BackgroundMany vocational schools adopt the mode of integrating production and education and take the middle school and factory as the teaching background. The purpose of this study is to explore the influence of this educational strategy on students’ psychological stress.Subjects and MethodsThis study selected 200 students from a vocational college as the research object and randomly divided them into a control group and a study group. The control group adopted the traditional teaching mode. The research group adopted the teaching mode of integration production and education, and integration of school and enterprise. Hamilton Rating Scale for Anxiety (HAM-A) was used as a control for analysis, and statistical software SPSS 22.0 was used for data analysis.ResultsAfter six months of experimental research, the anxiety scale scores of students in the control group dropped from 22 to 18 points, and those in the study group dropped from 23 to 11 points. The psychological stress of the students in the study group was significantly different before and after the experiment (P<0.05). The experimental results show that the teaching mode combined with production and education can alleviate the psychological pressure of vocational college students.Conclusions In this study, the new teaching method combined with middle-class teaching can obviously relieve students’ psychological pressure. At the same time, it can also provide a reference for the administrators of other vocational colleges to promote the healthy development of education and the prosperity of the local economy.AcknowledgementGuangdong Province Education Science planning project (No. 2021GXJK658).