Student Research Committee Research Articles

The effects of melatonin supplementation on neurobehavioral outcomes and clinical severity in rodent models of multiple sclerosis; a systematic review and meta-analysis.

Through the antioxidant and anti-inflammation pathways, melatonin is proposed as a safe and effective intervention in neurological diseases. This study aims to evaluate the effects of melatonin supplementation on the neurobehavioral and clinical outcomes in animal models of multiple sclerosis (MS). This study was conducted following the PRISMA statement. Animal studies that reported the effects of melatonin in preclinical MS models, including the experimental autoimmune encephalomyelitis (EAE) and cuprizone model for demyelination are included in this study. A systematic search in PubMed, Web of Science, Embase, and Scopus up was conducted in April 2023. The collaborative Approach to Meta-Analysis and Review of Animal Experimental Studies (CAMARADES) critical appraisal tool was used for the quality assessment of the studies and the quantitative synthetizes were conducted using the comprehensive meta-analysis software. Out of 542 studies, finally 21 studies, including 14 studies in the EAE model and 7 studies of the toxic demyelination method with cuprizone were included. The route of administration was intraperitoneal in 18 studies, oral in 2 studies, and subcutaneous in 1 study. The quantitative synthesis of the EAE clinical severity scale was associated with significant differences (standardized mean difference [SDM]: - 2.52; - 3.61 to - 1.42; p value < 0.01). In subgroup analyses, the difference was statistically significant in the mouse subgroup (SMD: - 2.60; - 3.74 to - 1.46; p value < 0.01). This study encountered that melatonin may be associated with improved behavioral and cognitive outcomes of preclinical models of MS with acceptable safety profiles. The research was supported by the Student Research Committee, Tabriz University of Medical Sciences (grant number: 71005).

Effects of the Blended Workshop Learning and Web-Based Learning Sequence on the Learning Level: A New Experiment

Background: Background: The blended electronic learning system, raised as a new approach in educational planning with great enthusiasm, seeks novel ways to properly combine the media; however, the sequence of in-person and distance educational methods is an issue neglected so far. This study aims to compare the effect of the sequence of blended workshop learning and web-based learning on the learning level of biostatistics in students who were members of the Student Research Committee at Arak University of Medical Sciences.&#x0D; Methods: This is a quasi-experimental study with an alternative treatment design. The statistical population consisted of the students who were members of the Student Research Committee of the university, including 38 medical students and 15 health students, who were selected through census sampling due to their limited number. The data were selected with 2 questionnaires: demographic characteristics and biostatistics multiple-choice questions to assess learning of statistical concepts in three levels of literacy, reasoning, and thinking. The validity and reliability of the translated statistics questions were assessed through content validity and bisection, respectively. The data were analyzed in SPSS-16 through independent and paired t-tests and analysis of variance.&#x0D; Results: The results showed a statistical difference between the groups in both faculties in statistical literacy and reasoning in blended learning (p&gt;0.05). However, regarding statistical thinking, the difference was significant in the health faculty (p=0.044) and insignificant in the medical school (p&gt;0.05).&#x0D; Conclusion: Given the statistical difference observed in the health group, we suggest holding in-person courses at first and online courses then.

Cardiac hydatid disease; a systematic review

Background and objectivesHuman cystic echinococcosis (CE), is a common health problem in low- and middle-income countries. Cardiac involvement is a relatively rare manifestation of Echinococcus infection. This study aims to summarize the evidence regarding the features of cardiac CE.MethodsCase series of the patients with cardiac CE, were included in this study. Non-English papers, case reports, reviews, letters, , commentaries, and conference abstracts were not included. A systematic search was conducted in PubMed and EMBASE databases and the risk of bias in the included studies was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist.ResultsOut of 3985 results of the searches, finally 37 studies were included in this systematic review. Based on available evidence, cardiac involvement is an uncommon but serious presentation of CE which presents with some non-specific signs and symptoms. Dyspnea, chest pain, and palpitation are the most common symptoms of the disease and normal sinus rhythm is the most common Electrocardiogram (ECG) feature. The disease is not associated with high mortality in case of timely diagnosis and appropriate management.DiscussionConsecutive and complete inclusion of participants, statistical analysis, and appropriate reporting of the demographics were the sources of bias in the included studies. The exclusion of non-English papers was a limitation during the review process.FundingThe research protocol was approved and supported by the Student Research Committee, Tabriz University of Medical Sciences (grant number: 69380).RegistrationThis study was registered in the International prospective register of systematic reviews (PROSPERO ID: CRD42022381204).

