Tophaceous gout of the symphysis pubis is an exceedingly rare event, with only four other cases reported in the literature [1–4]. Gout is the oldest recognized arthropathy and results from the deposition of monosodium urate crystals [5]. Gouty tophi are a consequence of prolonged hyperuricemia and can be found in soft tissues, tendon sheaths, joints, and bony prominences [3]. Calcium may precipitate with the urate crystals to varying degrees, making tophi more apparent on radiographs. Gout most often afflicts the feet, ankles, knees, hands, and elbows, in decreasing order of frequency [5]. This case is exceptional because it demonstrates the hallmark imaging characteristics of tophaceous gout in spite of its uncharacteristic location. The symphyseal joint space is preserved. The erosions on either side of the joint are well-demarcated with sclerotic margins. These erosions have been described as “punched-out,” resembling “mousebites,” with overhanging edges that are typical of gout. The association of these erosions with the hyperdense calcified tophus is a reflection of the indolence of this arthropathy [5]. This case diagnosis may be achieved from the images and information provided. Following the patient’s initial presentation, a skeletal survey and laboratory workup were performed. The serum uric acid level was elevated, in keeping with the suspected diagnosis. Skeletal survey was notable in that the first tarsometatarsal (TMT) joint was unaffected. However, other sites, including the ulnar styloid process, displayed erosions with sclerotic margins and overhanging edges (Fig. 1). The combination of imaging findings, history and laboratory evaluation led to this patient’s diagnosis of tophaceous gout involving the symphysis pubis. Synovial fluid analysis of this joint was deferred. Other conditions that may afflict the symphysis pubis include metastasis, plasmacytoma, primary osseous neoplasm such as chondrosarcoma, septic arthritis, osteoarthritis in isolation or in association with calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, and amyloidosis. Neoplasms, both primary and secondary, and infection are much less likely given the well-defined pattern of osteolysis with sclerotic margins. Preservation of the joint space and lack of periosteal elevation further mitigate against these diagnoses on imaging alone. Septic joint is unlikely in an afebrile patient with normal white blood cell count. This patient had no systemic symptoms such as weight loss and generalized malaise to suspect malignancy. Erosions are typical of osteoarthritis involving the symphysis pubis, as in the temporomandibular, acromioThe case presentation can be found at doi:10.1007/s00256-010-0898-0