Strong Predictive Effect Research Articles

Association between Frailty and 90-Day Outcomes amongst the Chinese Population: A Hospital-Based Multicentre Cohort Study

Introduction: Frailty has gained increasing attention as it is by far the most prevalent geriatric condition amongst older patients which heavily impacts chronic health status. However, the relationship between frailty and adverse health outcomes in China is far from clear. This study explored the relation between frailty and a panel of adverse health outcomes. Methods: We performed a multicentre cohort study of older inpatients at 6 large hospitals in China, with two-stage cluster sampling, from October 2018 to April 2019. Frailty was measured according to the FRAIL scale and categorized into robust, pre-frail, and frail. A multivariable logistic regression model and multilevel multivariable negative binomial regression model were used to analyse the relationship between frailty and adverse outcomes. Outcomes were length of hospitalization, as well as falls, readmission, and mortality at 30 and 90 days after enrolment. All regression models were adjusted for age, sex, BMI, surgery, and hospital ward. Results: We included 9,996 inpatients (median age 72 years and 57.8% male). The overall mortality at 30 and 90 days was 1.23 and 1.88%, respectively. At 30 days, frailty was an independent predictor of falls (odds ratio [OR] 3.19; 95% CI 1.59–6.38), readmission (OR 1.45; 95% CI 1.25–1.67), and mortality (OR 3.54; 95% confidence interval [CI] 2.10–5.96), adjusted for age, sex, BMI, surgery, and hospital ward clustering effect. At 90 days, frailty had a strong predictive effect on falls (OR 2.10; 95% CI 1.09–4.01), readmission (OR 1.38; 95% CI 1.21–1.57), and mortality (OR 6.50; 95% CI 4.00–7.97), adjusted for age, sex, BMI, surgery, and hospital ward clustering effect. There seemed to be a dose-response association between frailty categories and fall or mortality, except for readmission. Conclusions: Frailty is closely related to falls, readmission, and mortality at 30 or 90 days. Early identification and intervention for frailty amongst older inpatients should be conducted to prevent adverse outcomes.

Hierarchical Neural Prediction of Interpersonal Trust.

Exploring neural markers that predict trust behavior may help us to identify the cognitive process underlying trust decisions and to develop a new approach to promote interpersonal trust. It remains unknown how trust behavior may be predicted early in the decision process. We used electrophysiology to sample the brain activity while participants played the role of trustor in an iterative trust game. The results showed that during the trust generation stage, the trust condition led to higher frontocentral beta band activity related to cognitive inhibition compared to the distrust condition (item level). Moreover, individuals with higher frontocentral beta band activity were more likely to perform trust choices at the single-trial level (individual level). Furthermore, after receiving reciprocity feedback on trialn-1, compared to the betrayal feedback and the distrust choice, the frontocentral beta band oscillation had a stronger predictive effect regarding trust choices on trialn. These findings indicate that beta band oscillations during the decision generation stage contribute to subsequent trust choices.

Androgen receptor gain in circulating free DNA and splicing variant 7 in exosomes predict clinical outcome in CRPC patients treated with abiraterone and enzalutamide