The Study of the Relationship between Managers Communication Skills and Organizational Performance among Nurses in Educational Hospitals

The Study of the Relationship between Managers Communication Skills and Organizational Performance among Nurses in Educational Hospitals

Interleukin-29 profiles in COVID-19 patients: Survival is associated with IL-29 levels.

Interleukin-29 profiles in COVID-19 patients: Survival is associated with IL-29 levels.

Correlation between Creativity and Entrepreneurial Skills in Managers of Educational Hospitals

Correlation between Creativity and Entrepreneurial Skills in Managers of Educational Hospitals

The Quality of Life of Women with Addicted Husbands and its Related Factors in Gorgan, Iran

1- Student Research Committee, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran 2- Faculty of Nursing & Midwifery, Nursing Research Center, Golestan University of Medical Sciences, Gorgan, Iran 3- Nursing and Midwifery Care Research Center, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran 4- Development Research Center, Department of Biostatistics and Epidemiology, Faculty of Health, Golestan University of Medical Sciences, Gorgan, Iran 5- Psychiatric and Mental health Nursing Department, Nursing and Midwifery Care Research Center, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran , maghsoudi@nm.mui.ac.ir

The Epidemiology of Various Behavioral Disorders in Children and Adolescents of the World: A Comprehensive Systematic Review and Meta-Analysis

Background: The behavioral disorders in children and adolescents include a group of behaviors by which the children and adolescents suffering from them repeatedly violate the basic rights of others or violate social norms. Due to the importance of these disorders and the lack of comprehensive statistics about it throughout the world, the present study aimed to determine the uniformity of statistics of various behavioral disorders in children and adolescents in the world through a comprehensive systematic review and meta-analysis. Methods: In this systematic review and meta-analysis study, the collected data of the studies were systematically extracted based on the prevalence of behavioral disorders in children and adolescents throughout the world according to the PRISMA guidelines from Persian databases of SID, MagIran, IranMedex, and IranDoc and international databases of ProQuest, ScienceDirect, Scopus, Medline (PubMed), Web of Science (WoS) and Google Scholar search engine through using the keywords of Behavioral Disorders, Attention Deficit Hyperactivity Disorder, Anxiety Disorder, Aggression, Nail-biting, Thumb sucking, Mood Disorder, Tics, Children and Prevalence, and their equivalents from MeSH browser without any time limit until 2020. To analyze the eligible studies, the random-effects model was used, and the heterogeneity of the studies was investigated with the I2 index. The data were analyzed using the Comprehensive Meta-Analysis software (Version 2). Results: Out of 9869 studies, 257 studies met the inclusion criteria. In a review of 67 studies with a sample size of 191355, the prevalence of total behavioral disorders in children and adolescents worldwide was 17.8% (95% CI: 14.4-2.8%), which regarding the subgroup analysis by different continents, the highest prevalence of total behavioral disorders was obtained from Asia 21.3% (95% CI: 17.25-3.9%). Also, regarding the subgroup analysis based on the types of behavioral disorders, the highest prevalence of behavioral disorders in children and adolescents in the world was related to the Thumb sucking index 21.2% (95% CI: 11.1-1.36.7%). The highest prevalence of Thumb sucking was 37.2% (95% CI: 11.6-72-8.8%) in America. Conclusion: The results of this study revealed that the prevalence of various behavioral disorders, especially Thumb sucking and Aggression, is high in children and adolescents worldwide. Therefore, it shows the importance of accurate diagnosis with extensive screening programs and appropriate planning for prevention. Funding Statement: Student Research Committee of Kermanshah University of Medical Sciences, Deputy for Research and Technology, Kermanshah University of Medical Sciences (IR) (3010805). Declaration of Interests: The authors declare that they have no conflict of interest. Ethics Approval Statement: Ethics approval was received from the ethics committee of deputy of research and technology, Kermanshah University of Medical Sciences (3010805).

The Effect of Group Hope Therapy on Spiritual Health of Cancer Patients: A Semi Experimental Study

