This study investigates the resilience of dual-system reinforced concrete (RC) structures impacted by progressive collapse where the local failure of a primary structural component leads to the sequential collapse of adjoining elements. The study is conducted on buildings designed in the United Arab Emirates in the context of extreme events. Nonlinear dynamic analysis of twenty-seven different building models is performed to evaluate the impact of critical variables, building height, and column spacing on progressive collapse potential under the Unified Facilities Criteria (UFC) regulations. The research methodology aims to study impacts associated with sudden removal of critical columns (corner, edge, and internal) that replicate severe accident scenarios in buildings. The structural responses were assessed based on the ASCE 41 performance design criteria. The formation of plastic hinges was analyzed to determine the ductility and resilience of the structures. The study finds that buildings with removed corner columns exhibit more significant vertical displacements than those with edge or internal column removals. The results also indicate that columns adjacent to the removed ones generally remained elastic and within their structural capacities, showing structural resilience to localized damage. However, the flexural strength of RC flat slabs near removed or adjacent columns demonstrates insufficient flexural capacities. This study underscores the imperative for enhanced design strategies and emphasizes the critical importance of bolstering structural resilience against extreme events. Moreover, it intends to draw the attention of policymakers locally to the need to consider progressive collapse when designing reinforced concrete structures.