The Gulf Stream (GS) ocean front releases intense moisture and heat to the atmosphere and regulates storm tracks and zonal jets in winter. The large-scale sea surface temperature (SST) anomaly in the central North Atlantic provides important feedback to the atmosphere in winter, but the role played in this feedback by the GS front inside the SST anomaly has not been extensively studied. In this study, two sets of ensemble experiments were conducted using a global community atmosphere model forced by SST in boreal winters from 2000 to 2013. The regional averaged SST and its variation in the experiments were identical, with the only difference being the strength of the SST front in the GS region. The large-scale SST anomaly in the central North Atlantic in our model provides feedback to the atmosphere and excites a wave train that extends across Eurasia. With the inclusion of the strong GS front, the first center of the wave train in the North Atlantic is strengthened by approximately 40%, and the wave activity flux toward downstream is highly intensified. When the large-scale SST anomaly is combined with a strong GS front, greatly increased water vapor is released from the GS region, resulting in a 50% increase in moisture transport toward Western Europe. In this scenario, precipitation and diabatic heating both increase greatly on the western Scandinavian Peninsula. With the release of deep diabatic heating, a strong upward wave activity flux is triggered, and the wave train excited by the large-scale SST variation is significantly intensified. These findings suggest that the strong SST front in the large-scale SST anomaly in the central North Atlantic significantly amplifies its feedback to the atmosphere in winter.