Background and Objectives: Cancer is one of the most common chronic diseases that affects the spiritual health of patients. Therefore, interventions are needed to improve the spiritual health of patients. Therefore, the purpose of this study was to determine the effect of group hope therapy on the spiritual health of cancer patients. Materials and Methods: This quasi-experimental study was performed from December to March 2015 in Gonabad city. The study population was all cancer patients and the research environment was cancer clinic. Forty patients were selected by simple random sampling method and randomly divided into experimental (n=20) and control (n=20) groups. After completing demographic and spiritual health Paloutzian & Ellison questionnaires, Hope group therapy sessions were performed in 8 sessions of 90 minutes once a week in the experimental group; but the control group received only routine care. The spiritual health questionnaire was completed again at the end of the last session. Data were analyzed using independent t-test, paired-t test and covariance analysis. Results: According to the results of the study, the two groups didnchr('39')t have any significantly difference in terms of demographic variables (p>0.05). The mean score of spiritual health after the intervention showed a significant difference between the experimental and control groups (p<0.001). Group hope therapy also improved the spiritual health of cancer patients in the experimental group (p=0.012). Conclusion: Considering the findings of the study, which showed that group hope therapy affects the spiritual health of cancer patients, it is recommended to use this method in the care and treatment of cancer patients. Key words: Group Hope therapy, Spiritual health, Cancer Funding: This research was funded by the Student Research Committee of Gonabad University of Medical Sciences. Conflict of interest: None declared. Ethical approval: The Ethics Committee of Gonabad University of Medical Sciences approved the study (IRGMU.REC.1394.14). How to cite this article: Saberi Noghabi E, Zarvandi R, Jeddi H, Jamali Noghabi Z, Mazloum Shahri S B, Noori R. The Effect of Group Hope Therapy on Spiritual Health of Cancer Patients: A Semi Experimental Study. J Rafsanjan Univ Med Sci 2020; 19 (4): 369-82. Farsi

Zahraei Method for Discovery of New Genes, A Unique Way to Find Ancient Genes and Their Evolution

Shiva Raeisi Dehkordi, Seyed Ali Hossein Zahraei*, Zahra Golafshan, Sepideh Ahmadipour and Melika Rajaei Author Affiliations Student research committee, Shiraz University of medical sciences, Shiraz, Iran Received: May 03, 2020 | Published: May 12, 2020 Corresponding author: Seyed Ali Hossein Zahraei, Student research committee, Shiraz University of medical sciences, Shiraz, Iran DOI: 10.26717/BJSTR.2020.27.004528

Erratum: Correction of the Authors' List and Affiliations.

In the original investigation entitled “Cervical Epidural Steroid Injection: Parasagittal versus Midline Approach in Patients with Unilateral Cervical Radicular Pain; A Randomized Clinical Trial.”[1] which was published in April 2019 issue of the journal, one author name has been unintentionally omitted from the final draft and the affiliations were wrongly assigned. There is an error in the author list of this article, which should be corrected as follows: “Masoud Hashemi,1 Payman Dadkhah,1 Mehrdad Taheri,1 Ebrahim Golmakani,1,2 Kasra Dehghan,1 Rouhollah Valizadeh.3”. The affiliations are also corrected as follow: “1Pain Management Fellowship, Department of Anesthesiology, Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran; 3Department of Epidemiology, Student Research Committee, Iran University of Medical Sciences, Tehran, Iran”. The article was corrected online.

Blood Pressure in Wild‐type and Ts65Dn Mice at 6 Months of Age

Down syndrome (Ds) results from triplication of the 21st chromosome, and is estimated to occur 1 in every 700 births in the United States. Many people with Ds exhibit cardiovascular challenges including pulmonary hypertension and lower resting blood pressure. We tested the hypothesis that Ts65Dn mice, a model of Ds, would exhibit lower blood pressure compared to wild‐type mice. The CODA volume‐pressure tail cuff system by Kent Scientific (Torrington, CT) was used to quantify systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) in 6–month wild‐type (n=9) and Ts65Dn (n=7) male mice. Two trial days were administered for each mouse that included 15 inflation/deflation cycles of the cuff on each day. The trial was considered successful if ≥7 of the 15 cycles were accepted by the software. The mean of the 7–15 cycles was calculated for each mouse (DBP, SBP and MAP separated). If the 2nd trial mean differed by &gt;10 mmHg for SBP the mouse was excluded from the analysis. Data are shown as wild‐type vs. Ts65Dn; MEAN ± SD; * = p&lt;0.05. Ts65Dn mice displayed a reduced SBP (104 ± 9 vs. *96 ± 4 mmHg). DBP (77 ± 9 vs. 69 ± 5 mmHg) and MAP (85 ± 9 vs. 78 ± 4 mmHg) were not different in this early analysis. These data suggest that Ts65Dn mice may be an appropriate model to use in understanding cardiovascular function in Ds. Further investigation is warranted to confirm these findings across the lifespan of wild‐type and Ts65Dn mice.Support or Funding InformationFunded by 1 R15 HD076379‐01A1 (LRD), HKB supported by the Ignite fellowship and Le Moyne College Student Research Committee, CNR supported by 1 R15 HD076379‐01A1S1.This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.

Undergraduate students' attitudes towards research: lessons from an international branch campus in the UAE

The study discusses efforts to inculcate a research culture among undergraduate students at an international branch campus of a British university in the UAE. It presents a case study of the work of a student research committee, and analyses primary qualitative and quantitative data from a sample of undergraduate students. Findings indicate that students regard research as valuable, particularly in relation to their future careers. Nonetheless, perceived challenges associated with research are highlighted. Implications for practice are discussed.

