Strict Diet Research Articles

Prurigo Pigmentosa Associated with a Ketogenic Diet in a Romanian Patient: A Case Report

Background/Objectives: Prurigo pigmentosa (PP) is a rare inflammatory dermatosis characterized by recurrent pruritic eruptions resolving with reticulated hyperpigmentation. Initially described in young Asian women, PP is increasingly reported worldwide, often linked to ketosis-inducing factors such as low-carbohydrate diets. This report documents the first case of PP in a Romanian patient and highlights the importance of recognizing the condition in diverse populations. Methods: We describe a 16-year-old girl with a six-month history of pruritic eruptions on the neck, trunk, shoulders, and thighs. A detailed clinical assessment was conducted, including dietary history, physical examination, laboratory evaluation of urinary ketones, and skin biopsy for histopathological analysis. Results: Clinical examination revealed erythematous papules and plaques with peripheral pustules and post-inflammatory hyperpigmentation. Substantial weight loss and elevated urinary ketone levels suggested dietary-induced ketosis from a strict low-carbohydrate diet. Histopathological findings confirmed the diagnosis of PP. The patient’s skin lesions resolved following carbohydrate reintroduction and doxycycline therapy. Conclusions: This case highlights the association between ketosis and PP, emphasizing the importance of thorough dietary history-taking and histopathological confirmation for accurate diagnosis. As ketogenic diets become more popular globally, heightened awareness of PP is essential to ensure timely diagnosis and effective management.

A RARE CASE REPORT : MACULAR HAEMORRHAGE AS A COMPLICATION OF MEGALOBLASTIC ANAEMIA

We report a case of 17-year-old female patient with sudden, painless, non progressivediminished vision in both eyes (L>R)(best corrected visual acuity in right eye- 6/18 and left eye - 3/60) . She was on a strict vegetarian diet for a long time. The ophthalmological evaluation revealed bilateral pallor and retinal haemorrhages. She was diagnosed to have severe megaloblastic anaemia secondary to nutritional deficiency with associated anaemic retinopathy.After treatment with intramuscular B12 supplementation, dramatic resolution of retinal haemorrhages and improvement in visual acuity was observed after 6 weeks .This case documents the rare occurrence of bilateral sub internal limiting membrane haemorrhages with megaloblastic anaemia with thrombocytopaenia and other retinal features of anaemic retinopathy.

Comparison of efficacy of low glycemic index treatment and modified Atkins diet among children with drug-resistant epilepsy: A randomized non-inferiority trial.

The ketogenic diet has been the mainstay of treatment of drug-resistant epilepsy (DRE). No comparative trials have been conducted to assess the efficacy of the two less strict ketogenic diets: modified Atkins diet (MAD) and low glycemic index treatment (LGIT). This study assesses the non-inferiority of LGIT compared with MAD. This was an open-label randomized non-inferiority trial. Children with DRE were randomized to receive either MAD or LGIT as an add-on to anti-seizure medications. The primary endpoint was percentage seizure reduction at the end of 24 weeks of therapy compared to the baseline. The non-inferiority margin of -15% was predefined to calculate the sample size. Ninety-one children were enrolled and randomized to receive either MAD (n = 45) or LGIT (n = 46). Intention-to-treat analysis done at the end of 24 weeks of therapy showed a mean (±standard deviation [SD]) percentage seizure reduction of 60.7% (±41.3) in the MAD sub-group and 57% (±39.4) in the LGIT sub-group (p = 0.664). The absolute difference between the means of percentage seizure reduction was -3.7 (-20.5 to 13.2) and crossed the non-inferiority margin. Ten children in the MAD group and nine children in the LGIT group did not complete 24 weeks of therapy. Adverse effects were comparable between the arms (MAD, 66.6%; LGIT, 50%), although serious adverse effects were higher in the MAD arm. The most common adverse effect was decreased acceptance (24.2%) followed by decreased satiety (9.9%), vomiting (9.9%), weight loss (5.5%), constipation (5.5%), and diarrhea (3.3%). Dyslipidemia was more commonly seen in the MAD group (MAD, six; LGIT, one). One death in the LGIT arm was unrelated to therapy. Although there was no statistically significant difference in improvement in cognition, behavior, and quality of life scales, improvement was noted from baseline scores. LGIT may be non-inferior to MAD in the treatment of children with DRE with the advantage of increased acceptance and fewer adverse effects.

