In this study, the two-dimensional numerical simulations are conducted to study the flow field characteristics, turbine performance and loss mechanism of integrated system of rotating detonation combustor and supersonic turbine under two different directions of detonation wave propagation. The results indicate that the propagation direction of RDW affects the incident angle between OSW and guide vanes, resulting in different operating modes for aligned and unaligned modes. OSW in the turbine cascade undergoes the leading-edge shock, blade surface reflection and trailing edge diffraction. The backward-propagating rake-type shock envelope is formed due to leading-edge shock of the rotor. In misaligned mode, the stator has higher damping of both pressure and temperature. The stator significantly improves the circumferential uniformity of both velocity and pressure, particularly when operating in aligned mode. The total pressure loss in aligned mode is less, therefore the turbine achieves higher rim work and efficiency. The viscosity is one of the main sources of loss in the flow field. The reflected shock waves at the leading edge of the rotor and in the stator cascade are the primary factors contributing to the leading-edge vortices on the stator vanes.