The Street Museum is the first nationwide initiative in Wuhan to apply new museology to the protection planning of historical streets. The Lihuangpi Road Street Museum is the first street museum in Wuhan. It has played an active role in protecting historical relics, showing the unique architectural style and spatial texture of Lihuangpi Road, reflecting urban diversity, improving the living environment, and promoting the development of cultural and leisure industries effect. However, problems such as irrationality in planning and design, low follow-up investment, lack of management and supervision, and inactive participation of community residents have affected its effectiveness. Through in-depth investigations and interviews, this article summarizes the practical results and problems of the Lihuangpi Road Street Museum since its establishment, and proposes targeted opinions, with a view to providing further reference for the protection and planning of historical blocks in other cities.