BackgroundAndrogen receptor (AR) signaling inhibitors represent the standard treatment in metastatic castration resistance prostate cancer (mCRPC) patients. However, some patients display a primary resistance, and several studies investigated the role of the AR as a predictive biomarker of response to treatment. This study is aimed to evaluate the role of AR in liquid biopsy to predict clinical outcome to AR signaling inhibitors in mCRPC patients.MethodsSix milliliters of plasma samples were collected before first-line treatment with abiraterone or enzalutamide. Circulating free DNA (cfDNA) and exosome-RNA were isolated for analysis of AR gain and AR splice variant 7 (AR-V7), respectively, by digital droplet PCR.ResultsEighty-four mCRPC patients received abiraterone (n = 40) or enzalutamide (n = 44) as first-line therapy. Twelve patients (14.3%) presented AR gain and 30 (35.7%) AR-V7+ at baseline. Median progression-free survival (PFS) and overall survival (OS) were significantly longer in AR-V7− vs AR-V7+ patients (24.3 vs 5.4 months, p < 0.0001; not reached vs 16.2 months, p = 0.0001, respectively). Patients carrying the AR gain had a median PFS of 4.8 vs 24.3 months for AR normal patients (p < 0.0001). Median OS was significantly longer in AR normal vs patients with AR gain (not reached vs 8.17 months, p < 0.0001). A significant correlation between AR-V7 and AR gain was observed (r = 0.28; p = 0.01). The AR gain/AR-V7 combined analysis confirmed a strong predictive effect for biomarkers combination vs patients without any AR aberration (PFS 3.8 vs 28 month, respectively; OS 6.1 vs not reached, respectively; p < 0.0001).ConclusionsThe present study demonstrates that cfDNA and exosome-RNA are both a reliable source of AR variants and their combined detection in liquid biopsy predicts resistance to AR signaling inhibitors.

Coronavirus Anxiety and Psychological Adjustment in College Students: Exploring the Role of College Belongingness and Social Media Addiction.

The psychological health of people all around the world is severely affected due to the COVID-19 outbreak. This study examined a moderated mediation model in which college belongingness mediated the relationship between coronavirus anxiety and psychological adjustment, and this mediation effect was moderated by social media addiction. A total of 315 undergraduate students (M = 21.65±3.68 years and 67% females) participated in this study. The results demonstrated that college belongingness partially mediated the association between coronavirus anxiety and psychological adjustment. The mediating part from coronavirus anxiety to college belongingness was moderated by social media addiction. In comparison with the high level of social media addiction, coronavirus anxiety had a stronger predictive effect on college belongingness under the low and moderate levels of social media addiction condition. Our findings highlight that college belongingness is a potential mechanism explaining how coronavirus anxiety is related to psychological adjustment and that this relation may depend on the levels of social media addiction.

Effects of security on social trust among Chinese adults: Roles of life satisfaction and ostracism

ABSTRACT The study aims to explore the effect of security on social trust and the roles of life satisfaction and ostracism among Chinese adults. Toward this end, the study recruited 1,206 Chinese adults to complete the Security Questionnaire, Social Trust Questionnaire, Satisfaction with Life Scale, and Ostracism Experiences Scale. Results show that (a) security is positively correlated with social trust among Chinese adults, (b) life satisfaction partially mediates the effect of security on social trust, and (c) ostracism moderates the relationship between security and social trust. Furthermore, findings indicate that security can directly predict social trust as well as indirectly predict social trust through life satisfaction for adults in China. Security has a strong predictive effect on social trust – especially for individuals with low levels of ostracism.

Student subjective wellbeing, school functioning, and psychological adjustment in high school adolescents: A latent variable analysis

Well-being is a multi-faceted construct that encompasses all aspects of healthy and successful human functioning across multiple domains. The purpose of the present study was to investigate the predictive power of student subjective wellbeing on several specific adolescent school and psychological adjustment indicators: school achievement, academic satisfaction, prosocial behavior, and internalizing and externalizing problems. Participants included 223 adolescents, comprising of 54.9% girls, ranging in age from 13 to 18 years (M= 15.67, SD= 1.21). Findings from the LVPA indicated that student subjective wellbeing was significantly associated with youth school functioning and adjustment outcomes, ranging from small-to-large effect size (R2 range = .05 to .42). Student subjective wellbeing had the strongest predictive effect on prosocial behavior, followed by academic satisfaction, psychological health problems, and school achievement. With regard to the first-order models, school connectedness and joy of learning significantly predicted student academic satisfaction, prosocial behavior, and psychological adjustment problems. However, the predictive effect of these variables on student school achievement was non–significant. Educational purpose and academic efficacy were significant predictors of all adolescent outcomes. Taken together, these results suggest that student subjective wellbeing is an essential resource for improving youth academic functioning and psychological health.

