The objective of this study is to examine the impact of self-efficacy, motivation, and entrepreneurship education on the level of interest in entrepreneurship among teens from PIK-R in Tipes Village, Serengan, Surakarta Central Java, Indonesia. This study used a purposive sampling technique, selecting a sample of 41 youths from the overall population. The material used in this study included interviews, questionnaires, and documentation. The study employs interest in entrepreneurship as the dependent variable, while selfefficacy, motivation, and entrepreneurship education are used as the independent factors. The methodologyused in this study is multiple linear regression. The findings of the study indicate that self-efficacy was found to have an insignificant impact on entrepreneurial interest. However, both motivation and entrepreneurship education were found to have significant impacts on entrepreneurial interest among these teenagers. In summary, there is a partial correlation between motivational self-efficacy and entrepreneurship education, and the level of interest in entrepreneurship among teens from PIK-R in Types Village, Serengan, Surakarta, Central Java, Indonesia.