Harmful metabolic acidosis in children treated by ketogenic diet during prolonged general anesthesia for epilepsy surgery: A single center experience.

Management of ketogenic diet (KD) in case of prolonged anesthesia in children. We conducted a retrospective study in the pediatric neurosurgery department of Rothschild Hospital Foundation in France. All the children who underwent long term anesthesia (>4h) in case of neurosurgery for drug resistant pediatric epilepsy surgery between September 2020 and January 2024 were included, excluding patients with suspected metabolic disorder or without blood sample. Children were analyzed in three subgroups: Children under regular diet before surgery constituted the Non-KD group; strict maintenance of KD with no carbohydrate intake during surgery constituted the KD-S group (stringent); carbohydrate intravenous intake during surgery in a patient treated by KD represented the KD-B group (broken). 22 patients were included, among whom 6 under ketogenic diet (KD). After 4h of anesthesia, children maintained in strict ketogenic diet (KD-S, n=3) exhibited non-lactic metabolic acidosis (pH 7.13 vs 7.34, p=1.38x10-9) associated with an increased anionic gap (17.1mM vs 9.6mM, p=1.58 x10-4). Current recommendations for anesthesia during long term anesthesia (>4h) with strict no-carbohydrate intake during anesthesia in case ok KD may be at risk of life-threatening metabolic acidosis, in a context of absence of protocolized monitoring of variations in hyperketosis throughout a prolonged fast. A KD-management protocol, including routine monitoring of ketosis in addition to usual monitoring (lactacidemia, kaliemia and glycemia), and low carbohydrates intravenous perfusion throughout prolonged general anesthesia, should be implemented throughout prolonged general anesthesia, especially for infants younger than 2 years.

Comparison of Hematological Parameters and the Associated Factors Among Women with and without Breast Cancer: A Case-Control Study.

Breast cancer (BC) is the most popular and dangerous cancer, with a high mortality rate. Hematological parameters are often used in routine diagnosis of numerous disorders. Therefore, the study aimed to evaluate hematological parameters amongst women with and without BC. Briefly, 200 blood samples (100 cases and 100 controls) were collected at Life Center of Breast Cancer Control, Ibb City, Yemen. The whole blood samples were tested immediately for complete blood count (CBC) parameters. Socio-demographic and reproductive characteristics were collected by using a standardized questionnaire. Kolmogorov-Smirnov test, Unpaired t-test, Mann-Whitney test, Fisher's exact test and chi-square test for trends were calculated using GraphPad Prism 8.0.1. P-values ≤0.05 were statistically significant. The mean and standard deviation (SD) revealed significant differences between BC group and the healthy control group attributed to the variables of age (P<0.0001), weight (P<0.0001), residence (P=0.0218), employment state (P<0.0001), economic state (P=0.0003), education levels (P<0.0001), regular exercise (P<0.0001) and a strict diet (P<0.0008). Marital state, marital age, number of births, and use of contraceptives demonstrated statistical significance (P<0.0001, P=0.0008, P=0.0009, and P<0.0001, respectively). Additionally, Hb, RBCs, WBCs count, neutrophils, lymphocytes and monocytes displayed significant differences (P=0.0393, P=0.0045, P=0.0327, P=0.0441, P=0.0098 and P<0.0001, respectively). Hb, RBCs, WBCs, neutrophils, lymphocytes, monocytes and other parameters scored high points of evidence for BC surveillance. Further studies are required to evaluate hematological parameter differences and biochemical parameters after or during chemotherapy or mastectomy.

Familial chylomicronemia: New perspectives.

Familial chylomicronemia syndrome (FCS) is a very rare, underdiagnosed disorder that can cause abdominal pain and recurrent pancreatitis from childhood -potentially life-threatening- and chronic complications such as diabetes mellitus and exocrine pancreatic insufficiency. FCS affects the quality of life and mental health of those who suffer from it, aspects that must be taken into account in its treatment, based on a strict low-fat diet, which is difficult to adhere to and persist. People with FCS lack the lipolytic capacity to hydrolyze triglycerides (TG) and have a minimal or null response to conventional lipid-lowering treatments. ApoCIII antagonists, specifically volanesorsen, olezarsen and ARO-APOC3, are the most promising drugs to reduce TG concentrations in patients with FCS. Anti-ANGPTL3 therapies appear to be less effective. More clinical trials and new pharmacological treatments are needed to improve the quality of life and prognosis of people with FCS.