Anti-Ro52 antibody is an independent risk factor for interstitial lung disease in dermatomyositis

AimRecent studies have shown that anti-Ro52 antibody is associated with both interstitial lung disease (ILD) and the degree of disease severity in juvenile patients with dermatomyositis (DM). We found that more than half of adult patients with DM were positive for anti-Ro52 antibody. In this study, we analysed the correlation between anti-Ro52 antibody and ILD in adult patients with DM. MethodSerum samples were collected from 153 adult inpatients with DM, at the First Medical Centre of PLA General Hospital, Beijing, China, who met the classification criteria of idiopathic inflammatory myopathies from March 1, 2016 to September 30, 2019. The patients were followed up to May 31, 2020. Immunoblotting was used to detect 16 types of myositis-specific autoantibodies (MSAs) and myositis-associated autoantibodies (MAAs) from serum samples. High-resolution computed tomography (HRCT) was used to calculate the ILD score, and tumours were screened. Clinical data and HRCT scores were evaluated and analysed retrospectively. ResultsOur results showed that anti-Ro52 antibodies were the most commonly found antibodies in patients with DM, with a positive rate of 52.9%. Anti-Ro52, anti-aminoacyl-tRNA synthetase (anti-ARS), and anti-melanoma differentiation-related gene 5 (anti-MDA5) antibodies were found to be risk factors for ILD development. Anti-Ro52 antibodies had a strong predictive effect on ILD in patients with DM. ConclusionThe occurrence of ILD is highly likely in patients with DM who are positive for the anti-Ro52 antibodies. Thus, anti-Ro52 antibodies is an independent risk factor for ILD in patients with DM.

Association between obesity and oligomenorrhea or irregular menstruation in Chinese women of childbearing age: a cross-sectional study

Objective In this study, we aimed to investigate the relationship between body mass index (BMI), waist circumference (WC) or waist-to-hip ratio (WHR) and oligomenorrhea or irregular menstruation in Chinese women of childbearing age. Methods A total of 1,423 Han women aged 19–39 years who were routinely examined at the Physical Examination Center of Peking University People's Hospital were enrolled by convenience sampling method. All participants were asked to fill up menstrual questionnaires. Binary logistic regression models were used to assess the odds ratio (OR) of different BMI, WC and WHR groups for the prevalence of oligomenorrhea and irregular menstruation. Moreover, we used the ROC curves to compare the predictive effects of BMI, WC and WHR on oligomenorrhea and irregular menstruation. Results Among the 1,423 participants, 93 women (6.5%) had BMI ≥ 30 kg/m2, 6.5% of the participants had oligomenorrhea, and 22.6% had irregular menstrual menstruation. Overall, those with BMI ≥30 kg/m2 (OR = 2.543; 95%CI 1.332–4.856; p = .005) or WC ≥ 90 cm (OR = 2.023; 95%CI 1.198–3.416; p = .008) were more likely to have long menstrual cycle. The prevalence of irregular menstruation was higher in the BMI ≥30 kg/m2 (OR = 2.509; 95%CI 1.591–3.958; p < .001), WC ≥ 90 cm (OR = 2.299; 95%CI 1.619–3.265; p < .001) and WHR ≥ 0.86 (OR = 1.739; 95%CI 1.293–2.339; p < .001) groups. The ROC curve showed that all three anthropometric indices had predictive effect, while there was no significant difference in predicting oligomenorrhea. WC was a better predictor for irregular menstruation compared with BMI. Conclusions Obesity, oligomenorrhea and irregular menstruation were common in Chinese women of childbearing age, and obesity was associated with oligomenorrhea and irregular menstruation. Abdominal obesity might have a stronger predictive effect on irregular menstruation.

Network Analyses of Maternal Pre- and Post-Partum Symptoms of Depression and Anxiety.

