The article is devoted to the study of the economic significance of the subsistence minimum on the activities of small business entities. The dynamics of the living wage for able-bodied persons for the years 2018–2022 have been analyzed. The approved level of the subsistence minimum for 2023 in accordance with the Law of Ukraine "On the State Budget for 2023" was considered. The size and value of indicators in the activities of small business entities, which are tied to the subsistence minimum in 2023, were analyzed. The single tax rates, annual income limits and the size of the single social contribution for individual entrepreneurs in 2023 were studied. It was found that the subsistence minimum is defined as the value of a set of food products sufficient to ensure the normal functioning of the human body and preserve its health, as well as a minimum set of non-food goods and a minimum set of services necessary to satisfy the basic social and cultural needs of an individual. In general, it was discovered that the indicator of the level of subsistence minimum has a significant impact on the economic activity of a small business, as it is used in the calculations of the minimum wage, the amount of the single tax rate (ten percent of the subsistence minimum for an able-bodied person) , the amount of tax social benefits (this value is used in the calculation of personal income tax), the amount of alimony and calculation of wages: salary minimum (the official salary must be at least the subsistence minimum for an able-bodied person) and salary indexation (wages are indexed within the subsistence minimum for an able-bodied person) . The tax burden on the first group of individual entrepreneurs is also increasing, which makes it necessary for these business entities to take into account the established annual income limits for 2023 in order to prevent the transition to another group of the single tax or to the general taxation system. The adopted Law of Ukraine "On the State Budget for 2023" provides for an increase in the subsistence minimum, which requires further analysis of the impact and calculation of tax rates for small business entities.