The Role of Exogenous Ketones in Road Cycling: Evidence, Mechanisms, and Performance Claims

Background: Ketone body supplementation has emerged as a potential ergogenic aid in cycling. Exogenous ketones, primarily in the form of beta-hydroxybutyrate, offer an alternative fuel source, bypassing the need for strict ketogenic diets. However, the science surrounding their efficacy remains complex, with mixed field findings and unexplored mechanisms. Methods: A narrative review of the current literature was conducted, synthesizing studies on the metabolic and cognitive effects of ketone bodies in cycling. The review included an examination of human and mechanistic studies, along with emerging hypotheses on ketone bodies and their role in modulating red blood cell production and recovery processes. Results: Ketone body supplementation can theoretically spare glycogen, reduce muscle protein breakdown, enhance fat oxidation, and improve recovery by mitigating oxidative stress and inflammation. Additionally, ketone bodies may support cognitive function, reducing perceived mental fatigue. Preliminary evidence also suggests a potential role in modulating erythropoietin levels through histone acetylation, though further research is needed to establish its impact on oxygen delivery. Despite the theoretical potential, the practical assessment of field studies shows disappointing effects on performance from ketone body supplementation. Conclusions: While ketone bodies offer several potential benefits for cyclists, the variability in individual responses, lack of long-term data, and inconsistent findings in performance studies highlight the need for further research. Optimizing dosage, timing, and understanding the broader implications of ketone body supplementation will be crucial for their practical application in cycling.

Malnutrition and its Risk Factors in Renal Patients on Dialysis

Patients with end stage kidney disease (ESKD) on hemodialysis (HD) should follow a strict diet during the inter-dialytic period(1). Compliance to treatment, including diet, is key for optimal disease management and health outcomes and to protect against malnutrition(2,3). The objective of this study was to assess renal nutrition-related knowledge, compliance with dietary guidelines, adherence to treatment and risk of malnutrition among patients with ESKD in Lebanon.A convenience sample of 119 patients with ESKD on HD was recruited from the dialysis units of the Lebanese American University Medical Center-Rizk Hospital (LAUMC-RH) and Hammoud Hospital University Medical Center (HHUMC) in Lebanon. Demographic characteristics, 24 hour-recall and a validated food frequency questionnaire(4) were collected from participants, while anthropometrics including weight status in the past 3 months, as well as biochemical data were collected from medical charts. Bioelectrical impedance tests were conducted on the patients, 30 mins after HD hemodialysis session, to assess body composition. Nutrition knowledge was assessed using a validated questionnaire(5), whereby “poor knowledge” corresponds to &lt;70% correct answers. Compliance to treatment (HD sessions, medications, fluids, and diet) was collected from participants using the End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ)(6)) (Kim et al., 2010) and scored using the tool guide. Accordingly, adherence was classified as “poor” (scores &lt;500), “moderate” (scores: 500-799), or “good” (scores: 800-1000).100 of the 119 participants (85.5%) were found to have malnutrition according to the Global Leadership Initiative on Malnutrition (GLIM) criteria(7). Malnourished patients were mostly found with lower education (57%), poor nutrition knowledge (68%), poor to moderate overall compliance (82%), and with no adequate caloric intake (67%). Weight loss was the most common phenotypic criterion among malnourished patients, whereby 22% of malnourished patients had weight loss of &gt; 3Kg in the past 3 months. Malnourished patients with weight loss had a higher (p = 0.008) prevalence of poor overall compliance (36%), compared to those with mild or no weight loss (14%). Additionally, malnourished people with poor compliance tended to be younger (&lt;55 years of age) and with lower levels of income and education (p&lt;0.05).Malnutrition rates are alarmingly high among patients with ESKD in our sample and are linked with low nutrition knowledge and poor adherence to treatment, including dietary compliance. Future studies with a larger more representative cohort are required to confirm our results. Accordingly, intervention trials targeting knowledge and adherence among ESKD patients in Lebanon are warranted to prevent malnutrition and to achieve better clinical outcomes.