BackgroundMaternal mental health problems often develop prenatally and predict post-partum mental health. However, the circumstances before and following childbirth differ considerably. We currently lack an understanding of dynamic variation in the profiles of depressive and anxiety symptoms over the perinatal period.MethodsDepressive and anxiety symptoms were self-reported by 980 women at 26-week pregnancy and 3 months post-partum. We used network analysis of depressive and anxiety symptoms to investigate if the symptoms network changed during and after pregnancy. The pre- and post-partum depressive-anxiety symptom networks were assessed for changes in structure, unique symptom-symptom interactions, central and bridging symptoms. We also assessed if central symptoms had stronger predictive effect on offspring’s developmental outcomes outcomes at birth and 24, 54, and 72 months old than non-central symptoms. Bridging symptoms between negative and positive mental health were also assessed.ResultsThough the depressive-anxiety network structures were stable during and after pregnancy, the post-partum network was more strongly connected. The central depressive-anxiety symptoms were also different between prenatal and post-partum networks. During pregnancy, central symptoms were mostly related to feeling worthless or useless; after pregnancy, central symptoms were mostly related to feeling overwhelmed or being punished. Central symptoms during pregnancy were associated with poorer developmental outcomes for the child. Anxiety symptoms were strongest bridging symptoms during and after pregnancy. The interactions between negative and positive mental health symptoms were also different during and after pregnancy.ConclusionsThe differences between pre- and post-partum networks suggest that the presentation of maternal mental health problems varies over the peripartum period. This variation is not captured by traditional symptom scale scores. The bridging symptoms also suggest that anxiety symptoms may precede the development of maternal depression. Interventions and public health policies should thus be tailored to specific pre- and post-partum symptom profiles.

Who Wants To Be a Politician? Basic Human Values and Candidate Emergence in the United Kingdom

AbstractPublic faith in politicians and associated systems of governance is desperately low. At the same time, public opinion of politicians is characterized by a vernacular of psychological accusations pertaining to greed, self-interest and careerism. This article tests the verity of these claims by comparing quantitative data on the Basic Human Values (Schwartz 1992) of 106 UK Members of Parliament (MPs) and 134 unsuccessful parliamentary candidates with data collected from the British public in the seventh wave of the European Social Survey. It explores (a) how politicians differ psychologically from those they govern and (b) how personality characteristics such as basic values inform candidate emergence. The study finds that politics is a profession few ‘ordinary’ people care to enter. MPs attribute significantly more importance to Self-Transcendence values than the comparatively conservative population they govern, but the relative importance they ascribe to Power values seems to have an equally strong predictive effect on candidate emergence.

Positive lymph node ratio as a novel indicator of prognosis in gastric signet ring cell carcinoma: a population-based retrospective study.

BackgroundLymph node status has a strong predictive effect on the prognosis of all patients with gastric cancer. It is unclear whether the positive lymph node ratio (PLNR) is a reliable prognostic factor for gastric signet ring cell carcinoma (SRCC).MethodsPatients with SRCC were obtained from the Surveillance, Epidemiology and End Results (SEER) database for the years 1998–2013. Cutoff values of positive lymph node ratio (PLNR) were decided using X-tile program. Survival was determined using the Kaplan-Meier method. Univariate and multivariate analyses were used to identify prognosticator of gastric signet ring cell carcinoma.ResultsA total of 1,884 cases were identified. 0.8 as the optimal cutoff value to separate the patients into high and low risk subsets in accordance of cancer-caused survival in SRCC patients (the number as 0.8, P<0.0001). Patients with PLNR >0.8 remained to have a poorer prognosis compared with those with PLNR <0.8 as shown by both OS (HR =2.083, 95% CI: 1.862–2.33, P<0.001) and CSS (HR =2.052, 95% CI: 1.802–2.336, P=0.014) in the multivariate cox regression model.ConclusionsPLNR is of great significance in the evaluation of prognosis for patients with SRCC.

