at 120 min of treatments under UV light irradiation and 21.5% and 77.6% at 240 min of treatment under visible light irradiation, employing 153.4 µM 2,4-DCP, 1 g/L photocatalyst dosage, and pH 5.6. Interestingly, considerable H2 production rate (i.e., 386 μmol h−1 g−1) was observed for visible/N-TiO2 system in presence of 0.2 wt% Pt. The study revealed that visible/N-TiO2 photocatalytic system can be used as an economically viable technology for environmental sustainability.

Alcohol production from fatty acids via Ni3Fe/Rutile: Revealing the role of oxygen vacancy and metal-support electronic density characteristics

Ni3Fe clusters anchored on rutile (R-TiO2) were synthesized by hydrothermal (HT), coprecipitation (CP) and impregnation (IM) methods, and the catalytic performance of different NiFe/R-TiO2 catalysts were investigated for hydrogenation of fatty acid into alcohol. Notably, HT-NiFe/R-TiO2 catalyst, with the highest specific surface area and Ni3Fe nanoparticles dispersion, exhibited the best hydrogenation activity towards alcohol production, with complete conversion and yield reach of 92.5 % at 4 MPa H2, 210 ℃ and 6 h. The structure–reactivity relationship was investigated by a series of catalysts characterization, DFT calculation and corroborated through hydrogenation performance evaluations. Anchoring Ni3Fe clusters onto highly dispersed basic site surfaces with different Ov concentrations can change the electron distribution and strength of the metal-support interaction, causing more stable adsorption of the H and acids molecular toward fatty alcohol production. This work provides further insight into the structure–activity of NiFe/TiO2 catalysts synthesized through different methods.

Influence of Nanoparticle Size Distributions on the (in)Stability and Rheology of Colloidal SiO2 Dispersions and HPAM/SiO2 Nanofluid Hybrids

This study investigated the relationship between variations in the size distribution and the specific surface area of SiO2 nanoparticles and the in(stability) and rheology of their colloidal dispersions and their resulting silica-poly(acrylamide) hybrids. Thus, SiO2 nanoparticles with size distribution in the range 40-173 nm, corresponding to 70-26 m2/g of specific surface area, were used in the studies. The results show a correlation between the average particle size distribution/the specific surface area of silica nanoparticles with the in(stability) and the rheology of their dispersions, such that an increase in the particle size distribution from 40 to 173 nm corresponds to a decrease in dispersion instability index from 0.913 to 0.112. However, in the silica-poly(acrylamide) hybrids, a change in the particle size distribution from 40 to 173 nm corresponds to an increase in the nanofluid instability index from 0.1913 to 0.929. In the hybrid materials, interactions between polymer chains and nanoparticles lead to size-induced stability and rheological behaviour, such that the broadening of the FTIR peak around 1,000 cm-1 in the nanohybrids was related to an Si-O-H bending vibration that arose because of dominating hydrogen bonding arising from the interaction of the hydroxyl groups and the amide groups in the polymer. The rheological characteristics of the hybrid nanofluids show that the relative viscosity and shear sensitivity of the colloidal dispersions or their hybrids can be tailored by the average particle size distribution of the nanoparticles.

Electrochemical sensor based on polyaniline supported CdS/CeO2/Ag3PO4 nanocomposite for Malathion detection

Different nanomaterials in single (CeO2), binary (CdS/CeO2 and Ag3PO4/CeO2), ternary CdS/CeO2/Ag3PO4 (4:1 molar ratio) and conductive polymer supported (PANI-CdS/CeO2/Ag3PO4) were synthesized by co-precipitation method. Elemental analysis, crystal structure, surface area, morphology and optical properties of the as-synthesized nanoparticles were characterized. Electrochemical behavior of glassy carbon electrode modified by polyaniline supported CdS/CeO2/Ag3PO4 nanocomposite were also characterized by electrochemical impedance spectroscopy and cyclic voltammetry in 0.1 M of K3[Fe(CN)6] containing 0.1 M KCl at pH 7 with a frequency range of 0.1 to 1000 Hz, with an amplitude of 50 mV. The voltammogramm shows that the process of all as synthesized nanocomposites modified glassy carbon electrode is diffusion controlled. Under optimum conditions, the electrochemical sensor showed Malathion concentrations in linear range of 1-13 × 10−7 M, good reproducibility, and no interference by other pesticides and high recovery values around 98.90%. As-synthesized nanocomposite modified glassy carbon electrode exhibits the lowest detection limit of 3.0 × 10−9 M for Malathion detection. The simplicity of preparation, high sensitivity, good stability and reproducibility of this nanostructured polyaniline supported CdS/CeO2/Ag3PO4 electrode can be a potential candidate for application in the detection of Malathion.

Averaging Strategy for Interpretable Machine Learning on Small Datasets to Understand Element Uptake after Seed Nanotreatment.