One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study.

Background/Objectives: This study evaluated the impact of continuous positive airway pressure (C-PAP) therapy combined with a rigorous diet regimen on obese patients with obstructive sleep apnea syndrome (OSAS). Methods: Sixty obese patients (BMI ≥ 30) diagnosed with severe OSAS were recruited in order to establish the evaluation of CPAP therapy with different extents of adherence to a rigorous diet regimen. After one year, significant improvements were observed. Results: BMI reduced by 12.32%, apnea-hypopnea index (AHI) by 22.04%, oxygen desaturation index (ODI) by 15.87%, total sleep time with oxygen saturation below 90% (TST90%) by 25.2%, and Epworth Sleepiness Scale (ESS) scores by 21.74%. Patients were, then, divided into three groups, based on adherence to the restricted diet, as well as to the correct use of the nocturnal C-PAP, showing different reductions in BMI, AHI, ODI, TST90%, and ESS, according to their adherence, based on the sum of % reduction in BMI + AHI into three groups. Conclusions: These findings underscore the effectiveness of combining C-PAP therapy with a strict diet in improving OSAS symptoms and overall health in obese patients. Future studies with larger cohorts and longer follow-up periods are needed to confirm these results and explore the long-term benefits of this integrated approach.

S1419 Following a Stricter Diet Is Associated With Higher Confidence in Managing IBD But Also a Higher Perceived Diet Burden

S1419 Following a Stricter Diet Is Associated With Higher Confidence in Managing IBD But Also a Higher Perceived Diet Burden

The Effect of Carnitine Supplementation on Cardiac Function and Ketogenic Diet Effectiveness in Patients with Drug Resistant Epilepsy on Ketogenic Diet

Abstract Background Ketogenic Diet (KD) is gaining attention as a management line in childhood drug resistant epilepsy (DRE) and it is an effective line of therapy for DRE in children. KD is a strict diet consisting of minimal carbohydrate and adequate protein intake with increased fat content. Although KD is effective for epilepsy management, it is deficient in several minerals, vitamins, and trace elements, which can lead to several early and late complications. Objective To demonstrate the effect of carnitine supplementation on cardiovascular functions in patients with DRE on KD and to highlight the effect of carnitine supplementation on efficacy of KD in seizure control. Methods This study was a clinical trial (Trial Design: Parallel 1:1) which included 52 patients with DRE on KD following up at Pediatric Neurology and Clinical Nutrition Outpatient Clinics at Ain Shams University children`s Hospital (or admitted as inpatient) in the period from March 2022 to October 2022 Results There was a statistically significant decrease in the CSSS after 6 months compared to initial presentation among the L-carnitine supplemented group. After 6 months of L-carnitine supplementation, the supplemented group showed significant increase in interventricular wall thickness diameter (IVSD) and significant increase in posterior wall thickness (PWT). Left ventricular end-diastolic diameter (LVED) and left ventricular (LV) mass index showed also increased but didn’t reach significance statistically after L- carnitine supplements. There was no statistically significant difference between carotid intima-media thickness CIMT at initial presentation and after 6 months among L-carnitine supplemented group. Conclusion After six months of L-carnitine supplementation in patients with DRE on KD, there was improvement in the frequency and duration of convulsions among L-carnitine group. Regarding ECHO finding, L-carnitine group showed increase in interventricular wall thickness diameter (IVSD) and posterior wall thickness (PWT). Left ventricular end-diastolic diameter (LVED) and left ventricular (LV) mass index also showed increases but didn’t reach statistical significance after L- carnitine supplementation. There was no statistically significant difference in carotid intima-media thickness CIMT at initial presentation and after 6 months among L-carnitine supplemented group.

Monitoring the Quality of Life and the Relationship between Quality of Life, Dietary Intervention, and Dietary Adherence in Patients with Coeliac Disease.