Comparison of child report and parent-proxy report using PROMIS-25 in the chiropractic care for children

• Parents and their children perceived improvements in the child’s quality of life with chiropractic care. • The majority of parents assess the change/improvements in their child’s quality of life similarly to their children. • The number of days from baseline to comparative assessment of quality of life was identified as an important factor in the differences in perceived change in anxiety, peer-relationships, mobility, and pain interference. Baseline quality of life assessments were also identified as having a strong predictive effect on the difference in perceived change in quality of life.

The Relationship Between Burnout and Psychological Flexibility Processes in Healthcare Professionals

Healthcare professionals have been the most studied professional organization since the concept of professional burnout first emerged. Working conditions stand out as the factor that most affects burnout in the studies conducted at the health sector, which is one of the professions where humanitarian contact is the most intense. In our study, the relationships of psychological factors and sociodemographic factors with burnout parameters were examined. The research was conducted between May 2018 and September 2018, with 226 participants working in Istanbul who completing the scales properly. A sociodemographic form to determine the characteristics of the work environment together with personal factors such as age and gender, Acceptance and Action Questionnaire-II (AAQ-II) to evaluate psychological flexibility processes, Self-as-Context Scale (SAC), and Valued Living Questionnaire (VLQ) to evaluate one's attitude to value areas was used as data collection tools. As a result of the evaluation of the data, it was observed that the young age, the number of patients cared for and the number of monthly seizures were associated with an increase in burnout and having a child was associated with a decrease in burnout level. In correlation analysis, it was shown that the relationship between burnout parameters and psychological flexibility processes was stronger than their relationship with sociodemographic variables. As a result of the regression analysis, it was observed that the most powerful predictor of burnout was experiential avoidance. It was calculated that high self-as-contex and value-oriented attitude towards life significantly predicted personal fulfillment perception. As a result, it was observed that psychological flexibility variables had a stronger predictive effect on burnout compared to sociodemographic characteristics. The results of the study show that interventions that will increase the psychological flexibility of healthcare professionals as well as improving their working conditions will be valuable.

An Empirical Study Research of the Relationship between Stressors and Work Engagement in Hotel

This study explored the relationship between the stressors and the work engagement of hotel staff based on the psychological capital view. 319 valid questionnaires were retrieved and we used structural equations for statistical analysis. The findings show that: (1) Hindrance stressors perceived by hotel employees are significantly negatively correlated with employees' psychological capital and work engagement; the correlation between challenge stressors and employee psychological capital and work engagement are not significant. (2) Psychological capital and its sub-dimensions are positively correlated with the work engagement of employees, and the dimension resilience has a strongest predictive effect on the work engagement of hotel employees. (3) Psychological capital can fully mediate the negative impact of hindrance stressors on hotel employees' work engagement. Introduction

School belonging in adolescents: Exploring the associations with school achievement and internalising and externalising problems

Aim(s)School belonging is critically important for both school-based outcomes and psychosocial adjustment of adolescents. The purpose of this study is to present further validation evidence for the School Belongingness Scale (SBS) and investigate the predictive effect of the school belonging on school achievement and mental health outcomes (i.e. internalising and externalising problems) in elementary school students.MethodParticipants included 223 students from a public elementary school in an urban city, Turkey (51.1 per cent female and 48.9 per cent male ranging in age from 10 to15 years (M = 12.09; SD = 1.03)).FindingsFindings of the study revealed that the scale had excellent data-model fit statistics, supporting the higher-order school belonging latent structure, comprising of two first-order constructs (i.e. social inclusion and exclusion), adequate–to–strong factor loadings, and adequate latent construct (H) and internal (α) reliability coefficients. Further outcomes indicated that school belonging had a strong predictive effect on school achievement, internalising and externalising behaviours among elementary school students.LimitationsWhile the study utilised a cross-sectional approach and is unable to provide causality, the preliminary findings have implications for schools and future research.ConclusionsThe study results provide further evidence supporting the impacts of school belonging in promoting youth academic functioning and mental health.

