Experimental and numerical studies on the performance of light-gauge slotted steel stud walls subjected to fire are presented in this paper. Four full-scale light-gauge slotted steel stud walls were tested under the ISO-834 standard fire loading. Temperatures at the location of exposed surface, unexposed surface, and cross section of steel studs were measured. Spalling of the heated gypsum board during testing was investigated. The major factors affecting the behavior of this type of wall, including the height of the web, layers of gypsum boards and use of mortar on unexposed surface, were studied.Based on the test results, a three-dimensional FE model of the light-gauge slotted steel stud wall was developed using ABAQUS to analyze its fire performance. The model was validated against experiments in this study and other related test data. The FE model was employed to conduct further parametric studies. Parameters include the spalling time of heated gypsum boards, the height of the web, rows of slots, and layers of gypsum boards. The effects of these key factors on the temperatures of the exposed surface, unexposed surface and studs are discussed.