Inadequate adherence to a gluten-free diet in coeliac disease triggers autoimmune reactions and can reduce the quality of life. The strict diet requires constant vigilance, which can cause psychological distress. Our research aimed to assess the quality of life in adult patients with coeliac disease and to find a correlation between quality of life, dietary intervention, and adherence. The study included 51 adult patients with coeliac disease who completed a quality-of-life questionnaire. Adherence was assessed using serological tests and a dietary adherence test. The patients were divided into two groups: those on a gluten-free diet for at least three months (Group I) and newly diagnosed patients (Group II). Group I showed a significant decrease in the dysphoria subscale of the quality-of-life test between the first and last surveys. Poor quality of life was associated with worse adherence in Group II. A higher "Health concerns" quality of life subscale score was also associated with worse adherence in Group II. Our results suggest that dietetic care may be beneficial for patients with coeliac disease by reducing dysphoria. We recommend regular and long-term dietary monitoring from diagnosis to ensure adherence to a gluten-free diet and to maintain quality of life.

A Review On: Role of Pearl Millet Derived Gluten Free Product and Its Benefit in Treating Iron Deficiency Anaemia in Celiac Patients

Hidden hunger is a global issue and is coming up as a alarming problem for mankind. At the same time world’s most popular countries data showed the occurrence of Celiac Disease, mostly popular in India, Brazil, Russia also in US. 5-8 million people of India is expected to have celiac disease which is not a number can be ignored. The Strict Gluten Free Diet (GFD) is the only therapy intended for celiac patients, as a result most of the patient suffers from Iron Deficiency Anemia which is one of the most reported additional intestinal manifestations of celiac disease. Today’s market lacks the proper gluten free diet products. Most of them are either too costly or not nutrient dense. Millets being a Nutri cereal and old-style staple food of the dry land areas of the world can work as wonder in treating this problem. Among millets, Pearl millet is famous and important grain in the dry and semitropical areas of many developing countries. Proper fortification, enrichment and introducing millets in the plate of celiac patients are showing beneficial result in improving their health status. Our present study will review the part of pearl millet derived product and their efficacy, in treating iron deficiency anemia in celiac patients.

RELATIONSHIP BETWEEN KNOWLEDGE LEVELS AND EFFORTS TO PREVENT GASTRITIS RECURRENCE AMONG TEENAGERS IN RW 006 OF SEPANJANG JAYA, RAWALUMBU DISTRICT IN 2022

Gastritis is a disease that often triggers recurrence. One of the factors that cause recurrence is the patient's lifestyle as a result of lack of knowledge in preventing the recurrence of gastritis. Busy activities at school, dense social activities, and a strict diet to maintain appearance are common characteristics of lifestyle mistakes among teenagers. Lack of knowledge and understanding of unhealthy lifestyles causes gastritis in them. This research was conducted using a quantitative method. The design in this study used Analytical Observation with a Cross Sectional approach. The research sample consisted of 51 teenagers aged 14 -19 years in RW 006 who were selected using purposive sampling technique. Bivariate analysis was carried out through the Chi Square statistical test. A p-value of (0.000) &lt; (0.05) was obtained. This shows that Ho is rejected and Ha is accepted. The results of the bivariate analysis showed 42 respondents had a good level of knowledge, with 34 respondents (66.7%) aware of relapse prevention efforts. Based on the results of the study, there is a significant relationship between the level of knowledge and efforts to prevent recurrence of gastritis among teenagers in RW 006 of Sepanjang Jaya, District Rawalumbu in 2022.

Trends in Plant-Based Diets and the Associated Health Characteristics among Canadians.

In Canada, unhealthy dietary patterns comprise diets with poor nutrient density and are associated with chronic conditions. Plant-based diets have gained popularity due to their ability to provide a nutritionally adequate healthy diet. This study aims to compare sociodemographic, socioeconomic, and health characteristics, and diet quality between Canadian adults following plant-based and omnivore diets as well as assess the extent to which key nutrient intakes are of public health concern among Canadians following plant-based diets. The study used nationally representative nutritional data from the 2015 Canadian Community Health Survey and descriptive statistics were computed. The analysis determined that Canadians following strict plant-based diets (1% of total population) were significantly more likely to be an immigrant to Canada, less likely to meet national physical activity guidelines, and less likely to be overweight, compared to Canadians following omnivore diets. Compared to omnivore diets, plant-based diets were nutritionally superior according to the Nutrient-Rich Food index. Continued knowledge translation on what comprises healthy plant-based diets, public guidance on the intersection between diet and health, and the completion of prospective cohort studies are needed. To conclude, the research suggests well-planned plant-based diets, in comparison to omnivore diets, offer a nutrient-dense diet.