Identifying Predictors of Stress and Job Satisfaction in a Sample of Merchant Seafarers Using Structural Equation Modeling.

Background: Seafarers are amongst occupational groups with the highest risk for stress, a factor known to impact on mental health. Psychological issues such as depression, anxiety, suicide, and alcohol or drug dependence are recognized health problems within the maritime sector. The primary aim of this study was to identify which individual and occupational factors, known to impact on psychological functioning across the maritime industry and other sectors, best predict perceived stress and job satisfaction among a sample of merchant seafarers.Methods: Secondary data analysis was conducted using a work experiences and attitudes questionnaire administered by a large shipping company to seafarers within their organization. Structural equation modeling was conducted using a proposed theoretical model of perceived stress and job satisfaction in a sample of merchant seafarers.Results: While the structural equation model produced acceptable fit to the sample data according to numerous goodness-of-fit statistics, the comparative fit index and Tucker-Lewis index results indicated less than satisfactory model fit. The model explained 23.8% of variance in the criterion variable of perceived stress, and the strongest predictive effect was for dispositional resilience. The model explained 70.6% of variance in the criterion variable of job satisfaction, and the strongest predictive effect was for instrumental work support.Conclusion: When addressing the psychosocial well-being of merchant seafarers, findings of this study suggest that dispositional resilience may be a particularly important factor with regards to perceived stress, while instrumental work support appears to be a critical factor in relation to job satisfaction. Importantly, however, an overall work environment that is perceived by employees as supportive, equal and just is a cornerstone for the psychosocial well-being of seafarers.

대학교양체육수업에서 학생들이 인식한 기대가치이론 변인들이 체육활동 지속의도에 미치는 역할

The purpose of this study was to verify the influences of expectancy-value theory on persistence intention of physical activity among university students participating in physical education classes. A total of 814 students took part in the activities such as fitness, yoga, tennis, golf, and badminton for one semester in 2017. The participants completed self-reported questionnaires assessing variables including expectancy beliefs for ability and success, importance, interest, and usefulness for activities in physical education classes. The results drawn from multiple linear regression analyses showed all variables played a significant role in predicting for persistence intention on physical activity. The coefficient of determination of the analyzed model revealed about 40%, which indicated a strong predictive effect of expectancy-value model. The study findings based on expectancy-value theory perspective provide empirical support for promoting physical activity among university students, which in turn produces educational implications for university physical educators.

Psychometric properties of the Norwegian version of the hospital survey on patient safety culture in a prehospital environment

BackgroundTo develop a culture of patient safety in a regime that strongly focuses on saving patients from emergencies may seem counter-intuitive and challenging. Little research exists on patient safety culture in the context of Emergency Medical Services (EMS), and the use of survey tools represents an appropriate approach to improve patient safety. Research indicates that safety climate studies may predict safety behavior and safety-related outcomes. In this study we apply the Norwegian versions of Hospital Survey on Patient Safety Culture (HSOPSC) and assess the psychometric properties when tested on a national sample from the EMS.MethodsThis study adopted a web based survey design. The Norwegian HSOPSC has 13 dimensions, consisting of 46 items, in addition to two single-item outcome variables. SPSS (version 21) was used for descriptive data analysis, estimating internal consistency, and performing exploratory factor analysis. Confirmatory factor analysis (CFA) was applied to test the dimensional structure of the instruments using Amos (version 21).ResultsN = 1387 (27%) EMS employees participated in the survey. Overall, acceptable psychometric properties were observed, i.e. acceptable internal consistencies and construct validity. The patient safety climate dimensions with highest scores (number of positive answers) were “teamwork within units” and “manager expectations & actions promoting patient safety”. The dimension “hospital management support for patient safety” had the lowest score.ConclusionsThe results provided a validated instrument, the Prehospital Survey on Patient Safety Culture (PreHSOPSC), for measuring patient safety climate in an EMS setting. In addition, the explanatory power was strong for several of the outcome dimensions; i.e., several of the safety climate dimensions have a strong predictive effect on outcome variables related to employees’ perceptions on patient safety and safety-related attitude.