The formation of a medical student research committee and its impact on involvement in departmental research

ABSTRACTOver the past ten years, medical students have increased their research activity to be competitive for orthopaedic residency positions throughout the country. This increase may favor students at institutions with a strong history of research production and well-established research departments with supporting staff. To compete with these institutions, a Musculoskeletal Research Committee was developed at a southern academic institution to provide a mutually beneficial link between orthopaedic research faculty and medical students. This manuscript describes the formation of this committee and the resultant involvement of young medical students in departmental research over a one year period. Composed of students and faculty, the committee developed a Research Guide for Medical Students, Research Database and Student List, Medical Students’ Webpage, and Routing Form, and holds quarterly meetings for those students active in orthopaedic research. With this platform, the committee aimed to increase young student involvement in research and provide a stratified level of study participation among upper-level students for continued mentorship. In one calendar year, the total number of first and second-year students participating in department research increased 460% (5 to 28). Also, the total number of research projects with student involvement from these two classes increased 780% (5 to 44). The introduction of a research committee is an effective method of stimulating student interest in departmental research. Early participation results are promising, and this method may be applicable to other departments and institutions hoping to increase research productivity.Abbreviations: IRB: Institutional Review Board

Research, relevance and respect: Co-creating a guide about involving young people in social research

Although children and young people in schools should be asked for their informed consent to participate in research, they rarely have a say in what research takes place in their school. We draw upon debates about youth participation in research to explore young people's preferences about their involvement in research and how they want to be treated by researchers. To do so, we reflect on the process of co-creating a guide for involving young people in social research with a Student Research Committee and their teacher; this involved group discussions, ranking exercises and other interactive sessions that generated ideas about the preferences of the young people about participating in research. Overall, the involvement of young people in all stages of the research process will enhance what they get out of participating and the extent to which they feel their voices have been heard.

Student Research Committee as a Model for Development of Medical Research Projects.

Student Research Committee (SRC) has been developed a subset of each university's Vice chancellor for research in purpose of research training for motivated students and conducting their research interests. In this paper, we evaluated effect of SRCs on Iran's research through Scopus database and showed that SRCs has a remarkable impact on Iran's publication performance.

Patient Safety Leadership Walkrounds: Promoting a Safety Culture in Developing Countries

*Corresponding Author: Mohammad Saadati, Iranian Center of Excellence in Health Management, School of Health Services Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran. Email: hcm.2020@gmail.com p Patient Safety Leadership Walkrounds: Promoting a Safety Culture in Developing Countries Mohammad Saadati* (PhD Candidate); Mehdi Nouri (MSc); Robert McSherry (PhD) 1. Iranian Center of Excellence in Health Management, Student Research Committee. Department of Health Service Management, School of Health Services Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran. 2. Road Traffic Injury Research CenterShahid Mahallati Hospital, Quality Improvement Office. 3. Professor of Nursing and Practice Development, University of Teesside, Middlesbrough, England, United Kingdom.

An Analysis on Views of Iranian Women about Incentive Policies on Childbearing Decision-making

5 Student Research Committee of Jahrom University of Medical Sciences, Jahrom, Iran Department of Emergency Medicine, Jahrom University of Medical Sciences, Jahrom, Iran Department of Community Health, Jahrom University of Medical Sciences, Jahrom, Iran Department of Gynecology and Obstetrics Jahrom University of Medical Sciences, Jahrom, Iran Department of periodontology, Assistant professor of Shiraz Dental School,Shiraz, Iran.

Helicobacter pylori Antibiotic Resistance: What is the Future of Treatment?

Student Research Committee, Babol University of Medical Sciences, Babol, IR Iran Vice-Chancellery for Health, Babol University of Medical Sciences, Babol, IR Iran Department of Internal Medicine, Rohani Hospital, Babol University of Medical Sciences, Babol, IR Iran Corresponding author: Mohammad Zamani, Student Research Committee, Babol University of Medical Sciences, Babol, IR Iran. Tel: +98-9359493131, E-mail: mzamani20@gmail.com

Combined effects of silver nanoparticles and mercury on gill histopathology of zebrafish (Danio rerio)

Borhan Mansouri, Raouf Rahmani, Nammam Ali Azadi, Seyed Ali Johari Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran Biostatistics Department, Iran University of Medical Sciences, Tehran, Iran Department of Fisheries, Faculty of Natural Resources, University of Kurdistan, Kurdistan, Sanandaj, Iran Journal of Coastal Life Medicine 2016; 4(6): 421-425