The Experience of Phenylketonuria in Pregnancy and the Developing Maternal-Infant Relationship: A Qualitative Study.

Phenylketonuria (PKU) is a rare metabolic condition characterised by an inability to metabolise phenylalanine (Phe), found in many foods. When pregnant with PKU, women must adhere to a strict low-Phe diet. If they do not, foetal abnormalities or pregnancy loss can occur. Pregnancies are therefore closely clinically monitored and dominated by dietary management, leaving little "space" for women's emotional experience. This article explores the emotional impact of PKU during pregnancy and how this effects pre-natal bonding. Based on interviews with six women with PKU, conducted whilst they were pregnant, this article explores their unusual and previously undocumented experience. Image-making during interviews allowed women to uncover aspects of their experience that might otherwise have remained hidden. Interpretative phenomenological analysis of the transcripts and images generated five themes summarising the women's experiences. Some themes reiterated findings from previous studies, for example, the huge cognitive burden associated with PKU pregnancies and the importance of both expert and informal support to successful pregnancy management. However, new understanding also emerged, including rich description of the emotional load of these pregnancies and strategies that women use to manage this. Anxiety about baby safety was central to their experiences, and the effect of this on pre-natal bonding was explored. This article calls for increased formal and informal support for women with the emotional aspects of their PKU pregnancies, for example, the creation of "attachment-aware" services that support women with their anxiety, promoting strong pre-natal attachment and subsequently protecting maternal and infant mental health throughout pregnancy and beyond.

The Psychosocial Aspects of Vegetarian Diets: A Cross-Sectional Study of the Motivations, Risks, and Limitations in Daily Life.

The popularity of vegetarian and vegan diets is linked to various motivations, such as health, ethics, ecology, and social and religious influence. India has the highest proportion of vegetarians and vegans. The practise of these diets is linked to moral and health reasons and environmental concerns. Vegetarianism may also be associated with eating disorders such as orthorexia (ON). The main aim of this study was to determine the psychosocial aspects of vegetarian diets. Understanding these aspects is crucial for identifying potential risks and developing effective interventions. This study investigated the reasons for following vegetarian diets, the duration of dietary adherence, the occurrence of feelings of restriction in selected situations, and the risk of orthorexia and other eating disorders. A questionnaire survey was conducted among 186 individuals (82 vegetarians and 104 traditional dieters) between October 2023 and April 2024. The survey was administered via a Computer-Assisted Web Interview (CAWI) using Google Forms, distributed through social media, forums, and private messages. The inclusion criteria for the study group included consent, an age over 18, and a vegetarian diet, excluding those with eating disorders or diseases requiring strict diet therapy. The control group criteria were similar, excluding vegetarians and those requiring special diets. Four unreliable questionnaires were excluded from the analysis. The survey consisted of four sections: metric data, the ORTO-15 questionnaire, the EAT-26 questionnaire, and the TFEQ-13 questionnaire. The main motivations for following vegetarian diets were ethical and environmental (86.9%) and health (32.1%) reasons. Over half of the vegetarians had been following a plant-based diet for over five years. Vegetarians were more likely to feel restricted in restaurants and when grocery shopping. The ORTO-15 results indicate a higher risk of orthorexia among vegetarians (48.8% vs. 29.4% in the control group; p = 0.00673). The EAT-26 questionnaire showed a higher, but not statistically significant, risk of eating disorders among vegetarians (23.8% vs. 14.7%; p = 0.11391). The TFEQ-13 showed no significant differences between groups (Subscale 1: food restriction, p = 0.77279; Subscale 2: lack of control in overeating, p = 0.91935; Subscale 3: eating under the influence of emotions, p = 0.16612). This study concluded that ethical and environmental considerations and a belief in health benefits mainly drive vegetarians. An analysis of BMI revealed no significant differences between groups. The ORTO-15 results suggest a higher risk of orthorexia among vegetarians. The EAT-26 indicated a higher, but not statistically significant, risk of eating disorders among vegetarians and vegans. The TFEQ-13 showed no significant differences in restrictive eating, lack of control in overeating, and emotional eating. Vegetarians were likelier to encounter dietary difficulties in restaurants and shopping but less likely to feel socially excluded.

