In recent years, there has been a dramatic proliferation of research concerned with electronic products because of more various functions are integrate into the device and product's size has become smaller. As a result of these functional requirements, through silicon via (TSV) was investigated, this are getting considerable attentions not only from reducing the packaging size but also from shortening the interconnection's distance that can achieve the effect of enhancing signal transmission. TSVs are the vertical hole through the stacked IC, and they are also responsible for transferring signals between the ICs. Thus, they can improve the time delay of the signal transduction and allow better electrical performance than stacked ICs with wire bonding technology. However, a review of the literature indicates that electronic components will be affected easily by environmental factors such as humidity, pressure, and temperature. In general, the stacked ICs with TSV structure is easily affected by temperature changes than others factors since each material have different deformation. In very recently, the stacked IC packaging has been primarily concerned with thermo-mechanical loadings than traditional single IC packaging, which leads some problems such as via cracking, die cracking and interfacial delamination and so on. The above problems not only affect the performance of the device but also lead the device fail. Hence, most of the studies [1–9] are focus on discussing thermal mechanical loading with simulation method. Some of them discuss the relationship between the TSV shape and the stresses [4, 5]. In addition, most of people just build local TSV structure to do their research [4–9]. Although it can save more time but it also increase the error percentage with real situation. And this paper build the three dimensional four layers stacked IC packaging model from Hsieh [1]'s paper which can more close to real situation. And setting the structure to be simulated from the temperature 150°C to −50°C which is as retreat temperature. This paper use ANSYS software which is based on finite element theory in order to reduce time used and save money, as finite element simulation can provide results more quickly and cheaply than experiments. Moreover, the research mainly analyzes the average value of maximum von Mises stress in TSVs and chips. Besides, this paper will sort out geometries and material properties which will serious affect von Mises stress value by design of experiments (DoE) analysis. Through the DoE analysis, the critical factors are selected as main design factors to reduce the von Mises stresses. This study can provide the significant information to effectively design the products and increase the reliability. This information can also eliminate the testing time.
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