Understanding plant uptake and translocation of nanomaterials is crucial for ensuring the successful and sustainable applications of seed nanotreatment. Here, we collect a dataset with 280 instances from experiments for predicting the relative metal/metalloid concentration (RMC) in maize seedlings after seed priming by various metal and metalloid oxide nanoparticles. To obtain unbiased predictions and explanations on small datasets, we present an averaging strategy and add a dimension for interpretable machine learning. The findings in post-hoc interpretations of sophisticated LightGBM models demonstrate that solubility is highly correlated with model performance. Surface area, concentration, zeta potential, and hydrodynamic diameter of nanoparticles and seedling part and relative weight of plants are dominant factors affecting RMC, and their effects and interactions are explained. Furthermore, self-interpretable models using the RuleFit algorithm are established to successfully predict RMC only based on six important features identified by post-hoc explanations. We then develop a visualization tool called RuleGrid to depict feature effects and interactions in numerous generated rules. Consistent parameter-RMC relationships are obtained by different methods. This study offers a promising interpretable data-driven approach to expand the knowledge of nanoparticle fate in plants and may profoundly contribute to the safety-by-design of nanomaterials in agricultural and environmental applications.

Reuse of Lignin to Synthesize High Surface Area Carbon Nanoparticles for Supercapacitors Using a Continuous and Single-Step Aerosol Method.

There is a growing demand for the synthesis of high surface area carbons, also known as carbon nanoparticles (CNPs). Existing synthesis methods for high surface area carbons have limited environmental benignity and economic viability due to the requirement of multistep and batch processes and harsh activating and/or templating chemicals. Herein, we demonstrate the synthesis of high surface area CNPs from lignin, a waste byproduct, through a single-step, continuous gas phase aerosol technique without the use of activating or templating chemicals. This continuous approach requires significantly less time for synthesis: on the order of seconds in comparison to hours for conventional methods. Properties of carbon materials synthesized from lignin are controlled by temperature and residence time, and the role of these parameters inside the aerosol reactor on carbon nanoparticle size, morphology, molecular structure, and surface area is systematically investigated. Furthermore, the as-obtained carbon nanoparticles are tested for specific capacitance, and the best-performing material (surface area 925 m2/g) exhibited a specific capacitance of 247 F/g at 0.5 A/g with excellent capacity retainment of over 98% after 10,000 cycles. This is a clear demonstration of their superior performance compared with supercapacitors synthesized earlier from lignin. Overall, the simple (single-step, continuous, and rapid) operation and the avoidance of the use of activating/templating chemicals make the aerosol technique a promising candidate for the scalable and sustainable synthesis of CNPs from lignin.

VAMAS TWA2 interlaboratory comparison: Surface analysis of TiO2 nanoparticles using ToF-SIMS

Due to the extremely high specific surface area of nanoparticles and corresponding potential for adsorption, the results of surface analysis can be highly dependent on the history of the particles, particularly regarding sample preparation and storage. The sample preparation method has, therefore, the potential to have a significant influence on the results. This report describes an interlaboratory comparison (ILC) with the aim of assessing which sample preparation methods for ToF-SIMS analysis of nanoparticles provided the most intra- and interlaboratory consistency and the least amount of sample contamination. The BAM reference material BAM-P110 (TiO2 nanoparticles with a mean Feret diameter of 19 nm) was used as a sample representing typical nanoparticles. A total of 11 participants returned ToF-SIMS data, in positive and (optionally) negative polarity, using sample preparation methods of “stick-and-go” as well as optionally “drop-dry” and “spin-coat.” The results showed that the largest sources of variation within the entire data set were caused by adventitious hydrocarbon contamination or insufficient sample coverage, with the spin-coating protocol applied in this ILC showing a tendency toward insufficient sample coverage; the sample preparation method or the participant had a lesser influence on results.

Magnetic Solid Phase Extraction for Determination of Dyes in Food and Water Samples

Recently, magnetic solid-phase extraction (MSPE) is an important technology due to its use in analytical chemistry, biotechnology, and medicinal fields. MSPE shows rapid isolation of target analyte from large volume samples, the huge surface area of magnetic nanoparticles (MNPs), and simplicity in application due to using an external magnetic field instead of using packing column, centrifuge and filter papers. The aim of this review is to evaluate the extraction and determination of dyes in food and water samples by using the MSPE technique.

Hydrogel-Based Electrodeposition of Copper Nanoparticles for Selective Detection for Hydrogen Peroxide

A copper-modified indium tin oxide (ITO) electrode was utilized as an electrocatalytic sensing platform for hydrogen peroxide (H2O2) detection. In this study, instead of conventional solution-phase electrodeposition, electrochemical deposition was used to deposit Cu on an ITO electrode with agarose hydrogel. The hydrogel-based Cu nanoparticles exhibited a more evenly dispersed distribution compared to those in the solution phase. Additionally, by incorporating agarose hydrogel as a solid electrolyte, the overall active surface area of Cu nanoparticles on the electrode surface was increased, mainly resulting from a decrease in the aggregation of Cu nanoparticles. Cyclic voltammetry and chronoamperometry confirmed that the resulting Cu nanoparticles possessed distinct electrocatalytic activity for H2O2 reduction and good selectivity for various interfering substances. The chronocoulometry response of the fabricated sensor obtained at −0.6 V (vs. Ag/AgCl) increased linearly with a dynamic range of 1–500 μM, and the limit of detection for H2O2 was 1.73 μM. Our research provides new possibilities for the electrochemical synthesis of metal nanoparticles for non-enzymatic sensing applications.