HUBUNGAN STATUS GIZI DAN STATUS MENSTRUASI DENGAN KEJADIAN ANEMIA PADA REMAJA PUTRI USIA 16-17 TAHUN DI PONDOK PESANTREN MAHFILUD DUROR II KABUPATEN JEMBER

Anemia can be caused by several factors, including nutritional status and the length of the menstrual cycle. Adolescent nutritional status is influenced by body image. so go on a strict diet. Blood loss every month (menstruation) too. impact on anemia. The aim of this study was to determine the relationship between nutritional status and menstrual status with the incidence of anemia in young women in. Mahfilud Islamic Boarding School. Duror II, Suger Kidul Village, Jelbuk District, Jember Regency, This research design uses a correlation method with a cross sectional approach. The population in this study were 104 young women at the Mahfilud Duror II Islamic Boarding School. The sample for this research was 82 young women. The sampling technique used was nonprobability sampling using purposive sampling. The instruments in this study were body scales, height measuring instruments, questionnaires, and easy touch GCHB. From the research it was found that nutritional status was normal (64.6%), normal menstrual status (53.7%), anemia status, no anemia (51.2%). The results of the Spearman's Rho statistical test with (a = 0.05) resulted in a p value of 0.139 so that H1 was rejected so H0 was accepted, which means there is no relationship between nutritional status and the incidence of anemia. The results of the second Spearman's Rho statistical test with (a = 0.05) resulted in a p value &lt;0.001 so that H2 was accepted, which means there is a relationship between menstrual status and the incidence of anemia at the Mahfilud Duror II Islamic Boarding School, Suger Kidul Village, Jelbuk District, Jember Regency with the strength of the relationship strong (r = 0.610). The coefficient number above is positive, so the better the menstrual status, the lower the anemia.

THE RELATIONSHIP BETWEEN OXYGEN SATURATION WITH LEVELS ANOREXIA IN DIABETES MELLITUS PATIENTS IN JEMBER

Background: Diabetes mellitus is widely known as a disease that is closely related to food intake, such as carbohydrates / sugar, protein, fat, and excessive energy can be an early risk factor for DM. Common problems in DM patients will experience a strict diet, and are at risk of eating disorders or can be called anorexia. Objective: determine the relationship between oxygen saturation and anorexia levels in DM patients in the jasmine inpatient room of RSD Balung. Research method: the research design used is correlational research with a cross sectional approach. The population of this study is patients suffering from diabetes mellitus in the jasmine inpatient room of RSUD Balung. The research sample of 50 people was taken using non-probability sampling techniques with the Quota sampling method. Datacollection used pulse oximetry analyzers to measure oxygen saturation and SNAQ questionnaires to measure anorexia levels. Uji statistics using the Chi-square test. Results of the analysis: the results of the study of the relationship of oxygen saturation with anorexia levels in DM patients obtained p-values (0.028 α (0.05) with contingency coefficient tests (0.354). Conclusion: there is a low relationship between oxygen saturation and anorexia levels in DM patients in the jasmine inpatient room of RSD Balung. Lack of nutrients will result in the breakdown of oxygen in the blood into fatty acids resulting in diabetic ketoacidosis. Lack of oxygen can also lead to weight loss. The body will be difficult to concentrate because the metabolic process is disrupted due to lack of oxygen supply in the blood that will circulate food throughout the body.

Predictive Modelling for Diabetes and Insulin Dosage Using Machine Learning

Now a days diabetes has become a chronic disease and managing this requires strict regular diet and workout to avoid various health issues and high blood glucose levels. To keep blood glucose at normal level in human body, diabetic patients have to be suggested with proper insulin dosage. It becomes difficult to predict the right amount of insulin to diabetes patients. To do this, Machine Learning(ML) method is used for identifying weather a person is suffering from diabetic and if he/she is suffering, right amount of insulin should be suggested to that patient. k-nearest neighbors(KNN) technique is employed to predict weather a patient is diabetic or not and Random Forest Regression technique is utilized for suggesting appropriate quantity of insulin dosage for the diabetic patient. Results are generated using the above-mentioned techniques.