Comparison of the Technique of the Football Quarterback Pass Between High School and University Athletes.

Toffan, A, Alexander, MJL, and Peeler, J. Comparison of the technique of the football quarterback pass between high school and university athletes. J Strength Cond Res 32(9): 2474-2497, 2018-The purpose of the study was to compare the most effective joint movements, segment velocities, and body positions to perform the fastest and most accurate pass of high school and university football quarterbacks. Secondary purposes were to develop a quarterback throwing test to assess skill level, to determine which kinematic variables were different between high school and university athletes, and to determine which variables were significant predictors of quarterback throwing test performance. Ten high school and 10 university athletes were filmed for the study, performing 9 passes at a target and 2 passes for maximum distance. Thirty variables were measured using Dartfish Team Pro 4.5.2 video analysis system, and Microsoft Excel was used for statistical analyses. University athletes scored slightly higher than the high school athletes on the throwing test; however, this result was not statistically significant. Correlation analysis and forward stepwise multiple regression analysis were performed on both the high school players and the university players to determine which variables were significant predictors of throwing test score. Ball velocity was determined to have the strongest predictive effect on throwing test score (r = 0.900) for the high school athletes; however, position of the back foot at release was also determined to be important (r = 0.661) for the university group. Several significant differences in throwing technique between groups were noted during the pass; however, body position at release showed the greatest differences between the 2 groups. High school players could benefit from more complete weight transfer and decreased throw time to increase throwing test score. University athletes could benefit from increased throw time and greater range of motion in external shoulder rotation and trunk rotation to increase their throwing test score. Coaches and practitioners will be able to use the findings of this research to help improve these and related throwing variables in their high school and university quarterbacks.

Value of 18F-FDG PET/CT in evaluation of curative effect and progression-free survival on lymphoma

Objective To evaluate the value of 18F-fluorodeoxyglucose (FDG) PET/CT in evaluation of curative effect and progression-free survival (PFS) for lymphoma patients. Methods The data of 85 lymphoma patients were retrospectively analyzed. Before and after 4-8 cycles standardized chemotherapy, the patients were evaluated with 18F-FDG PET/CT. The two-year PFS rate was compared. The value of 18F-FDG PET/CT in evaluation of curative effect and PFS for lymphoma patients received chemoradiotherapy was analyzed. Results The non Hodgkin lymphoma (NHL) was the common type, and the common pathogenic sites were head and neck lymph nodes, mediastinum and retroperitoneum. The majority of patients were accompanied with spleen enlargement and local lesions with high metabolism. The complete remission (CR) rate of Hodgkin lymphoma (HL) patients in PET/CT negative group was significantly higher than that in positive group (86.4% vs. 42.9%, P=0.038). The two-year PFS rates in PET/CT positive group and negative group were 42.9% and 81.8%, and the difference was statistically significant (χ2=7.70, P=0.006). Thirty-five NHL patients achieved CR, 13 achieved partial remission (PR), and 8 achieved stable disease (SD) or disease progression (PD). The two-year PFS rates in the CR group, PR group, SD or PD group were 89.7%, 65.3% and 19.4% respectively, and the difference was statistically significant (χ2=12.41, P=0.002). PET/CT imaging had a strong PFS predictive effect on T cell lymphoma (TCL) patients (χ2=13.85, P=0.001) and diffuse large B cell lymphoma (DLBCL) patients (χ2=13.51, P=0.001), and had no predictive effect on follicular lymphoma (FL) patients (χ2=4.63, P=0.099). Conclusion 18F-FDG PET/CT can evaluate the curative effect of lymphoma effectively and early predict prognosis, and has great guiding significance in choosing therapeutic schedule. Key words: Lymphoma; Fluorodeoxyglucose F18; Positron-emission tomography; Tomography, X-ray computed; Prognosis; Efficacy evaluation